Pre-existing T-cell immunity against mucin-1 in breast cancer patients and healthy volunteers

The human cytotoxic T-lymphocyte (CTL) response to cytomegalovirus is dominated by structural protein pp65: frequency, specificity, and T-cell receptor usage of pp65-specific CTL

1996 • 711 citations

Induction of cytotoxic T-lymphocyte responses in vivo after vaccinations with peptide-pulsed dendritic cells

2000 • 544 citations

Breast cancer genetics: What we know and what we need

2001 • 460 citations

Specific, major histocompatibility complex-unrestricted recognition of tumor-associated mucins by human cytotoxic T cells.

1989 • 453 citations

CD40-activated human B cells: an alternative source of highly efficient antigen presenting cells to generate autologous antigen-specific T cells for adoptive immunotherapy.

1997 • 365 citations

Immediate Early and Early Lytic Cycle Proteins Are Frequent Targets of the Epstein-Barr Virus–induced Cytotoxic T Cell Response

1997 • 362 citations

Identification of HLA-A2–Restricted T-Cell Epitopes Derived From the MUC1 Tumor Antigen for Broadly Applicable Vaccine Therapies

1999 • 301 citations

Antibody and T cell responses of patients with adenocarcinoma immunized with mannan-MUC1 fusion protein.

1997 • 269 citations

Therapy of human tumors in NOD/SCID mice with patient-derived reactivated memory T cells from bone marrow

2001 • 269 citations

A Phase I Trial of a Synthetic Mucin Peptide Vaccine

1996 • 268 citations

MUC‐1 Epithelial Tumor Mucin‐Based Immunity and Cancer Vaccines

1995 • 267 citations

Cytotoxic T cells from ovarian malignant tumors can recognize polymorphic epithelial mucin core peptides.

1993 • 213 citations

Vaccination of high-risk breast cancer patients with mucin-1 (MUC1) keyhole limpet hemocyanin conjugate plus QS-21.

2000 • 201 citations

Natural T cell immunity against cancer.

2003 • 197 citations

Pre-existent immunity to the HER-2/neu oncogenic protein in patients with HER-2/neu overexpressing breast and ovarian cancer

2000 • 161 citations

Mucin gene (MUC1) transfected dendritic cells as vaccine: results of a phase I/II clinical trial

2002 • 157 citations

Identification of tumor-associated MHC class I ligands by a novel T cell-independent approach

2000 • 134 citations

Real-Time Quantitative Polymerase Chain Reaction Assessment of Immune Reactivity in Melanoma Patients After Tumor Peptide Vaccination

2000 • 104 citations

Reevaluation of the cellular immune response in breast cancer patients vaccinated with MUC1

2001 • 76 citations

Phase I Trial of Antigen-Specific Gene Therapy Using a Recombinant Vaccinia Virus Encoding MUC-1 and IL-2 in MUC-1-Positive Patients With Advanced Prostate Cancer

2004 • 75 citations

In vitro induction of MUC-1 peptide-specific type 1 T lymphocyte and cytotoxic T lymphocyte responses from healthy multiparous donors.

1996 • 72 citations

Antibodies reactive with the protein core of MUC1 mucin are present in ovarian cancer patients and healthy women

1998 • 67 citations

Does pregnancy immunize against breast cancer?

1995 • 67 citations

Cytotoxic T lymphocytes derived from bone marrow mononuclear cells of multiple myeloma patients recognize an underglycosylated form of MUC1 mucin

1997 • 62 citations

Melan-A/MART-1-specific CD8 T cells: from thymus to tumor

2002 • 60 citations

Evaluation of pre-existent immunity in patients with primary breast cancer: molecular and cellular assays to quantify antigen-specific T lymphocytes in peripheral blood mononuclear cells.

2003 • 56 citations

MUC1 and breast cancer.

1999 • 52 citations

Monoclonal antibodies to epithelial sialomucins recognize epitopes at different cellular sites in adenolymphomas of the parotid gland

1988 • 39 citations

Differences in T‐cell immunity toward tumor‐associated antigens in colorectal cancer and breast cancer patients

2003 • 38 citations

Cellular and humoral immune responses to MUC1 mucin and tandem-repeat peptides in ovarian cancer patients and controls

1999 • 35 citations

Identification of type B-specific and cross-reactive cytotoxic T-lymphocyte responses to Epstein-Barr virus

1996 • 28 citations

Circulating tumour-associated mucin concentrations, determined by the CASA assay, in healthy women

1993 • 20 citations

Soluble HLA-A2.1 restricted peptides that are recognized by influenza virus specific cytotoxic T lymphocytes

1991 • 20 citations

Tumor-associated antigen profiling in breast and ovarian cancer: mRNA, protein or T cell recognition?

2003 • 14 citations

CD8+ T-cell response against MUC1-derived peptides in gastrointestinal cancer survivors

2004 • 13 citations