Differential sensitivity of gene expression in vitro to inhibitors of DNA gyrase.

Analysis of bacteriophage T7 early RNAs and proteins on slab gels

1973 • 2,246 citations

SUPERCOILED CIRCULAR DNA-PROTEIN COMPLEX IN Escherichia coli : PURIFICATION AND INDUCED CONVERSION TO AN OPEN CIRCULAR DNA FORM

1969 • 1,847 citations

DNA gyrase: an enzyme that introduces superhelical turns into DNA.

1976 • 1,175 citations

Nalidixic acid resistance: A second genetic character involved in DNA gyrase activity

1977 • 828 citations

Mechanism of action of nalidixic acid: Purification of Escherichia coli nalA gene product and its relationship to DNA gyrase and a novel nicking-closing enzyme

1977 • 777 citations

Novobiocin and coumermycin inhibit DNA supercoiling catalyzed by DNA gyrase.

1976 • 719 citations

IN VITRO SYNTHESIS OF PROTEIN IN MICROBIAL SYSTEMS

1973 • 675 citations

Plasmid ColE1 as a Molecular Vehicle for Cloning and Amplification of DNA

1974 • 541 citations

Formation, induction, and curing of bacteriophage P1 lysogens

1972 • 435 citations

Proteins that Affect DNA Conformation

1978 • 215 citations

Purification and Characterization of Colicin E2 and Colicin E3

1967 • 197 citations

Plasmid Detection and Sizing in Single Colony Lysates

1977 • 190 citations

Isolation of a Specialized Lambda Transducing Bacteriophage Carrying the Beta Subunit Gene for Escherichia coli Ribonucleic Acid Polymerase

1973 • 168 citations

Interaction of RNA Polymerase with Promoters from Bacteriophage fd

1977 • 156 citations

Contacts between Escherichia coli RNA polymerase and a lac operon promoter.

1978 • 148 citations

Angular Alteration of the DNA Helix by E. coli RNA Polymerase

1972 • 145 citations

Promoter-specific inhibition of transcription by antibiotics which act on DNA gyrase

1978 • 130 citations

An electron microscopic comparison of transcription on linear and superhelical DNA

1976 • 127 citations

Detection and Isolation of the Repressor Protein for the Tryptophan Operon of Escherichia coli

1972 • 122 citations

Template activities of the Φη-174 replicative allomorphic deoxyribonucleic acids

1971 • 100 citations

Mode of Action of Novobiocin in Escherichia coli

1967 • 99 citations

Mapping of a cluster of genes for components of the transcriptional and translational machineries of Escherichia coli

1977 • 97 citations

Synthesis of an R plasmid protein associated with tetracycline resistance is negatively regulated.

1976 • 90 citations

Initiation of transcription by Escherichia coli RNA polymerase from supercoiled and non-supercoiled bacteriophage PM2 DNA

1975 • 87 citations

Replication of Escherichia coli DNA in vitro: Inhibition by Oxolinic Acid

1976 • 63 citations

Involvement of DNA gyrase in bacteriophage T7 DNA replication

1977 • 56 citations

Mechanism of transcription of bacteriophage S13

1973 • 49 citations

The effect of nalidixic acid on the expression of some genes in Escherichia coli K-12

1975 • 42 citations

A possible termination factor for transcription in Escherichia coli

1974 • 18 citations