Microcirculatory derangements in acute pancreatitis

Inflammatory mediators in acute pancreatitis

2000 • 507 citations

Hepatic microcirculatory perfusion failure is a determinant of liver dysfunction in warm ischemia-reperfusion.

1994 • 374 citations

Susceptibility of the Pancreas to Ischemic Injury in Shock

1978 • 308 citations

Pancreatic ischaemia in experimental acute pancreatitis: Mechanism, significance and therapy

1990 • 276 citations

Microvascular ischemia-reperfusion injury in striated muscle: significance of "reflow paradox"

1992 • 270 citations

The role of intercellular adhesion molecule 1 and neutrophils in acute pancreatitis and pancreatitis-associated lung injury

1999 • 263 citations

Fatal pancreatitis, a consequence of excessive leukocyte stimulation?

1988 • 212 citations

PMN-Elastase in Comparison with CRP, Antiproteases, and LDH as Indicators of Necrosis in Human Acute Pancreatitis

1991 • 201 citations

Risk Factors for Pancreatic Cellular Injury After Cardiopulmonary Bypass

1992 • 201 citations

CT diagnosis and staging of acute pancreatitis.

1989 • 192 citations

Microvascular ischemia-reperfusion injury in striated muscle: significance of "no reflow"

1992 • 175 citations

Inflammatory mediators in acute pancreatitis

1995 • 169 citations

Ethanol and the pancreas

1990 • 158 citations

Granulocyte elastase in assessment of severity of acute pancreatitis

1990 • 156 citations

Transition of pancreatic edema into pancreatic necrosis.

1948 • 145 citations

Impact of leukocyte-endothelial cell interaction in hepatic ischemia-reperfusion injury

1994 • 142 citations

Effect of temporary ischemia upon development and histological patterns of acute pancreatitis in the rat

1989 • 132 citations

Specific Therapy for Local and Systemic Complications of Acute Pancreatitis With Monoclonal Antibodies Against ICAM-1

1999 • 129 citations

Pancreatic microcirculatory changes in experimental pancreatitis of graded severity in the rat.

1994 • 128 citations

Clinical usefulness of polymorphonuclear elastase in predicting the severity of acute pancreatitis: Results of a multicentre study

1991 • 125 citations

A monoclonal anti-interleukin 8 antibody (WS-4) inhibits cytokine response and acute lung injury in experimental severe acute necrotising pancreatitis in rabbits

1998 • 119 citations

Impairment of pancreatic microcirculation correlates with the severity of acute experimental pancreatitis.

1994 • 116 citations

Arterial constriction, ischemia-reperfusion, and leukocyte adherence in acute pancreatitis

1993 • 111 citations

Acute pancreatitis after cardiopulmonary bypass

1985 • 107 citations

Dynamic contrast enhanced computed tomography: a precise technique for identifying and localising pancreatic necrosis.

1990 • 107 citations

Ischemia/Reperfusion-Induced Pancreatitis

2000 • 105 citations

Gradations of pancreatitis, edematous, through hemorrhagic, experimentally produced by controlled injection of microspheres into blood vessels in dogs.

1962 • 104 citations

Hyperamylasemia After Cardiac Surgery

1989 • 103 citations

RISK FACTORS FOR POSTIMPLANTATION PANCREATITIS AND PANCREATIC THROMBOSIS IN PANCREAS TRANSPLANT RECIPIENTS

1993 • 102 citations

Intravenous Contrast Medium Aggravates the Impairment of Pancreatic Microcirculation in Necrotizing Pancreatitis in the Rat

1995 • 99 citations

The role of ischemia in acute pancreatitis: studies with an isolated perfused canine pancreas.

1982 • 96 citations

Ischemia reperfusion of the pancreas: A new in vivo model for acute pancreatitis in rats

1995 • 95 citations

Microcirculation of the pancreas. A quantitative study of physiology and changes in pancreatitis.

