Novel σ receptor ligands attenuate the locomotor stimulatory effects of cocaine

Rat liver and kidney contain high densities of σ1 and σ2 receptors: characterization by ligand binding and photoaffinity labeling

1994 • 423 citations

Characterization of two novel σ receptor ligands: antidystonic effects in rats suggest σ receptor antagonism

1995 • 253 citations

Synthesis and evaluation of optically pure [³H]‐(+)‐pentazocine, a highly potent and selective radioligand for σ receptors

1989 • 141 citations

Selective σ ligands block stimulant effects of cocaine

1991 • 95 citations

Synthesis, characterization, and biological evaluation of a novel class of N-(arylethyl)-N-alkyl-2-(1-pyrrolidinyl)ethylamines: structural requirements and binding affinity at the .sigma. receptor

1992 • 64 citations

Effects of the selective sigma receptor ligand, 6-[6-(4-hydroxypiperidinyl)hexyloxy]-3-methylflavone (NPC 16377), on behavioral and toxic effects of cocaine.

1993 • 61 citations

Synthesis and evaluation of conformationally restricted N-[2-(3,4-dichlorophenyl)ethyl]-N-methyl-2-(1-pyrrolidinyl)ethylamines at .sigma. receptors. 2. Piperazines, bicyclic amines, bridged bicyclic amines, and miscellaneous compounds

1993 • 58 citations

β-Adrenergic Antagonism Alters the Behavioral and Neurochemical Responses to Cocaine

1996 • 55 citations

Cocaine Receptors on Dopamine Transporters Mediate Cocaine-Reinforced Behavior

1988 • 38 citations

Down-regulation of sigma receptors by chronic haloperidol.

1990 • 25 citations