CD14 is required for MyD88-independent LPS signaling

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

1998 • 7,541 citations

CD14, a Receptor for Complexes of Lipopolysaccharide (LPS) and LPS Binding Protein

1990 • 4,041 citations

Role of Adaptor TRIF in the MyD88-Independent Toll-Like Receptor Signaling Pathway

2003 • 3,104 citations

Unresponsiveness of MyD88-Deficient Mice to Endotoxin

1999 • 2,088 citations

Recognition of single-stranded RNA viruses by Toll-like receptor 7

2004 • 1,777 citations

Structure and Function of Lipopolysaccharide Binding Protein

1990 • 1,689 citations

Inferences, questions and possibilities in Toll-like receptor signalling

2004 • 1,458 citations

Identification of Lps2 as a key transducer of MyD88-independent TIR signalling

2003 • 1,226 citations

Essential role of MD-2 in LPS responsiveness and TLR4 distribution

2002 • 1,028 citations

TRAM is specifically involved in the Toll-like receptor 4–mediated MyD88-independent signaling pathway

2003 • 1,023 citations

Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4

2002 • 985 citations

CD36 is a sensor of diacylglycerides

2005 • 846 citations

The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors

2002 • 803 citations

Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide

2000 • 744 citations

Synthetic and natural Escherichia coli free lipid A express identical endotoxic activities

1985 • 488 citations

Physical contact between lipopolysaccharide and Toll-like receptor 4 revealed by genetic complementation

2000 • 432 citations

Toll-like receptor 3-mediated activation of NF-κB and IRF3 diverges at Toll-IL-1 receptor domain-containing adapter inducing IFN-β

2004 • 365 citations

Central role for type I interferons and Tyk2 in lipopolysaccharide-induced endotoxin shock

2003 • 357 citations

Genetic control of susceptibility to Salmonella typhimurium in mice: role of the LPS gene.

1980 • 356 citations

Identification of a Lipid A Binding Site in the Acute Phase Reactant Lipopolysaccharide Binding Protein

1989 • 351 citations

Crystal Structure of CD14 and Its Implications for Lipopolysaccharide Signaling

2005 • 273 citations

A family of lipopolysaccharide binding proteins involved in responses to gram-negative sepsis.

1988 • 224 citations

Endotoxic properties of chemically synthesized lipid A part structures. Comparison of synthetic lipid A precursor and synthetic analogues with biosynthetic lipid A precursor and free lipid A

1984 • 180 citations

Genetic control of resistance to infection in mice.

1982 • 106 citations