Studies on the mechanisms of action of picrotoxin, quercetin and pregnanolone at the GABAρ1 receptor
Data up to Jan 2025
Total Citations Per Year
Abstract
References (54)
GABAA Receptor Channels
1994 • 1,948 citations
International Union of Pharmacology. XV. Subtypes of gamma-aminobutyric acidA receptors: classification on the basis of subunit structure and receptor function.
1998 • 1,204 citations
Which GABAA-receptor subtypes really occur in the brain?
1996 • 1,183 citations
Neurosteroids: Endogenous bimodal modulators of the GABAA receptor mechanism of action and physiological significance
1992 • 1,098 citations
Structure-activity relationships for steroid interaction with the gamma-aminobutyric acidA receptor complex.
1987 • 601 citations
International Union of Pharmacology. XXXIII. Mammalian gamma -Aminobutyric AcidB Receptors: Structure and Function
2002 • 588 citations
GABA receptor mechanisms in the central nervous system
1991 • 555 citations
Constructing inhibitory synapses
2001 • 467 citations
Cloning of the gamma-aminobutyric acid (GABA) rho 1 cDNA: a GABA receptor subunit highly expressed in the retina.
1991 • 426 citations
THE ‘ABC’ OF GABA RECEPTORS: A BRIEF REVIEW
1999 • 423 citations
Pharmacology of GABA receptor CI− channels in rat retinal bipolar cells
1993 • 353 citations
Mechanism of memantine block of NMDA‐activated channels in rat retinal ganglion cells: uncompetitive antagonism.
1997 • 275 citations
Generating diversity at GAB Aergic synapses
2001 • 253 citations
GABAc receptors
1995 • 243 citations
GABAC receptors: relatively simple transmitter-gated ion channels?
1996 • 236 citations
Expression of mammalian gamma-aminobutyric acid receptors with distinct pharmacology in Xenopus oocytes.
1991 • 202 citations
gamma-Aminobutyric acid A or C receptor? gamma-Aminobutyric acid rho 1 receptor RNA induces bicuculline-, barbiturate-, and benzodiazepine-insensitive gamma-aminobutyric acid responses in Xenopus oocytes.
1992 • 201 citations
Cloning of a gamma-aminobutyric acid type C receptor subunit in rat retina with a methionine residue critical for picrotoxinin channel block.
1995 • 197 citations
On the mechanism of action of picrotoxin on GABA receptor channels in dissociated sympathetic neurones of the rat.
1992 • 193 citations
Characterization of bicuculline/baclofen-insensitive (rho-like) gamma-aminobutyric acid receptors expressed in Xenopus oocytes. II. Pharmacology of gamma-aminobutyric acidA and gamma-aminobutyric acidB receptor agonists and antagonists.
1993 • 177 citations
Design and in vitro pharmacology of a selective gamma-aminobutyric acidC receptor antagonist.
1996 • 174 citations
Expression of GABA Receptor ρ1 and ρ2 Subunits in the Retina and Brain of the Rat
1995 • 163 citations
Temporal Contrast Enhancement via GABAC Feedback at Bipolar Terminals in the Tiger Salamander Retina
1998 • 155 citations
Structure and function of GABAC receptors: a comparison of native versus recombinant receptors
2001 • 155 citations
Multiple mechanisms of picrotoxin block of GABA‐induced currents in rat hippocampal neurons.
1993 • 144 citations
Interaction of picrotoxin with GABAA receptor channel-lining residues probed in cysteine mutants
1995 • 143 citations
Point mutations in the M2 region of the alpha, beta, or gamma subunit of the GABAA channel that abolish block by picrotoxin.
1995 • 142 citations
Homomeric rho 1 GABA channels: activation properties and domains.
1994 • 139 citations
Molecular composition of GABAC receptors
1998 • 131 citations
Differential pharmacology of GABAA and GABAC receptors on rat retinal bipolar cells
1994 • 130 citations
Elimination of the ρ1 Subunit Abolishes GABACReceptor Expression and Alters Visual Processing in the Mouse Retina
2002 • 126 citations
Flavonoid modulation of ionic currents mediated by GABAA and GABAC receptors
2003 • 120 citations
Pharmacology of novel GABA receptors found on rod horizontal cells of the white perch retina
1994 • 119 citations
Channel opening locks agonist onto the GABAC receptor
1999 • 115 citations
Site-specific fluorescence reveals distinct structural changes with GABA receptor activation and antagonism
2002 • 104 citations
A novel gamma-aminobutyric acid receptor subunit (rho 2) cloned from human retina forms bicuculline-insensitive homooligomeric receptors in Xenopus oocytes
1994 • 102 citations
A single amino acid in gamma-aminobutyric acid rho 1 receptors affects competitive and noncompetitive components of picrotoxin inhibition.
1995 • 92 citations
GABA ρ2 receptor pharmacological profile: GABA recognition site similarities to ρ1
1993 • 83 citations
Effects of steroids on gamma-aminobutyric acid receptors expressed in Xenopus oocytes by poly(A)+ RNA from mammalian brain and retina.
1992 • 81 citations
Agonist Trapping by GABAAReceptor Channels
2001 • 75 citations
Studies on the mechanism of action of picrotoxinin and other convulsants at the crustacean muscle GABA receptor
1986 • 74 citations
Substitutions of the Highly Conserved M2 Leucine Create Spontaneously Opening ρ1 γ-Aminobutyric Acid Receptors
1998 • 73 citations
Disinhibition in Rat Superior Colliculus Mediated by GABACReceptors
2001 • 69 citations
Characterization of bicuculline/baclofen-insensitive gamma-aminobutyric acid receptors expressed in Xenopus oocytes. I. Effects of Cl- channel inhibitors.
1992 • 61 citations
Differential modulation of the gamma-aminobutyric acid type C receptor by neuroactive steroids.
1999 • 60 citations
5β-Pregnan-3β-ol-20-one, a specific antagonist at the neurosteroid site of the GABAA receptor-complex
1992 • 58 citations
Permeability and single channel conductance of human homomeric ρ1 GABAC receptors
1999 • 51 citations
Localization of GABA receptor rho 2 and rho 3 subunits in rat brain and functional expression of homooligomeric rho 3 receptors and heterooligomeric rho 2 rho 3 receptors.
1999 • 45 citations
Multireceptor GABAergic regulation of synaptic communication in amphibian retina
2001 • 43 citations
Zinc downmodulates thf GABAc receptor current in cone horizontal cells acutely isolated from the catfish retina
1995 • 42 citations
Agonist-induced closure of constitutively open γ-aminobutyric acid channels with mutated M2 domains
1997 • 41 citations
Localization of γ-aminobutyric acid (GABA) receptor ρ3 subunit in rat retina
1997 • 30 citations
Use-dependent and Use-independent blocking actions of picrotoxin and zinc at the GABAC receptor in retinal horizontal cells
1996 • 26 citations
GABA-Induced Chloride Current in Catfish Horizontal Cells Mediated by Non-GABAA Receptor Channels.
1995 • 19 citations