Physical contact between lipopolysaccharide and Toll-like receptor 4 revealed by genetic complementation

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

1998 • 7,541 citations

CD14, a Receptor for Complexes of Lipopolysaccharide (LPS) and LPS Binding Protein

1990 • 4,041 citations

Passive Immunization Against Cachectin/Tumor Necrosis Factor Protects Mice from Lethal Effect of Endotoxin

1985 • 2,380 citations

[68] Transcription maps of polyoma virus-specific RNA: Analysis by two-dimensional nuclease S1 gel mapping

1980 • 1,430 citations

Lipopolysaccharide (LPS)-binding protein accelerates the binding of LPS to CD14.

1994 • 747 citations

Lipid A-like molecules that antagonize the effects of endotoxins on human monocytes.

1991 • 425 citations

Macrophages as a source of tumoricidal activity (tumor-necrotizing factor)

1980 • 398 citations

Genetic and Physical Mapping of theLpsLocus: Identification of the Toll-4 Receptor as a Candidate Gene in the Critical Region

1998 • 372 citations

Monokine production by microglial cell clones

1989 • 366 citations

High-efficiency gene transfer and selection of human hematopoietic progenitor cells with a hybrid EBV/retroviral vector expressing the green fluorescence protein.

1998 • 357 citations

Genetic control of susceptibility to Salmonella typhimurium in mice: role of the LPS gene.

1980 • 356 citations

Requirement for lipopolysaccharide-responsive macrophages in galactosamine-induced sensitization to endotoxin

1986 • 340 citations

Detoxification of Bacterial Lipopolysaccharides (Endotoxins) by a Human Neutrophil Enzyme

1986 • 278 citations

Lipopolysaccharide (LPS) partial structures inhibit responses to LPS in a human macrophage cell line without inhibiting LPS uptake by a CD14-mediated pathway.

1992 • 273 citations

IL-1 induction-capacity of defined lipopolysaccharide partial structures.

1989 • 269 citations

Lipopolysaccharide binding protein and soluble CD14 catalyze exchange of phospholipids.

1997 • 232 citations

The Primary Role of Lymphoreticnlar Cells in the Mediation of Host Responses to Bacterial Endotoxim

1980 • 212 citations

Catalytic Properties of Lipopolysaccharide (LPS) Binding Protein

1996 • 198 citations

CD14 enhances cellular responses to endotoxin without imparting ligand-specific recognition.

1995 • 186 citations

Endotoxic properties of chemically synthesized lipid A part structures. Comparison of synthetic lipid A precursor and synthetic analogues with biosynthetic lipid A precursor and free lipid A

1984 • 180 citations

Enzymatically Deacylated Lipopolysaccharide (LPS) Can Antagonize LPS at Multiple Sites in the LPS Recognition Pathway

1995 • 143 citations

Lipopolysaccharide‐binding protein mediates CD14‐independent intercalation of lipopolysaccharide into phospholipid membranes

1996 • 123 citations

Analysis of Tlr4-Mediated LPS Signal Transduction in Macrophages by Mutational Modification of the Receptor

1999 • 114 citations

Genetic control of resistance to infection in mice.

1982 • 106 citations

Deacylated lipopolysaccharide inhibits neutrophil adherence to endothelium induced by lipopolysaccharide in vitro.

1987 • 96 citations

Alternative Cleavage of the Cachectin/Tumor Necrosis Factor Propeptide Results in a Larger, Inactive Form of Secreted Protein

1989 • 75 citations

Identification of lipopolysaccharide-binding proteins in 70Z/3 cells by photoaffinity cross-linking.

1990 • 68 citations

Structural and physicochemical requirements of endotoxins for the activation of arachidonic acid metabolism in mouse peritoneal macrophages in vitro

1989 • 61 citations

Retroviral immortalization of phagocytic and dendritic cell clones as a tool to investigate functional heterogeneity

1994 • 54 citations

Biological activities of analogues of lipid A based chemically on the revised structural model

1984 • 51 citations

Inhibition of endotoxin-induced interleukin-6 production by synthetic lipid A partial structures in human peripheral blood mononuclear cells

1991 • 50 citations

Mouse macrophage clones immortalized by retroviruses are functionally heterogeneous.

1991 • 38 citations

A comparison of the effects of intact and deacylated lipopolysaccharide on human polymorphonuclear leukocytes.

1990 • 34 citations

Generation of new oncogenic murine retroviruses by cotransfection of cloned AKR and MH2 proviruses.

1989 • 20 citations

Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxin. Science, 1985, 229(4716):869-871. Classical article.

2008 • 18 citations

Comparative Study of Lipopolysaccharide-, Lipid IVa-, and Lipid X-Induced Tumor Necrosis Factor Production in Murine Macrophage-Like Cell Lines

1990 • 9 citations

Analysis of Tlr4-Mediated LPS Signal Transduction in Macrophages by Mutational Modification of the Receptor

2000 • 8 citations

Lipopolysaccharide Preparations in Aqueous Media: Implications for Solution Versus Suspension

2020 • 2 citations