Diverse Effects of the Guanine Nucleotide Exchange Factor RCC1 on RNA Transport

The GTP-binding protein Ran/TC4 is required for protein import into the nucleus

1993 • 760 citations

Monoclonal antibodies to nucleic acid-containing cellular constituents: probes for molecular biology and autoimmune disease.

1981 • 725 citations

Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1

1991 • 703 citations

Inhibition of nuclear protein import by nonhydrolyzable analogues of GTP and identification of the small GTPase Ran/TC4 as an essential transport factor [published erratum appears in J Cell Biol 1994 Jan;124(1-2):217]

1993 • 544 citations

RanGAP1 induces GTPase activity of nuclear Ras-related Ran.

1994 • 526 citations

The RCC1 protein, a regulator for the onset of chromosome condensation locates in the nucleus and binds to DNA.

1989 • 367 citations

Structure and Function of Major and Minor Small Nuclear Ribonucleoprotein Particles

1988 • 363 citations

Translocation of RNA-coated gold particles through the nuclear pores of oocytes.

1988 • 292 citations

Characterization of Four Novel ras-Like Genes Expressed in a Human Teratocarcinoma Cell Line

1990 • 285 citations

Characterization of proteins that interact with the cell-cycle regulatory protein Ran/TC4

1993 • 261 citations

Premature chromosome condensation in a ts DNA-mutant of BHK cells

1978 • 260 citations

A precursor of globin messenger RNA

1976 • 254 citations

Translocation of a specific premessenger ribonucleoprotein particle through the nuclear pore studied with electron microscope tomography

1992 • 254 citations

Monoclonal autoantibody from a (new zealand black x new zealand white)F₁ mouse and some human scleroderma sera target an MT_r 34,000 nucleolar protein of the U3 RNP particle

1987 • 252 citations

Structure and Function of the Nuclear Pore Complex

1992 • 237 citations

Loss of RCC1, a nuclear DNA-binding protein, uncouples the completion of DNA replication from the activation of cdc2 protein kinase and mitosis.

1991 • 195 citations

RCC1 in the cell cycle: the regulator of chromosome condensation takes on new roles

1993 • 192 citations

Regulation of RNA processing and transport by a nuclear guanine nucleotide release protein and members of the Ras superfamily.

1993 • 183 citations

The GTP-bound form of the yeast Ran/TC4 homologue blocks nuclear protein import and appearance of poly(A)+ RNA in the cytoplasm.

1995 • 170 citations

The nuclear pore complex

1993 • 166 citations

Cell Biology of the snRNP Particle

1990 • 163 citations

A G protein involved in nucleocytoplasmic transport: the role of Ran

1994 • 159 citations

A yeast mutant, PRP20, altered in mRNA metabolism and maintenance of the nuclear structure, is defective in a gene homologous to the human gene RCC1 which is involved in the control of chromosome condensation

1990 • 152 citations

Nuclear PRP20 protein is required for mRNA export.

1993 • 148 citations

GSP1 and GSP2, genetic suppressors of the prp20-1 mutant in Saccharomyces cerevisiae: GTP-binding proteins involved in the maintenance of nuclear organization.

1993 • 145 citations

Evidence for channeled diffusion of pre-mRNAs during nuclear RNA transport in metazoans.

1993 • 144 citations

Purification of snRNPs U1, U2, U4, U5 and U6 with 2,2,7-trimethylguanosine-specific antibody and definition of their constituent proteins reacting with anti-Sm and anti-(U1)RNP antisera.

1983 • 143 citations

Defects in mRNA 3'-end formation, transcription initiation, and mRNA transport associated with the yeast mutation prp20: possible coupling of mRNA processing and chromatin structure.

1992 • 142 citations

The nucleolar snRNAs: catching up with the spliceosomal snRNAs

1993 • 141 citations

The subnuclear localization of tRNA ligase in yeast.

1987 • 133 citations

Retention and 5′ Cap Trimethylation of U3 snRNA in the Nucleus

1994 • 108 citations

Messenger RNA turnover in cell-free extracts

1990 • 101 citations

Transport of RNA between nucleus and cytoplasm

1992 • 93 citations

Nucleocytoplasmic transport and processing of small nuclear RNA precursors.

1990 • 90 citations

RNA travel: Tracks from DNA to cytoplasm

1993 • 82 citations

Intracellular distribution of low molecular weight RNA species in HeLa cells.

1980 • 81 citations

Reconstitution of the U1 small nuclear ribonucleoprotein particle.

1987 • 72 citations

Nuclear mRNA export

1991 • 69 citations

Structure and function of nucleolar snRNPs

1993 • 62 citations

Antibody-nucleic acid complexes. Immunospecific retention of globin mRNA with antibodies specific for 7-methylguanosine

1982 • 42 citations

Rapid Inhibition of Processing and Assembly of Small Nuclear Ribonucleoproteins after Infection with Vesicular Stomatitis Virus

1987 • 39 citations

mRNA nuclear export

1994 • 38 citations

Accurate and efficient 3' processing of U2 small nuclear RNA precursor in a fractionated cytoplasmic extract.

1987 • 33 citations

Cytoplasmic maturation of the snRNAs

1987 • 21 citations

Viral transcription is necessary and sufficient for vesicular stomatitis virus to inhibit maturation of small nuclear ribonucleoproteins

1989 • 11 citations