Overexpression of B-type cyclins alters chromosomal segregation

Transformation of intact yeast cells treated with alkali cations

1983 • 7,688 citations

Genetic instabilities in human cancers

1998 • 4,165 citations

Genetic instability in colorectal cancers

1997 • 1,989 citations

Mutations of mitotic checkpoint genes in human cancers

1998 • 1,482 citations

Regulatable promoters of Saccharomyces cerevisiae: comparison of transcriptional activity and their use for heterologous expression

1994 • 968 citations

Isolation of a human cyclin cDNA: Evidence for cyclin mRNA and protein regulation in the cell cycle and for interaction with p34cdc2

1989 • 920 citations

Identification of a Vertebrate Sister-Chromatid Separation Inhibitor Involved in Transformation and Tumorigenesis

1999 • 801 citations

MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells

2001 • 727 citations

Mutations in the APC tumour suppressor gene cause chromosomal instability

2001 • 722 citations

Deregulated cyclin E induces chromosome instability

1999 • 692 citations

A role for the Adenomatous Polyposis Coli protein in chromosome segregation

2001 • 553 citations

Cohesin Cleavage by Separase Required for Anaphase and Cytokinesis in Human Cells

2001 • 490 citations

Translation of cyclin mRNA is necessary for extracts of activated Xenopus eggs to enter mitosis

1989 • 438 citations

The spindle checkpoint

1999 • 408 citations

The A- and B-type cyclin associated cdc2 kinases in Xenopus turn on and off at different times in the cell cycle.

1990 • 377 citations

APCCdc20 promotes exit from mitosis by destroying the anaphase inhibitor Pds1 and cyclin Clb5

1999 • 346 citations

Overexpression of cyclin B1 in early-stage non-small cell lung cancer and its clinical implication.

2000 • 292 citations

Cyclin B2-null mice develop normally and are fertile whereas cyclin B1-null mice die in utero

1998 • 285 citations

Budding Yeast SKP1 Encodes an Evolutionarily Conserved Kinetochore Protein Required for Cell Cycle Progression

1996 • 284 citations

Human cyclins B1 and B2 are localized to strikingly different structures: B1 to microtubules, B2 primarily to the Golgi apparatus.

1995 • 261 citations

Expression of pituitary-tumour transforming gene in colorectal tumours

2000 • 229 citations

Characterization of MAD2B and Other Mitotic Spindle Checkpoint Genes

1999 • 215 citations

NF-Y Mediates the Transcriptional Inhibition of thecyclin B1, cyclin B2, and cdc25CPromoters upon Induced G2 Arrest

2001 • 169 citations

The Localization of Human Cyclins B1 and B2 Determines Cdk1 Substrate Specificity and Neither Enzyme Requires Mek to Disassemble the Golgi Apparatus

2001 • 136 citations

Overexpression of cyclin B1 in human colorectal cancers

1997 • 127 citations

Mutations in the mitotic check point gene, MAD1L1, in human cancers

2001 • 116 citations

Ctf19p: A Novel Kinetochore Protein in Saccharomyces cerevisiae and a Potential Link between the Kinetochore and Mitotic Spindle

1999 • 106 citations

Inverse regulation of cyclin B1 by c-Myc and p53 and induction of tetraploidy by cyclin B1 overexpression.

2001 • 86 citations

[22] Visual assay for chromosome ploidy

1987 • 67 citations

Meiosis-specific cell cycle regulation in maturing Xenopus oocytes

1994 • 58 citations

Clb5-associated Kinase Activity is Required Early in the Spindle Pathway for Correct Preanaphase Nuclear Positioning in Saccharomyces cerevisiae

1998 • 48 citations

Requirement of cyclin B2, but not cyclin B1, for bipolar spindle formation in frog (Rana japonica) oocytes

2001 • 31 citations