Enduring cognitive, neurobehavioral and histopathological changes persist for up to one year following severe experimental brain injury in rats

Developments of a water-maze procedure for studying spatial learning in the rat

1984 • 6,896 citations

A new model of diffuse brain injury in rats

1994 • 1,177 citations

Traumatic brain injury in the rat: Characterization of a lateral fluid-percussion model

1989 • 1,126 citations

Selective vulnerability of dentate hilar neurons following traumatic brain injury: a potential mechanistic link between head trauma and disorders of the hippocampus

1992 • 680 citations

Head Trauma as a Risk Factor for Alzheimer's Disease: A Collaborative Re-Analysis of Case-Control Studies

1991 • 582 citations

Dynamic changes in local cerebral glucose utilization following cerebral concussion in rats: evidence of a hyper- and subsequent hypometabolic state

1991 • 571 citations

Beta amyloid protein deposition in the brain after severe head injury: implications for the pathogenesis of Alzheimer's disease.

1994 • 563 citations

β-Amyloid precursor protein (βAPP) as a marker for axonal injury after head injury

1993 • 557 citations

DELAYED RECOVERY OF INTELLECTUAL FUNCTION AFTER MINOR HEAD INJURY

1974 • 554 citations

The occult aftermath of boxing.

1990 • 522 citations

Evidence of apoptotic cell death after experimental traumatic brain injury in the rat.

1995 • 517 citations

Use-dependent growth of pyramidal neurons after neocortical damage

1994 • 513 citations

βA4 amyloid protein deposition in brain after head trauma

1991 • 465 citations

Stalning af amyloid percursor protein to study axonal damage in mild head Injury

1994 • 456 citations

Experimental fluid percussion brain injury: vascular disruption and neuronal and glial alterations

1989 • 450 citations

Moderate Head Injury: Completing the Clinical Spectrum of Brain Trauma

1982 • 438 citations

Progressive Atrophy and Neuron Death for One Year Following Brain Trauma in the Rat

1997 • 431 citations

Prolonged memory impairment in the absence of hippocampal cell death following traumatic brain injury in the rat

1990 • 411 citations

Inflammatory leukocytic recruitment and diffuse neuronal degeneration are separate pathological processes resulting from traumatic brain injury

1995 • 375 citations

Mild Experimental Brain Injury in the Rat Induces Cognitive Deficits Associated with Regional Neuronal Loss in the Hippocampus

1993 • 359 citations

Early Microvascular and Neuronal Consequences of Traumatic Brain Injury: A Light and Electron Microscopic Study in Rats

1994 • 357 citations

Evaluation of Memory Dysfunction Following Experimental Brain Injury Using the Morris Water Maze

1991 • 352 citations

Overgrowth and pruning of dendrites in adult rats recovering from neocortical damage

1992 • 349 citations

Cognitive Deficits Following Traumatic Brain Injury Produced by Controlled Cortical Impact

1992 • 348 citations

Early detection of axonal injury after human head trauma using immunocytochemistry for ?-amyloid precursor protein

1994 • 348 citations

Neurobehavioral outcome 1 year after severe head injury

1990 • 320 citations

Temporal and spatial characterization of neuronal injury following lateral fluid-percussion brain injury in the rat

1996 • 289 citations

Neuropsychiatric sequelae of head injuries.

1992 • 248 citations

Immunohistochemical characterization of alterations in the distribution of amyloid precursor proteins and beta-amyloid peptide after experimental brain injury in the rat

1996 • 242 citations

Prolonged Calpain-mediated Spectrin Breakdown Occurs Regionally Following Experimental Brain Injury in the Rat

1996 • 235 citations

Traumatic Brain Injury in the Rat: Characterization of a Midline Fluid-Percussion Model

1987 • 224 citations

Re-examination of ex-boxers' brains using immunohistochemistry with antibodies to amyloid ?-protein and tau protein

1991 • 200 citations

Neuropsychiatry Sequelae of Head Injuries

1992 • 189 citations

Neural damage in the rat thalamus after cortical infarcts.

1990 • 186 citations

Learning and memory

1977 • 183 citations

Alterations in Regional Cerebral Blood Flow following Brain Injury in the Rat

1991 • 175 citations

Distribution of β‐amyloid protein in the brain following severe head injury

1995 • 145 citations

Enduring suppression of hippocampal long-term potentiation following traumatic brain injury in rat

1992 • 138 citations

Thalamic retrograde degeneration following cortical injury: An excitotoxic process?

1990 • 127 citations

Long-term outcome after severe head injury.

1979 • 121 citations

Penetrating head injury in young adulthood exacerbates cognitive decline in later years

1989 • 120 citations

Development of Prolonged Focal Cerebral Edema and Regional Cation Changes Following Experimental Brain Injury in the Rat

1992 • 120 citations

Neurofibrillary tangles, but not Alzheimer‐type pathology, in a young boxer

1996 • 114 citations

Persistent memory dysfunction is associated with bilateral hippocampal damage following experimental brain injury

1994 • 109 citations

Learning and memory

1991 • 101 citations

Temporal response and effects of excitatory amino acid antagonism on microtubule-associated protein 2 immunoreactivity following experimental brain injury in rats

1995 • 98 citations

Changes in Cellular Bioenergetic State Following Graded Traumatic Brain Injury in Rats: Determination by Phosphorus 31 Magnetic Resonance Spectroscopy

1988 • 97 citations

Widespread Metabolic Depression and Reduced Somatosensory Circuit Activation Following Traumatic Brain Injury in Rats

1994 • 92 citations

Traumatic brain injury in rat produces changes of β-amyloid precursor protein immunoreactivity

1995 • 90 citations

Nerve Growth Factor Administration Attenuates Cognitive but Not Neurobehavioral Motor Dysfunction or Hippocampal Cell Loss Following Fluid‐Percussion Brain Injury in Rats

1995 • 90 citations

Chapter 16 Molecular pathology of head trauma: altered βAPP metabolism and the aetiology of Alzheimer's disease

1993 • 89 citations

Evaluation of a novel calcium channel blocker, (S)-emopamil, on regional cerebral edema and neurobehavioral function after experimental brain injury

1992 • 81 citations

Biochemical and histological alterations induced by fluid percussion brain injury in the rat

1993 • 69 citations

Dyscalculia and Dyslexia After Right Hemisphere Injury in Infancy

1996 • 60 citations

Traumatic Brain Injury, Aging and Reaction Time

1989 • 45 citations

The Effect of Traumatic Brain Injury on the Visual System: A Morphologic Characterization of Reactive Axonal Change

1988 • 44 citations

Short-Term Recognition Memory in Relation to Severity of Head Injury

1976 • 39 citations

The nootropic compound BMY-21502 improves spatial learning ability in brain injured rats

1993 • 33 citations

βAP deposition and head trauma

1996 • 20 citations

Placebo-controlled study of pramiracetam in young males with memory and cognitive problems resulting from head injury and anoxia

1991 • 19 citations

Development of Brain Edema Following Fluid Percussion Injury

1985 • 9 citations