1990 • 91 citations

Ischemia-reperfusion-induced pancreatic microvascular injury

1996 • 88 citations

Therapeutic Effect of Isovolemic Hemodilution with Dextran 60 on the Impairment of Pancreatic Microcirculation in Acute Biliary Pancreatitis

1990 • 84 citations

Circulatory Changes in Acute Pancreatitis

1967 • 83 citations

Amelioration of experimental acute pancreatitis with a potent platelet-activating factor antagonist

1994 • 82 citations

Morphological studies of graft pancreatitis following pancreas transplantation

1993 • 81 citations

Microcirculatory changes in sodium taurocholate-induced pancreatitis in rats

1991 • 79 citations

Native and graft pancreatitis following combined pancreas—renal transplantation

1993 • 77 citations

Incidence, management and significance of surgical complications after pancreatic transplantation.

1993 • 76 citations

Interleukins in Acute Pancreatitis

1996 • 75 citations

Effect of endothelin and endothelin receptor blockade on capillary permeability in experimental pancreatitis

2000 • 75 citations

Microcirculatory dynamics in the normal and inflamed pancreas

1968 • 71 citations

Effect of antioxidant treatment in rats with acute hemorrhagic pancreatitis

1994 • 68 citations

Adverse Effect of Therapeutic Vasoconstrictors in Experimental Acute Pancreatitis

1991 • 67 citations

Free radical inhibition and serial chemiluminescence in evolving experimental pancreatitis

1990 • 66 citations

Pancreatic microcirculation in acute pancreatitis

1998 • 63 citations

Effects of leukocyte and platelet depletion on ischemia-reperfusion injury to dog pancreas

1994 • 62 citations

Ischaemia—Reperfusion Mechanisms in Acute Pancreatitis

1996 • 62 citations

Role of platelet-activating factor in pancreatitis-associated acute lung injury in the rat.

1992 • 61 citations

Antioxidant and Calcium Channel Blockers Counteract Endothelial Barrier Injury Induced by Acute Pancreatitis in Rats

1995 • 58 citations

Intravenous Contrast Medium Impairs Oxygenation of the Pancreas in Acute Necrotizing Pancreatitis in the Rat

1994 • 58 citations

Determinants of Pancreatic Microcirculation in Acute Pancreatitis in Rats

1996 • 58 citations

IN VIVO FLUORESCENCE MICROSCOPY FOR THE ASSESSMENT OF MICROVASCULAR REPERFUSION INJURY IN SMALL BOWEL TRANSPLANTS IN RATS

1994 • 57 citations

Role of ischemia in acute pancreatitis

1992 • 57 citations

IT 9302, a synthetic interleukin-10 agonist, diminishes acute lung injury in rabbits with acute necrotizing pancreatitis

1998 • 57 citations

Intracellular Activation of Digestive Zymogens in Rat Pancreatic Acini

1991 • 56 citations

Endothelin Receptor Blockade Improves Fluid Sequestration, Pancreatic Capillary Blood Flow, and Survival in Severe Experimental Pancreatitis

1998 • 55 citations

Improvement of impaired pancreatic microcirculation by isovolemic hemodilution protects pancreatic morphology in acute biliary pancreatitis.

1993 • 52 citations

Experimental pancreatitis: Effect of plasma and dextran on pancreatic blood flow.

1978 • 51 citations

Protective effect of nitric oxide on development of acute pancreatitis in rats

1995 • 51 citations

ATTENUATION OF MICROVASCULAR REPERFUSION INJURY IN RAT PANCREAS TRANSPLANTATION BY L-ARGININE1

1999 • 50 citations

Early complement system activation and neutrophil priming in acute pancreatitis: Participation of trypsin

1997 • 49 citations

Ischemia and reperfusion in pancreas

1997 • 48 citations

Inhibition of platelet-activating factor, intercellular adhesion molecule 1 and platelet endothelial cell adhesion molecule 1 reduces experimental pancreatitis-associated gut endothelial barrier dysfunction

1999 • 48 citations

Microcirculation of the Normal and Inflamed Canine Pancreas

1975 • 46 citations

Does stress play a role in the development of severe pancreatitis in rats?

