Chronic Pain Induces Anxiety with Concomitant Changes in Opioidergic Function in the Amygdala

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

The rat brain in stereotaxic coordinates

1983 • 28,962 citations

PHARMACOLOGICAL EFFECTS PRODUCED BY INTRACEREBRAL INJECTION OF DRUGS IN THE CONSCIOUS MOUSE

1957 • 1,523 citations

Opioid-receptor mRNA expression in the rat CNS: anatomical and functional implications

1995 • 1,267 citations

Cloning of a Delta Opioid Receptor by Functional Expression

1992 • 1,225 citations

Anatomy of CNS opioid receptors

1988 • 1,178 citations

Regional Mu Opioid Receptor Regulation of Sensory and Affective Dimensions of Pain

2001 • 832 citations

Psychotomimesis Mediated by κ Opiate Receptors

1986 • 822 citations

Molecular cloning and functional expression of a mu opioid receptor from rat brain

1994 • 805 citations

Neurotransmission in the rat amygdala related to fear and anxiety

1994 • 781 citations

Mice deficient for δ- and μ-opioid receptors exhibit opposing alterations of emotional responses

2000 • 653 citations

Cloning and functional comparison of kappa and delta opioid receptors from mouse brain.

1993 • 614 citations

Use of the elevated plus maze in the search for novel anxiolytic agents

1995 • 570 citations

The Relationship Between Pain and Depression

1996 • 479 citations

Cloning and pharmacological characterization of a rat μ opioid receptor

1993 • 460 citations

Cloning and pharmacological characterization of a rat kappa opioid receptor.

1993 • 422 citations

mu opiate receptor: cDNA cloning and expression.

1993 • 405 citations

Primary structures and expression from cDNAs of rat opioid receptor δ‐and μ‐subtypes

1993 • 277 citations

Prolonged Morphine Treatment Targets δ Opioid Receptors to Neuronal Plasma Membranes and Enhances δ-Mediated Antinociception

2001 • 232 citations

Decreased experimental anxiety and voluntary ethanol consumption in rats following central but not basolateral amygdala lesions

1997 • 229 citations

Clinical Aspects of Depression in Chronic Pain Patients

1991 • 220 citations

The alpha(2a)-adrenergic receptor plays a protective role in mouse behavioral models of depression and anxiety.

2001 • 218 citations

The Opiate Receptor

1974 • 188 citations

The α_2A-Adrenergic Receptor Plays a Protective Role in Mouse Behavioral Models of Depression and Anxiety

2001 • 187 citations

Nonpeptidic δ-opioid Receptor Agonists Reduce Immobility in the Forced Swim Assay in Rats

2002 • 172 citations

Direct evidence for the involvement of brain‐derived neurotrophic factor in the development of a neuropathic pain‐like state in mice

2005 • 170 citations

Suppression of the morphine‐induced rewarding effect in the rat with neuropathic pain: implication of the reduction in µ‐opioid receptor functions in the ventral tegmental area

2002 • 139 citations

A Lateralized Deficit in Morphine Antinociception after Unilateral Inactivation of the Central Amygdala

1998 • 137 citations

mCPP-induced anxiety in the light-dark box in rats - a new method for screening anxiolytic activity

1998 • 133 citations

Direct Evidence for the Involvement of the Mesolimbic κ-Opioid System in the Morphine-Induced Rewarding Effect Under an Inflammatory Pain-Like State

2004 • 123 citations

Effects of the non-competitive NMDA receptor antagonist ifenprodil on the morphine-induced place preference in mice

1999 • 111 citations

Cloning and pharmacological characterization of mouse TRPV1

2004 • 107 citations

Suppression of the morphine-induced rewarding effect and G-protein activation in the lower midbrain following nerve injury in the mouse: involvement of G-protein-coupled receptor kinase 2

2003 • 78 citations

Effects of mu-opioid receptor stimulation in the hypothalamic paraventricular nucleus on basal and stress-induced catecholamine secretion and cardiovascular responses.

1986 • 59 citations

Up-regulation of the TrkB receptor in mice injured by the partial ligation of the sciatic nerve

2000 • 54 citations

Behavioral changes induced by stressful situations: effects of enkephalins, dynorphin, and their interactions.

1990 • 49 citations

The reliability of depression diagnosis in chronic low back pain

1995 • 42 citations

The Opiate Receptors

1988 • 38 citations

Involvement of spinal protein kinase C in thermal hyperalgesia evoked by partial sciatic nerve ligation, but not by inflammation in the mouse

2000 • 36 citations

Involvement of μ-opioid receptors in the modulation of pituitary-adrenal axis in normal and stressed rats

1995 • 36 citations

Role of the κ-opioid system in the attenuation of the morphine-induced place preference under chronic pain

1998 • 31 citations