T‐Cell Responses and Tolerance to Mlsa Determinants

MHC-Restricted Cytotoxic T Cells: Studies on the Biological Role of Polymorphic Major Transplantation Antigens Determining T-Cell Restriction-Specificity, Function, and Responsiveness

1979 • 1,969 citations

Self-tolerance eliminates T cells specific for Mls-modified products of the major histocompatibility complex

1988 • 1,036 citations

T-cell receptor Vβ use predicts reactivity and tolerance to Mlsa- encoded antigens

1988 • 901 citations

Cellular Mechanisms of Immunologic Tolerance

1983 • 521 citations

Differences in antigen presentation to MHC class I-and class II-restricted influenza virus-specific cytolytic T lymphocyte clones.

1986 • 513 citations

The T-cell repertoire is heavily influenced by tolerance to polymorphic self-antigens

1988 • 491 citations

A T cell receptor Vβ segment that imparts reactivity to a class II major histocompatibility complex product

1987 • 408 citations

Function and Specificity of T Cell Subsets in the Mouse

1987 • 208 citations

Thymocytes appear to ignore class I major histocompatibility complex antigens expressed on thymus epithelial cells

1984 • 158 citations

STUDIES OF THE ROLE OF THE THYMIC ENVIRONMENT IN THE INDUCTION OF TOLERANCE TO MHC ANTIGENS

1985 • 127 citations

Unusual phenotype of B cells in the thymus of normal mice.

1988 • 127 citations

Preferential expression of the T-cell receptor Vβ3 gene by Mlsc reactive T cells

1988 • 123 citations

Antigen Presentation by B Cells and Its Significance in T-B Interactions

1986 • 119 citations

Self-tolerance alters T-cell receptor expression in an antigen-specific MHC restricted immune response

1988 • 101 citations

T lymphocytes responding to Mls-locus antigens are Lyt-1+, 2− andI-A restricted

1980 • 99 citations

Expression of M locus differences by B cells but not T cells

1974 • 97 citations

Restricted tissue distribution of Mlsa determinants. Stimulation of Mlsa-reactive T cells by B cells but not by dendritic cells or macrophages.

1989 • 90 citations

The immunobiology of the T cell response to Mls-locus-disparate stimulator cells. I. Unidirectionality, new strain combinations, and the role of Ia antigens.

1985 • 85 citations

Enumeration of IL 2-secreting helper T cells by limiting dilution analysis, and demonstration of unexpectedly high levels of IL 2 production per responding cell.

1982 • 77 citations

Specific lymphocyte-activating determinants expressed on mouse macrophages

1975 • 67 citations

The immunobiology of T cell responses to Mls-locus-disparate stimulator cells. II. Effects of Mls-locus-disparate stimulator cells on cloned, protein antigen-specific, Ia-restricted T cell lines.

1985 • 65 citations

T cell clones with dual specificity for M1s and various major histocompatibility complex determinants.

1981 • 60 citations

T cell responses to Mls determinants are restricted by cross-reactive MHC determinants.

1985 • 60 citations

Absence of H-2 restriction in primary and secondary mixed-lymphocyte reactions to strong M1s determinants.

1980 • 57 citations

Capacity of small B cell‐enriched populations to stimulate mixed lymphocyte reactions: marked differences between irradiated vs. mitomycin C‐treated stimulators

1985 • 51 citations

T Cell Function in Bone Marrow Chimeras; Absence of Host‐Reactive T Cells and Cooperation of Helper T Cells across Allogeneic Barriers

1976 • 49 citations

T cell recognition in the mixed lymphocyte response. II. Ia-positive splenic adherent cells are required for non-I region-induced stimulation.

1981 • 36 citations

Mls is not a single gene, allelic system. Different stimulatory Mls determinants are the products of at least two nonallelic, unlinked genes.

1987 • 35 citations

Specific neonatally induced tolerance to Mls locus determinants.

1985 • 29 citations

STUDIES ON NON‐H‐2 LINKED LYMPHOCYTE ACTIVATING DETERMINANTS I. DESCRIPTION OF THE CELL TYPE BEARING THE MLS PRODUCT

1977 • 27 citations

T cell receptors for responses to Mls determinants and allo-H-2 determinants appear to be encoded on different chromosomes.

1985 • 24 citations

Parameters Involved in the Induction and Abrogation of the Lethal Graft‐versus‐Host Reaction Directed against non‐H‐2 Antigens

1985 • 20 citations

Independent inhibition of IL 2 synthesis and cell proliferation by anti‐Ia antibodies in mixed lymphocyte responses to Mls

1984 • 19 citations

Stimulator requirements for primed alloreactive T cells: Macrophages and dendritic cells activate T cells across all genetic disparities

1985 • 18 citations

T Cells with Multiple Specificities

1986 • 18 citations

ANALYSIS OF UNEXPECTED INHIBITIONS OF T LYMPHOCYTE PROLIFERATION TO SOLUBLE ANTIGEN, ALLOANTIGEN AND MITOGEN BY UNFRAGMENTED ANTI‐I‐A^k OR ANTI‐I‐E/C^k MONOCLONAL ANTIBODIES

1982 • 18 citations

Immunologic effects of whole-body ultraviolet (uv) irradiation

1981 • 15 citations

THE Mls LOCUS: PAST, PRESENT AND FUTURE

1988 • 4 citations

Mls DETERMINANTS AND ANTI‐Mls RECEPTORS

1988 • 2 citations

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