Mild Pre- and Posttraumatic Hypothermia Attenuates Blood-Brain Barrier Damage Following Controlled Cortical Impact Injury in the Rat

Small Differences in Intraischemic Brain Temperature Critically Determine the Extent of Ischemic Neuronal Injury

1987 • 1,821 citations

A controlled cortical impact model of traumatic brain injury in the rat

1991 • 1,123 citations

Central nervous systems trauma and strokeI. Biochemical considerations for oxygen radical formation and lipid peroxidation

1989 • 626 citations

Cerebral Blood Flow and Cerebral Oxygen Consumption During Hypothermia

1954 • 560 citations

A Phase II Study of Moderate Hypothermia in Severe Brain Injury

1993 • 546 citations

The use of moderate therapeutic hypothermia for patients with severe head injuries: a preliminary report

1993 • 534 citations

Marked Protection by Moderate Hypothermia after Experimental Traumatic Brain Injury

1991 • 529 citations

The effect of mild hyperthermia and hypothermia on brain damage following 5, 10, and 15 minutes of forebrain ischemia

1990 • 409 citations

The Importance of Brain Temperature in Alterations of the Blood-Brain Barrier Following Cerebral Ischemia

1990 • 373 citations

Post-traumatic brain hypothermia reduces histopathological damage following concussive brain injury in the rat

1994 • 304 citations

THE EFFECT OF INDUCED HYPOTHERMIA UPON OXYGEN CONSUMPTION IN THE RAT BRAIN

1975 • 268 citations

Mild Intraischemic Hypothermia Reduces Postischemic Hyperperfusion, Delayed Postischemic Hypoperfusion, Blood-Brain Barrier Disruption, Brain Edema, and Neuronal Damage Volume after Temporary Focal Cerebral Ischemia in Rats

1994 • 245 citations

The Effects of Anesthesia and Hypothermia on Canine Cerebral ATP and Lactate during Anoxia Produced by Decapitation

1970 • 237 citations

Brain Hydroxyl Radical Generation in Acute Experimental Head Injury

1993 • 226 citations

Moderate hypothermia reduces blood-brain barrier disruption following traumatic brain injury in the rat

1992 • 207 citations

Direct Measurement of Hydroxyl Radicals, Lipid Peroxidation, and Blood–Brain Barrier Disruption Following Unilateral Cortical Impact Head Injury in the Rat

1994 • 195 citations

Protective effects of brain hypothermia on behavior and histopathology following global cerebral ischemia in rats

1992 • 180 citations

Reduced cerebral blood flow, oxygen delivery, and electroencephalographic activity after traumatic brain injury and mild hemorrhage in cats

1992 • 129 citations

Experimental head injury in the rat

1977 • 123 citations

Causes and effects of systemic complications among severely head injured patients transferred to a neurosurgical unit.

1992 • 105 citations

The effects of hypovolemic hypotension on high-energy phosphate metabolism of traumatized brain in rats

1988 • 89 citations

Conditions for pharmacologic evaluation in the gerbil model of forebrain ischemia.

1989 • 87 citations

Experimental head injury in the rat

1977 • 78 citations

Rate of cerebral energy consumption in concussive head injury in the rat

1977 • 59 citations

Post-traumatic brain hypothermia reduces histopathological damage following concussive brain injury in the rat

1994 • 57 citations

Magnetic Resonance Imaging and ³¹P Magnetic Resonance Spectroscopy Study of the Effect of Temperature on Ischemic Brain Injury

1992 • 37 citations

Protective efficacy of a hypothermic pharmacological agent in gerbil forebrain ischemia.

1993 • 31 citations

Rate of cerebral ATP utilization in rats

1960 • 31 citations

The relationship between traumatic brain injury-induced changes in brain temperature and behavioral and anatomical outcome

1994 • 27 citations