Cloning and pharmacological characterization of a rat kappa opioid receptor.

LIGAND: A versatile computerized approach for characterization of ligand-binding systems

1980 • 8,534 citations

High-efficiency transformation of mammalian cells by plasmid DNA.

1987 • 5,377 citations

Cloning of a Delta Opioid Receptor by Functional Expression

1992 • 1,225 citations

Autoradiographic differentiation of mu, delta and kappa opioid receptors in the rat forebrain and midbrain

1988 • 980 citations

Opposite effects of mu and kappa opiate agonists on dopamine release in the nucleus accumbens and in the dorsal caudate of freely moving rats.

1988 • 913 citations

Psychotomimesis Mediated by κ Opiate Receptors

1986 • 822 citations

Molecular cloning and characterization of an adenosine receptor: the A3 adenosine receptor.

1992 • 649 citations

Cloning and functional comparison of kappa and delta opioid receptors from mouse brain.

1993 • 614 citations

Localization of dopamine D2 receptor mRNA and D1 and D2 receptor binding in the rat brain and pituitary: an in situ hybridization- receptor autoradiographic analysis

1990 • 466 citations

Multiple opioid receptors: ligand selectivity profiles and binding site signatures.

1989 • 441 citations

Specific receptor for the opioid peptide dynorphin: structure--activity relationships.

1981 • 411 citations

ACTH: A SHORT INTRODUCTORY REVIEW*

1977 • 389 citations

Kappa opiate receptor multiplicity: evidence for two U50,488-sensitive kappa 1 subtypes and a novel kappa 3 subtype.

1989 • 331 citations

Amino-terminal leucine-rich repeats in gonadotropin receptors determine hormone selectivity.

1991 • 330 citations

Characterization and visualization of rat and guinea pig brain kappa opioid receptors: evidence for kappa 1 and kappa 2 opioid receptors.

1988 • 315 citations

Multiple opiate receptors: Support for unique mu, delta and kappa sites

1982 • 268 citations

Molecular mechanism of opioid receptor selection

1986 • 258 citations

Extracellular domain of lutropin/choriogonadotropin receptor expressed in transfected cells binds choriogonadotropin with high affinity.

1990 • 237 citations

Nonopiate Effects of Dynorphin and Des-Tyr-Dynorphin

1982 • 235 citations

Opiates inhibit adenylate cyclase by stimulating GTP hydrolysis.

1981 • 234 citations

Involvement of dynorphin and the kappa opioid receptor in feeding

1983 • 170 citations

Interaction of endogenous opioid peptides and other drugs with four kappa opioid binding sites in guinea pig brain

1990 • 148 citations

Molecular characterization of a new immunoglobulin superfamily protein with potential roles in opioid binding and cell contact.

1989 • 124 citations

K‐Opiate Agonists Inhibit Adenylate Cyclase and Produce Heterologous Desensitization in Rat Spinal Cord

1989 • 119 citations

Identification of a specific site required for rapid heterologous desensitization of the beta-adrenergic receptor by cAMP-dependent protein kinase.

1989 • 115 citations

Opioid receptors and endogenous opioid peptides

1991 • 107 citations

Diuresis and suppression of vasopressin by kappa opioids: comparison with mu and delta opioids and clonidine.

1985 • 86 citations

Kappa opiate agonists modulate the hypothalamic-pituitary-adrenocortical axis in the rat.

1986 • 71 citations

Identification of hormone-binding regions of the luteinizing hormone/human chorionic gonadotropin receptor using synthetic peptides.

1992 • 62 citations

Expression cloning of cDNA encoding a seven-helix receptor from human placenta with affinity for opioid ligands.

1992 • 48 citations

Receptor-mediated stimulation of brain GTPase by opiates in normal and dependent rats

1984 • 42 citations

Opioid Receptors and their Pharmacological Profiles

1992 • 38 citations

Recent Studies on Opioid Receptors: Heterogeneity and Purification

1986 • 30 citations

Relationship between kappa1 opioid receptor binding and inhibition of adenylyl cyclase in guinea pig brain membranes

1993 • 27 citations

Kappa-Opioid-Receptor-Mediated Regulation of α-Melanocyte-Stimulating Hormone Secretion and Tuberohypophysial Dopaminergic Neuronal Activity

1990 • 24 citations