1990 • 45 citations

Effect of Endothelin-1 on the Development of Hemorrhagic Pancreatitis in Rats

1995 • 44 citations

Vascular factors in the pathogenesis of acute haemorrhagic pancreatitis.

1969 • 44 citations

Selective use of sandostatin in vascularized pancreas transplantation

1993 • 42 citations

Inhibition of bradykinin B₂receptor preserves microcirculation in experimental pancreatitis in rats

1998 • 42 citations

Low molecular weight dextran in experimental pancreatitis: Effects on pancreatic microcirculation

1983 • 41 citations

ET-1 Induces Pancreatitis-like Microvascular Deterioration and Acinar Cell Injury

1999 • 38 citations

Correlation of Pancreatic Blood Flow and High-Energy Phosphates during Experimental Pancreatitis

1982 • 36 citations

Mononuclear Phagocyte Activation and Acute Pancreatitis

1996 • 36 citations

Therapy for microcirculatory disorders in severe acute pancreatitis: comparison of delayed therapy with ICAM-1 antibodies and a specific endothelin a receptor antagonist

2000 • 34 citations

The Effect of Bile-induced Pancreatitis on the Intrapancreatic Vascular Pattern in Dogs

1969 • 33 citations

The Effect of Superoxide Dismutase on the Skin Microcirculation After Ischemia and Reperfusion

2015 • 33 citations

The Relative Safety of MRI Contrast Agent in Acute Necrotizing Pancreatitis

1998 • 32 citations

THE NITRIC OXIDE DONOR SODIUM NITROPRUSSIDE IS PROTECTIVE IN ISCHEMIA/REPERFUSION INJURY OF THE PANCREAS1

1998 • 31 citations

Platelet-Activating Factor

1996 • 31 citations

NITRIC OXIDE AND ARACHIDONATE METABOLISM IN ISCHEMIA-REPERFUSION ASSOCIATED WITH PANCREAS TRANSPLANTATION

1995 • 31 citations

The Effect of Gabexate Mesilate on Pancreatic and Hepatic Microcirculation in Acute Experimental Pancreatitis in Rats

1996 • 29 citations

The influence of ethanol on pancreatic blood flow in cats with chronic pancreatitis.

1992 • 27 citations

Circulating Mediators in Acute Pancreatitis as Predictors of Severity

1996 • 26 citations

Inhibition of neutrophil proteinases by recombinant serpin Lex032 reduces capillary no-reflow in ischemia/reperfusion-induced acute pancreatitis.

1999 • 26 citations

Endothelin-1 mediates the alcohol-induced reduction of pancreatic capillary blood flow

1998 • 26 citations

Structural alterations of pancreatic microvasculature in cerulein-induced pancreatitis in the rat

1990 • 26 citations

Somatostatin attenuates microcirculatory impairment in acute sodium taurocholate-induced pancreatitis.

1998 • 25 citations

Exocrine, but not endocrine, tissue is susceptible to microvascular ischemia/reperfusion injury following pancreas transplantation in the rat

1999 • 24 citations

The bradykinin antagonist CP-0597 can limit the progression of postischemic pancreatitis

1996 • 24 citations

Protease-Antiprotease Interactions and the Rationale for Therapeutic Protease Inhibitors

1996 • 24 citations

In Vivo Documentation of an Arteriovenous Shunt in Rat Pancreatic Acinar Tissue

1996 • 24 citations

Microvasculature of the Pancreas, Liver, and Kidney in Cerulein-Induced Pancreatitis

1993 • 23 citations

Pancreatic Blood Flow and Contrast Enhancement in Computed Tomography during Experimental Pancreatitis

1985 • 23 citations

Does Nitric Oxide Protect from Microcirculatory Disturbances in Experimental Acute Pancreatitis in Rats?

