A New Trigger for T Cells

Fundamental Immunology

1999 • 1,011 citations

LIGAND RECOGNITION BY αβ T CELL RECEPTORS

1998 • 904 citations

Recruitment of Nck by CD3ϵ Reveals a Ligand-Induced Conformational Change Essential for T Cell Receptor Signaling and Synapse Formation

2002 • 442 citations

Initiation of Signal Transduction through the T Cell Receptor Requires the Multivalent Engagement of Peptide/MHC Ligands

1998 • 379 citations

The specificity of TCR/pMHC interaction

2002 • 295 citations

Two-step binding mechanism for T-cell receptor recognition of peptide–MHC

2002 • 279 citations

A Piston Model for Transmembrane Signaling of the Aspartate Receptor

1999 • 265 citations

The Relationship of MHC-Peptide Binding and T Cell Activation Probed Using Chemically Defined MHC Class II Oligomers

2000 • 254 citations

Phosphorylation of T cell receptor zeta is regulated by a lipid dependent folding transition.

2000 • 249 citations

A T Cell Receptor CDR3β Loop Undergoes Conformational Changes of Unprecedented Magnitude Upon Binding to a Peptide/MHC Class I Complex

2002 • 206 citations

T cell receptor signalling

2001 • 188 citations

Mechanisms Contributing to T Cell Receptor Signaling and Assembly Revealed by the Solution Structure of an Ectodomain Fragment of the CD3ϵγ Heterodimer

2001 • 171 citations

Allosteric Activation of a Spring-Loaded Natriuretic Peptide Receptor Dimer by Hormone

2001 • 164 citations

Multivalent structure of an αβT cell receptor

1999 • 140 citations

The TCR Triggering Puzzle

2001 • 96 citations

Conformational changes of ribose-binding protein and two related repressors are tailored to fit the functional need

1999 • 29 citations