Restoration of inactivation and block of open sodium channels by an inactivation gate peptide

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Ionic channels of excitable membranes

1985 • 7,199 citations

Ionic Channels of Excitable Membranes

1985 • 3,014 citations

Biophysical and Molecular Mechanisms of Shaker Potassium Channel Inactivation

1990 • 1,528 citations

Inactivation of the sodium channel. I. Sodium current experiments.

1977 • 1,509 citations

Neurotoxins that Act on Voltage-Sensitive Sodium Channels in Excitable Membranes

1980 • 1,236 citations

Structural parts involved in activation and inactivation of the sodium channel

1989 • 1,189 citations

Inactivation of the sodium channel. II. Gating current experiments.

1977 • 943 citations

A cluster of hydrophobic amino acid residues required for fast Na(+)-channel inactivation.

1992 • 810 citations

Restoration of Inactivation in Mutants of Shaker Potassium Channels by a Peptide Derived from ShB

1990 • 752 citations

An LFA-3 cDNA encodes a phospholipid-linked membrane protein homologous to its receptor CD2

1987 • 699 citations

A reinterpretation of mammalian sodium channel gating based on single channel recording

1983 • 675 citations

Destruction of Sodium Conductance Inactivation in Squid Axons Perfused with Pronase

1973 • 540 citations

Identification of an Intracellular Peptide Segment Involved in Sodium Channel Inactivation

1988 • 382 citations

Anatomy of a Conformational Change: Hinged "Lid" Motion of the Triosephosphate Isomerase Loop

1990 • 282 citations

Histochemical staining of clonal mammalian cell lines expressingE. coli ? galactosidase indicates heterogeneous expression of the bacterial gene

1987 • 232 citations

An Integrated view of the Molecular Toxinology of Sodium Channel Gating in Excitable Cells

1987 • 221 citations

Inhibition of inactivation of single sodium channels by a site-directed antibody.

1989 • 218 citations

Local anesthetic block of sodium channels in normal and pronase-treated squid giant axons

1978 • 204 citations

Panning transfected cells for electrophysiological studies.

1993 • 189 citations

Interactions of amino terminal domains of Shaker K channels with a pore blocking site studied with synthetic peptides.

1993 • 148 citations

μl Na+ channels expressed transiently in human embryonic kidney cells: Biochemical and biophysical properties

1992 • 137 citations

Efficient expression of rat brain type IIA Na+ channel α subunits in a somatic cell line

1992 • 119 citations

Changes in Sodium Channel Gating Produced by Point Mutations in a Cytoplasmic Linker

1990 • 93 citations

Voltage-dependent ion channels and their gating

1992 • 90 citations

Simulation of Na channel inactivation by thiazine dyes.

1982 • 60 citations

A peptide segment critical for sodium channel inactivation functions as an inactivation gate in a potassium channel

1993 • 52 citations