Overview of Protein Aggregation in Single, Double, and Triple Neurodegenerative Brain Amyloidoses

Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases

2002 • 2,424 citations

Amyloid deposition as the central event in the aetiology of Alzheimer's disease

1991 • 2,375 citations

Oxidative Stress Hypothesis in Alzheimer's Disease

1997 • 2,355 citations

Oxidative Damage Linked to Neurodegeneration by Selective α-Synuclein Nitration in Synucleinopathy Lesions

2000 • 1,526 citations

Unfolding the role of protein misfolding in neurodegenerative diseases

2003 • 1,411 citations

Amyloid, the presenilins and Alzheimer's disease

1997 • 1,370 citations

Chaperone Suppression of α-Synuclein Toxicity in a Drosophila Model for Parkinson's Disease

2002 • 1,220 citations

Toxic Proteins in Neurodegenerative Disease

2002 • 1,202 citations

Initiation and Synergistic Fibrillization of Tau and Alpha-Synuclein

2003 • 830 citations

Alzheimer's disease – do tauists and baptists finally shake hands?

2002 • 504 citations

Excitotoxic and Excitoprotective Mechanisms: Abundant Targets for the Prevention and Treatment of Neurodegenerative Disorders

2003 • 469 citations

Modification of Brain Aging and Neurodegenerative Disorders by Genes, Diet, and Behavior

2002 • 436 citations

Treatment of Alzheimer's Disease

1999 • 382 citations

Genetic dissection of Alzheimer's disease and related dementias: amyloid and its relationship to tau

1998 • 336 citations

The relationship between oxidative/nitrative stress and pathological inclusions in Alzheimer’s and Parkinson’s diseases1,2 11Guest Editors: Mark A. Smith and George Perry 22This article is part of a series of reviews on “Causes and Consequences of Oxidative Stress in Alzheimer’s Disease.” The full list of papers may be found on the homepage of the journal.

2002 • 277 citations

Chaperoning brain degeneration

2002 • 208 citations

“Fatal Attractions” of Proteins: A Comprehensive Hypothetical Mechanism Underlying Alzheimer's Disease and Other Neurodegenerative Disorders

2000 • 181 citations

Parkinson's Disease and Related α‐Synucleinopathies Are Brain Amyloidoses

2003 • 144 citations

Chaperoning brain diseases

1998 • 82 citations

Alzheimer Disease Therapeutics

2001 • 49 citations

“Emerging Alzheimer’s disease therapies: focusing on the future”

2002 • 37 citations

Application of Chemical Chaperones to the Rescue of Folding Defects

2003 • 5 citations