1996 • 22 citations

MICROCIRCULATORY DISTURBANCES OF THE PANCREAS IN CERULEIN-INDUCED ACUTE PANCREATITIS IN RATS WITH REFERENCE TO?-ARGININE, HEPARIN, AND PROCAINE TREATMENT

1997 • 20 citations

Effect of Ethanol on Pancreatic Interstitial pH and Blood Flow in Cats with Chronic Pancreatitis

1997 • 20 citations

Experimental ischemic pancreatitis: Treatment with albumin

1985 • 19 citations

A Novel Diamino-Pyridine Derivative Prevents Excessive Leukocyte Infiltration in Aggravation of Acute Necrotizing Pancreatitis

1999 • 19 citations

Detection of nitric oxide production and its role in pancreatic ischemia-reperfusion in rats

1996 • 18 citations

Contribution of pancreatic edema and short-term ischemia to experimental acute pancreatitis in the rat. I. Procedure and pathomorphological investigations.

1986 • 17 citations

Current views on the pathophysiology of acute biliary pancreatitis.

1995 • 17 citations

Release of Arachidonic Acid Metabolites during Acute Pancreatitis in Pigs

1989 • 17 citations

Platelet-Activating Factor Antagonist (TCV-309) Attenuates the Priming Effects of Bronchoalveolar Macrophages in Cerulein-Induced Pancreatitis Rats

1999 • 16 citations

Hypothesis: Vascular Compromise Is the Central Pathogenic Mechanism for Acute Hemorrhagic Pancreatitis

1995 • 15 citations

Oleic acid induced pancreatitis in pigs

1991 • 15 citations

Role of xanthine oxidase and eicosanoids in development of pancreatic ischemia-reperfusion injury

1995 • 14 citations

Pancreatic ischaemia; sensitivity and reversibility of the changes.

1975 • 14 citations

Ethanol causes vasoconstriction due to endothelin-1 release in rabbit gastric vessels

1991 • 13 citations

Pancreatic blood flow in experimental acute pancreatitis

1982 • 12 citations

Analysis of the Derangement of the Pancreatic Microcirculation in a Rat Caerulein Pancreatitis Model Using an Intravital Microscope System.

1996 • 11 citations

Blood flow and perfusion in acute haemorrhagic pancreatitis in the dog.

1986 • 11 citations

Pulmonary microvasculature in experimental acute haemorrhagic and oedematous pancreatitis

1991 • 10 citations

THE EFFECT OF A THROMBOXANE A2 RECEPTOR ANTAGONIST (ONO 3708) ON ISCHEMIA-REPERFUSION INJURY OF THE DOG PANCREAS

1994 • 10 citations

Acute pancreatitis after experimental pancreatic transplantation

1989 • 9 citations

Effects of hemorrhagic shock, aspirin, and ethanol on secretagogue-induced experimental pancreatitis

1990 • 9 citations

Nitric Oxide Enhances Endothelin Production in Pancreas Transplantation

1997 • 9 citations

Endothelin mediated nitric oxide effects in ischemia--reperfusion associated with pancreas transplantation.

1998 • 8 citations

Protective effects of prophylaxis with a protease inhibitor and a free radical scavenger against a temporary ischemia model of pancreatitis.

1995 • 8 citations

Die pankreasdurchblutung bei der experimentellen bili�ren pankreatitis

1990 • 8 citations

Hemorrhage induces arteriolar vasomotion and intermittent capillary perfusion in rat pancreas

1994 • 3 citations

Effects of Timing of Diatrizoate (Water-Soluble Contrast Medium) Administration on Pancreatic Microcirculatory Derangement in Cerulein Pancreatitis in Rats

2000 • 3 citations

[Oxygen radicals and acute pancreatitis].

1992 • 2 citations