Mapping of single-stranded regions in duplex DNA at the sequence level: single-strand-specific cytosine methylation in RNA polymerase-promoter complexes.

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

A new method for sequencing DNA.

1977 • 7,941 citations

REGULATORY SEQUENCES INVOLVED IN THE PROMOTION AND TERMINATION OF RNA TRANSCRIPTION

1979 • 2,730 citations

DNAase footprinting a simple method for the detection of protein-DNA binding specificity

1978 • 2,092 citations

The use of thin acrylamide gels for DNA sequencing

1978 • 1,449 citations

The tac promoter: a functional hybrid derived from the trp and lac promoters.

1983 • 1,001 citations

Direct chemical method for sequencing RNA.

1979 • 940 citations

E. coli RNA polymerase interacts homologously with two different promoters

1980 • 911 citations

Chemical probes for higher-order structure in RNA.

1980 • 415 citations

Effects of Some Chemical Mutagens and Carcinogens on Nucleic Acids

1966 • 370 citations

Purification and properties of the .sigma. subunit of Escherichia coli DNA-dependent RNA polymerase

1979 • 319 citations

RNA polymerase unwinds an 11-base pair segment of a phage T7 promoter

1979 • 181 citations

Mapping the topography of DNA wrapped around gyrase by nucleolytic and chemical probing of complexes of unique DNA sequences

1981 • 171 citations

Spacer mutations in the lac ps promoter.

1982 • 156 citations

Contacts between Escherichia coli RNA polymerase and a lac operon promoter.

1978 • 148 citations

Promoter-specific inhibition of transcription by antibiotics which act on DNA gyrase

1978 • 130 citations

Differential sensitivity of gene expression in vitro to inhibitors of DNA gyrase.

1979 • 114 citations

Is DNA really a double helix?

1979 • 87 citations

Chemical probing of the tRNA--ribosome complex.

1981 • 66 citations

Nucleotide sequence of the promoter-operator region of the tryptophan operon of Escherichia coli

1978 • 64 citations

A Study of Unwinding of DNA and Shielding of the DNA Grooves by RNA Polymerase by Using Methylation with Dimethylsulphate

1978 • 57 citations

Escherichia coli RNA polymerase and trp repressor interaction with the promoter-operator region of the tryptophan operon of Salmonella typhimurium

1980 • 54 citations

Promoter melting by T7 ribonucleic acid polymerase as detected by single-stranded endonuclease digestion

1980 • 43 citations

Functional analysis of wild-type and altered tryptophan operon promoters of Salmonella typhimurium in Escherichia coli

1980 • 22 citations