Interactions between progestins and heregulin (HRG) signaling pathways: HRG acts as mediator of progestins proliferative effects in mouse mammary adenocarcinomas

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

1949 • 19,979 citations

ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling

1997 • 1,554 citations

Identification of Heregulin, a Specific Activator of p185 ^erbB2

1992 • 963 citations

A neu acquaintance for ErbB3 and ErbB4: A role for receptor heterodimerization in growth signaling

1994 • 601 citations

Neu differentiation factor: A transmembrane glycoprotein containing an EGF domain and an immunoglobulin homology unit

1992 • 579 citations

Isolation of the NeuHER-2 stimulatory ligand: A 44 kd glycoprotein that induces differentiation of mammary tumor cells

1992 • 534 citations

Effect of a null mutation of the insulin-like growth factor I receptor gene on growth and transformation of mouse embryo fibroblasts.

1994 • 527 citations

Myc but not Fos rescue of PDGF signalling block caused by kinase-inactive Src

1995 • 309 citations

Sequential requirement of hepatocyte growth factor and neuregulin in the morphogenesis and differentiation of the mammary gland.

1995 • 304 citations

Single-Chain Antibody-Mediated Intracellular Retention of ErbB-2 Impairs Neu Differentiation Factor and Epidermal Growth Factor Signaling

1995 • 300 citations

Neu and its ligands: From an oncogene to neural factors

1993 • 286 citations

A functional insulin-like growth factor I receptor is required for the mitogenic and transforming activities of the epidermal growth factor receptor.

1994 • 282 citations

Efficient coupling with phosphatidylinositol 3-kinase, but not phospholipase C gamma or GTPase-activating protein, distinguishes ErbB-3 signaling from that of other ErbB/EGFR family members.

1994 • 231 citations

Neu Differentiation Factor Activation of ErbB-3 and ErbB-4 Is Cell Specific and Displays a Differential Requirement for ErbB-2

1995 • 187 citations

Effect of a Null Mutation of the Insulin-Like Growth Factor I Receptor Gene on Growth and Transformation of Mouse Embryo Fibroblasts

1994 • 162 citations

Association of IRS-1 with the insulin receptor and the phosphatidylinositol 3'-kinase. Formation of binary and ternary signaling complexes in intact cells.

1993 • 160 citations

Structural and functional aspects of the multiplicity of Neu differentiation factors.

1994 • 148 citations

Signal transduction pathways activated and required for mammary carcinogenesis in response to specific oncogenes

1998 • 130 citations

Involvement of heregulin-beta2 in the acquisition of the hormone-independent phenotype of breast cancer cells.

1996 • 120 citations

ErbB receptors and EGF-like ligands: cell lineage determination and oncogenesis through combinatorial signaling.

1997 • 117 citations

Neu differentiation factor/heregulin modulates growth and differentiation of HC11 mammary epithelial cells.

1995 • 98 citations

erbB-2 antisense oligonucleotides inhibit the proliferation of breast carcinoma cells with erbB-2 oncogene amplification

1994 • 97 citations

Expression of messenger RNA for amphiregulin, heregulin, and cripto-1, three new members of the epidermal growth factor family, in human breast carcinomas

1995 • 83 citations

Bidirectional interactions between the estrogen receptor and the c‐erbB‐2 signaling pathways: Heregulin inhibits estrogenic effects in breast cancer cells

1995 • 72 citations

A Functional Insulin-Like Growth Factor I Receptor Is Required for the Mitogenic and Transforming Activities of the Epidermal Growth Factor Receptor

1994 • 69 citations

Characterization of a breast cancer cell differentiation factor that specifically activates the HER4/p180erbB4 receptor.

1993 • 68 citations

Mitogenic activity of neu differentiation factor/heregulin mimics that of epidermal growth factor and insulin‐like growth factor‐I in human mammary epithelial cells

1995 • 65 citations

EXPRESSION OF AMPHIREGULIN, CRIPTO-1, AND HEREGULIN-ALPHA IN HUMAN BREAST-CANCER CELLS

1993 • 63 citations

The role of erbB2 signal transduction pathways in human breast cancer

1993 • 58 citations

Varying patterns of expression of insulin-like growth factors I and II and their receptors in murine mammary adenocarcinomas of different metastasizing ability

1996 • 49 citations

Mammary adenocarcinomas induced by medroxyprogesterone acetate: Hormone dependence and egf receptors of BALB/c In vivo sublines

1989 • 46 citations

Effect of medroxyprogesterone acetate (MPA) and serum factors on cell proliferation in primary cultures of an MPA-induced mammary adenocarcinoma

1995 • 42 citations

A processed pseudogene in an intron of the HLA-DPβ1 chain gene is a member of the ribosomal protein L32 gene family

1985 • 37 citations

Regulation of estrogen receptor concentration and activity by an erbB/HER ligand in breast carcinoma cell lines.

1996 • 37 citations

Growth Factor-Induced Transcription via the Serum Response Element Is Inhibited by Cyclic Adenosine 3′,5′-Monophosphate in MCF-7 Breast Cancer Cells*

1997 • 23 citations

Involvement of insulin-like growth factors-I and -II and their receptors in medroxyprogesterone acetate-induced growth of mouse mammary adenocarcinomas

1998 • 21 citations

Efficient coupling with phosphatidylinositol 3-kinase, but not phospholipase Cϒ or GTPase-activating protein, distinguishes ErbB-3 signaling from that of other ErbB/EGFR family members

1994 • 20 citations

Colonization pattern of aquatic hyphomycetes on leaf packs in subtropical stream.

1997 • 17 citations

Changes in heregulin β1 (HRGβ1) signaling after inhibition of ErbB-2 expression in a human breast cancer cell line

1998 • 7 citations