Correlation of VEGF and Angiopoietin Expression with Disruption of Blood–Brain Barrier and Angiogenesis after Focal Cerebral Ischemia

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

Vascular-specific growth factors and blood vessel formation

2000 • 3,667 citations

Angiopoietin-2, a Natural Antagonist for Tie2 That Disrupts in vivo Angiogenesis

1997 • 3,470 citations

Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis.

1995 • 3,139 citations

Isolation of Angiopoietin-1, a Ligand for the TIE2 Receptor, by Secretion-Trap Expression Cloning

1996 • 1,969 citations

Vascular niche for adult hippocampal neurogenesis

2000 • 1,805 citations

Leakage-Resistant Blood Vessels in Mice Transgenically Overexpressing Angiopoietin-1

1999 • 1,372 citations

Angiopoietin-1 protects the adult vasculature against plasma leakage

2000 • 1,271 citations

VEGF enhances angiogenesis and promotes blood-brain barrier leakage in the ischemic brain

2000 • 1,218 citations

Transcriptional Regulation of the Rat Vascular Endothelial Growth Factor Gene by Hypoxia

1995 • 1,087 citations

A Functional MRI Study of Subjects Recovered From Hemiparetic Stroke

1997 • 998 citations

Role of angiogenesis in patients with cerebral ischemic stroke.

1994 • 820 citations

Increased Vascularization in Mice Overexpressing Angiopoietin-1

1998 • 818 citations

VEGF Gene Delivery to Myocardium

2000 • 692 citations

Hypoxia-Induced Vascular Endothelial Growth Factor Expression Precedes Neovascularization after Cerebral Ischemia

2000 • 641 citations

Vascular endothelial growth factor (VEGF) induces plasminogen activators and plasminogen activator inhibitor-1 in microvascular endothelial cells

1991 • 626 citations

Angiopoietin-1 induces sprouting angiogenesis in vitro

1998 • 467 citations

Comparison of VEGF, VEGF-B, VEGF-C and Ang-1 mRNA regulation by serum, growth factors, oncoproteins and hypoxia

1997 • 459 citations

VEGF antagonism reduces edema formation and tissue damage after ischemia/reperfusion injury in the mouse brain

1999 • 457 citations

Heterogeneity of the Angiogenic Response Induced in Different Normal Adult Tissues by Vascular Permeability Factor/Vascular Endothelial Growth Factor

2000 • 421 citations

The role of vascular endothelial growth factor in pathological angiogenesis

1995 • 419 citations

Endothelial Trophic Support of Neuronal Production and Recruitment from the Adult Mammalian Subependyma

1999 • 384 citations

Regulation of Angiopoietin-2 mRNA Levels in Bovine Microvascular Endothelial Cells by Cytokines and Hypoxia

1998 • 379 citations

Oxygen Sensing, Hypoxia-Inducible Factor-1 and the Regulation of Mammalian Gene Expression

1998 • 362 citations

Exogenous vascular endothelial growth factor induces malformed and hyperfused vessels during embryonic neovascularization.

1995 • 338 citations

A rat model of focal embolic cerebral ischemia

1997 • 324 citations

Recovery recapitulates ontogeny

2000 • 318 citations

Rapid Induction of Vascular Endothelial Growth Factor Gene Expression After Transient Middle Cerebral Artery Occlusion in Rats

1997 • 311 citations

Angiopoietin-2 at high concentration can enhance endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway

2000 • 299 citations

Cell turnover of capillaries.

1967 • 294 citations

Vascular Bed–specific Expression of an Endothelial Cell Gene Is Programmed by the Tissue Microenvironment

1997 • 269 citations

A new communication system between hepatocytes and sinusoidal endothelial cells in liver through vascular endothelial growth factor and Flt tyrosine kinase receptor family (Flt-1 and KDR/Flk-1).

1994 • 258 citations

Cell Type Specific Upregulation of Vascular Endothelial Growth Factor in an MCA-occlusion Model of Cerebral Infarct

1999 • 240 citations

Expression of Vascular Endothelial Growth Factor (VEGF) and its Receptors (Flt-1 and Flk-1) following Permanent and Transient Occlusion of the Middle Cerebral Artery in the Rat

1998 • 236 citations

Serial Measurement of Vascular Endothelial Growth Factor and Transforming Growth Factor-β1 in Serum of Patients With Acute Ischemic Stroke

2000 • 231 citations

Glomeruloid Microvascular Proliferation Follows Adenoviral Vascular Permeability Factor/Vascular Endothelial Growth Factor-164 Gene Delivery

2001 • 216 citations

Expression of Angiopoietin-1, Angiopoietin-2, and Tie Receptors after Middle Cerebral Artery Occlusion in the Rat

2000 • 194 citations

Evolving stroke and the ischemic penumbra

1996 • 191 citations

Angiogenesis in developing rat brain: An in vivo and in vitro study

1985 • 184 citations

Brain microvessels: factors altering their patency after the occlusion of a middle cerebral artery (Wistar rat).

1994 • 166 citations

Molecular analysis of blood vessel formation and disease

1997 • 163 citations

Angiopoietin-1 reduces cerebral blood vessel leakage and ischemic lesion volume after focal cerebral embolic ischemia in mice

2002 • 162 citations

Development and differentiation of endothelium

1998 • 156 citations

Angiogenesis in Embryos and Ischemic Diseases

1997 • 139 citations

Induction of Angiopoietin and Tie Receptor mRNA Expression after Cerebral Ischemia–Reperfusion

2000 • 136 citations

Cerebral Microvascular Obstruction by Fibrin is Associated with Upregulation of PAI-1 Acutely after Onset of Focal Embolic Ischemia in Rats

1999 • 124 citations

Vascular endothelial growth factor expression in transient focal cerebral ischemia in the rat

1998 • 119 citations

Vascular Growth Factors in Cerebral Ischemia

2001 • 88 citations

Blood flow through cerebral collateral vessels one month after middle cerebral artery occlusion.

1987 • 86 citations

Ultrastructural changes in the capillary bed of the rat cerebral cortex in anoxic-ischemic brain lesions.

1964 • 85 citations

Up-Regulation of Neuropilin-1 in Neovasculature after Focal Cerebral Ischemia in the Adult Rat

2001 • 85 citations

Diameter and length changes in cerebral collaterals after middle cerebral artery occlusion in the young rat

1984 • 78 citations

Two Functional Forms of Vascular Endothelial Growth Factor Receptor-2/Flk-1 mRNA Are Expressed in Normal Rat Retina

1998 • 58 citations

Quantitation of Microvascular Plasma Perfusion and Neuronal Microtubule-Associated Protein in Ischemic Mouse Brain by Laser-Scanning Confocal Microscopy

1999 • 53 citations

Imaging System for Three-Dimensional Mapping of Cerebrocortical Capillary Networks in Vivo

1993 • 50 citations

Parenchymal microvascular systems and cerebral atrophy in spontaneously hypertensive rats

1993 • 48 citations

The microvascular system in ischemic cortical lesions

1996 • 39 citations

Three-dimensional morphological study of microvascular regeneration in cavity wall of the rat cerebral cortex using the scanning electron microscope: Implications for delayed neural grafting into brain cavities

1995 • 33 citations

<title>Fast skeletonization algorithm for 3D elongated objects</title>

2001 • 30 citations

<title>Voxel-coding method for quantification of vascular structure from 3D images</title>

2001 • 6 citations