Platelet-Endothelial Cell Interactions During Ischemia/Reperfusion: The Role of P-Selectin

A platelet alpha-granule membrane protein (GMP-140) is expressed on the plasma membrane after activation.

1985 • 886 citations

Leukocyte accumulation promoting fibrin deposition is mediated in vivo by P-selectin on adherent platelets

1992 • 800 citations

P-selectin glycoprotein ligand-1 mediates rolling of human neutrophils on P-selectin.

1995 • 712 citations

Stimulated secretion of endothelial von Willebrand factor is accompanied by rapid redistribution to the cell surface of the intracellular granule membrane protein GMP-140

1989 • 653 citations

Activated platelets signal chemokine synthesis by human monocytes.

1996 • 598 citations

Sequential contribution of L- and P-selectin to leukocyte rolling in vivo.

1995 • 597 citations

Transcellular activation of platelets and endothelial cells by bioactive lipids in platelet microparticles.

1997 • 486 citations

Neutrophil rolling, arrest, and transmigration across activated, surface-adherent platelets via sequential action of P-selectin and the beta 2-integrin CD11b/CD18

1996 • 484 citations

Platelets roll on stimulated endothelium in vivo: an interaction mediated by endothelial P-selectin.

1995 • 467 citations

Sticky sugars for selectins

1991 • 456 citations

Platelet factor 4 is chemotactic for neutrophils and monocytes.

1981 • 444 citations

Neutrophil rolling, arrest, and transmigration across activated, surface-adherent platelets via sequential action of P-selectin and the beta 2-integrin CD11b/CD18

1996 • 400 citations

Induction of Cytokine Expression in Leukocytes by Binding of Thrombin-Stimulated Platelets

1997 • 385 citations

Cloning of the mouse endothelial selectins. Expression of both E- and P-selectin is inducible by tumor necrosis factor alpha.

1992 • 383 citations

Molecular mechanisms of leukocyte recruitment in the inflammatory process

1996 • 354 citations

Inflammatory roles of P-selectin.

1993 • 336 citations

P-selectin/ICAM-1 double mutant mice: acute emigration of neutrophils into the peritoneum is completely absent but is normal into pulmonary alveoli.

1995 • 287 citations

P-Selectin Glycoprotein Ligand-1 (PSGL-1) on T Helper 1 but Not on T Helper 2 Cells Binds to P-Selectin and Supports Migration into Inflamed Skin

1997 • 278 citations

Hypoxia-induced exocytosis of endothelial cell Weibel-Palade bodies. A mechanism for rapid neutrophil recruitment after cardiac preservation.

1996 • 276 citations

Leukocyte rolling in vivo is mediated by P-selectin glycoprotein ligand- 1

1995 • 258 citations

P-selectin glycoprotein ligand-1 is broadly expressed in cells of myeloid, lymphoid, and dendritic lineage and in some nonhematopoietic cells

1996 • 254 citations

Cap Image - ein neuartiges computerunterstütztes Videobildanalysesystem für die dynamische Kapillarmikroskopie - Cap Image - A Newly-developed Computer-aided Videoframe Analysis System for Dynamic Capillaroscopy

1997 • 238 citations

Selectin-mediated rolling of neutrophils on immobilized platelets

1993 • 236 citations

Effect of Aspirin on Thrombin-Induced Adherence of Platelets to Cultured Cells from the Blood Vessel Wall

1978 • 184 citations

Role of P-selectin and leukocyte activation in polymorphonuclear cell adhesion to surface adherent activated platelets under physiologic shear conditions (an injury vessel wall model)

1994 • 178 citations

Wall shear rate in arterioles in vivo: least estimates from platelet velocity profiles

1988 • 155 citations

Platelet Activation by Superoxide Anion and Hydroxyl Radicals Intrinsically Generated by Platelets That Had Undergone Anoxia and Then Reoxygenated

1997 • 149 citations

The Molecular Basis of Platelet and Endothelial Cell Interaction with Neutrophils and Monocytes: Role of P-Selectin and the P-Selectin Ligand, PSGL-1

1995 • 139 citations

Alterations of Coagulation and Fibrinolytic and Kallikrein-Kinin Systems in the Acute and Postacute Phases in Patients With Unstable Angina Pectoris

1995 • 130 citations

ISCHEMIA/REPERFUSION-INDUCED LEUKOCYTE-ENDOTHELIAL INTERACTIONS IN POSTCAPILLARY VENULES

1997 • 125 citations

Chemokine and chemokine receptor mRNA expression in human platelets

1995 • 114 citations

Chemokines in stored platelet concentrates

1996 • 110 citations

Platelet—neutrophil interactions: Their significance

1992 • 107 citations

Neutrophil Depletion Suppresses 111In-Labeled Platelet Accumulation in Infarcted Myocardium

1985 • 95 citations

Role of Mac-1 and ICAM-1 in ischemia-reperfusion injury in a microcirculation model of BALB/C mice

1994 • 91 citations

Platelet‐induced neutrophil activation: platelet‐expressed fibrinogen induces the oxidative burst in neutrophils by an interaction with CD11C/CD18

1995 • 90 citations

Skeletal muscle microvascular and tissue injury after varying durations of ischemia

1996 • 85 citations

Concentration profile of blood platelets differs in arterioles and venules

1992 • 84 citations

Thrombin-activated Human Platelets Release two NAP-2 Variants that Stimulate Polymorphonuclear Leukocytes

1996 • 74 citations

Reactive Oxygen Species and Platelet Activation in Reperfusion Injury

1997 • 73 citations

Platelet Activation and Interactions with the Microvasculature

1996 • 69 citations

Adhesion of flowing leucocytes to immobilized platelets

1995 • 67 citations

Quantitative analysis of small intestinal microcirculation in the mouse

1998 • 65 citations

Effects of leukocyte and platelet depletion on ischemia-reperfusion injury to dog pancreas

1994 • 62 citations

Cyclic GMP but not cyclic AMP prevents renal platelet accumulation after ischemia-reperfusion in anesthetized rats.

1994 • 53 citations

Platelet adhesion receptors

1995 • 45 citations

Pathways of oxygen utilization by stimulated platelets and leukocytes.

1979 • 43 citations

Impact of leukocyte adhesion on myocardial ischemia/reperfusion injury: conceivable mechanisms and proven facts.

1993 • 33 citations

Leukocyte and Platelet Depletion Protects the Liver from Damage Induced by Cholestasis and Ischemia–Reperfusion in the Dog

1996 • 20 citations

Carolina rinse attenuates postischemic microvascular injury in rat small bowel isografts

1998 • 17 citations

Human blood platelet serotonin studiedin vitro: endogenous serotonin may stimulate thrombin-induced serotonin release in stored platelets

1996 • 16 citations

Carolina rinse attenuates postischemic microvascular injury in rat small bowel isografts.

1998 • 16 citations

Rat Platelets Adhere to Human Thrombin-Treated Rat Lungs under Flow Conditions

1989 • 9 citations