Mapping the topography of DNA wrapped around gyrase by nucleolytic and chemical probing of complexes of unique DNA sequences

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

DNAase footprinting a simple method for the detection of protein-DNA binding specificity

1978 • 2,092 citations

Complete Nucleotide Sequence of the Escherichia coli Plasmid pBR322

1979 • 1,807 citations

Analysis of restriction fragments of T7 DNA and determination of molecular weights by electrophoresis in neutral and alkaline gels

1977 • 1,607 citations

DNA gyrase: an enzyme that introduces superhelical turns into DNA.

1976 • 1,175 citations

Chain length determination of small double- and single-stranded DNA molecules by polyacrylamide gel electrophoresis

1975 • 1,135 citations

Nalidixic acid resistance: A second genetic character involved in DNA gyrase activity

1977 • 828 citations

Mechanism of action of nalidixic acid: Purification of Escherichia coli nalA gene product and its relationship to DNA gyrase and a novel nicking-closing enzyme

1977 • 777 citations

DNA Gyrase and the Supercoiling of DNA

1980 • 713 citations

Type II DNA topoisomerases: Enzymes that can unknot a topologically knotted DNA molecule via a reversible double-strand break

1980 • 547 citations

Internal structure of the chromatin subunit

1974 • 423 citations

Energy coupling in DNA gyrase and the mechanism of action of novobiocin

1978 • 403 citations

Decomposition of the linking number of a closed ribbon: A problem from molecular biology

1978 • 353 citations

A Sign Inversion Mechanism for Enzymatic Supercoiling of DNA

1979 • 325 citations

Covalent bonds between protein and DNA. Formation of phosphotyrosine linkage between certain DNA topoisomerases and DNA.

1980 • 314 citations

ATP-dependent DNA topoisomerase from D. melanogaster reversibly catenates duplex DNA rings

1980 • 292 citations

DNA gyrase action involves the introduction of transient double-strand breaks into DNA.

1980 • 237 citations

Formation and resolution of DNA catenanes by DNA gyrase

1980 • 226 citations

Precise location of DNase I cutting sites in the nucleosome core determined by high resolution gel electrophoresis

1979 • 213 citations

Micrococcus luteus DNA gyrase: active components and a model for its supercoiling of DNA.

1978 • 206 citations

Site-specific cleavage of DNA by E. coli DNA gyrase

1979 • 205 citations

DNA-DNA gyrase complex: the wrapping of the DNA duplex outside the enzyme

1978 • 195 citations

Periodicity of Deoxyribonuclease I Digestion of Chromatin

1979 • 160 citations

In vitro catenation and decatenation of DNA and a novel eucaryotic ATP-dependent topoisomerase

1980 • 134 citations

Deoxyribonucleic acidgyrase-deoxyribonucleic acid complex containing 140 base pairs of deoxyribonucleic acid and an .alpha.2.beta.2 protein core

1980 • 131 citations

Reaction of nucleosome DNA with dimethyl sulfate.

1979 • 103 citations

DNAase I, DNAase II and staphylococcal nuclease cut at different, yet symmetrically located, sites in the nucleosome core

1978 • 102 citations

Interaction between DNA gyrase and its cleavage site on DNA.

1980 • 96 citations

A restriction enzyme Tha I from the thermophilic mycoplasma Thermoplasma acidophilum

1978 • 92 citations

Pancreatic DNAase cleavage sites in nuclei

1977 • 86 citations

DNA gyrase subunit stoichiometry and the covalent attachment of subunit A to DNA during DNA cleavage

1980 • 85 citations

The separation of DNA segments attached to proteins

1979 • 64 citations

Filter-binding assay for covalent DNA-protein complexes: adenovirus DNA-terminal protein complex.

1978 • 57 citations

Deoxyribonuclease I produces staggered cuts in the DNA of chromatin

1977 • 46 citations