Two novel σ receptor ligands, BD1047 and LR172, attenuate cocaine-induced toxicity and locomotor activity

Sigma receptors: biology and function.

1990 • 799 citations

Rat liver and kidney contain high densities of σ1 and σ2 receptors: characterization by ligand binding and photoaffinity labeling

1994 • 423 citations

Characterization of two novel σ receptor ligands: antidystonic effects in rats suggest σ receptor antagonism

1995 • 253 citations

Clinical Pharmacology and Toxicology of Cocaine

1993 • 215 citations

Cocaine binding at σ receptors

1988 • 208 citations

Brain Concentrations of Cocaine and Benzoylecgonine in Fatal Cases

1985 • 156 citations

Synthesis and evaluation of optically pure [³H]‐(+)‐pentazocine, a highly potent and selective radioligand for σ receptors

1989 • 141 citations

Endogenous ligands for sigma opioid receptors in the brain (“sigmaphin”): Evidence from binding assays

1986 • 117 citations

Cocaine-induced seizures and lethality appear to be associated with distinct central nervous system binding sites.

1993 • 93 citations

Novel σ receptor ligands attenuate the locomotor stimulatory effects of cocaine

1999 • 80 citations

Cocaine-induced convulsions: pharmacological antagonism at serotonergic, muscarinic and sigma receptors

1997 • 66 citations

Synthesis, characterization, and biological evaluation of a novel class of N-(arylethyl)-N-alkyl-2-(1-pyrrolidinyl)ethylamines: structural requirements and binding affinity at the .sigma. receptor

1992 • 64 citations

Cocaine Receptors on Dopamine Transporters Mediate Cocaine-Reinforced Behavior

1988 • 38 citations

Down-regulation of sigma receptors by chronic haloperidol.

1990 • 25 citations

Neuropharmacological profile of EMD 57445, a σ receptor ligand with potential antipsychotic activity

1996 • 25 citations

Novel NMDA/glycine site antagonists attenuate cocaine-induced behavioral toxicity

1997 • 23 citations

Focal stimulation of specific pathways in the rat hippocampus causes a reduction in radioligand binding to the haloperidol-sensitive sigma receptor

1991 • 18 citations

Microinjection of sigma ligands into cranial nerve nuclei produces vacuous chewing in rats

1998 • 15 citations