Adult‐born hippocampal neurons promote cognitive flexibility in mice

Requirement of Hippocampal Neurogenesis for the Behavioral Effects of Antidepressants

2003 • 4,175 citations

More hippocampal neurons in adult mice living in an enriched environment

1997 • 3,476 citations

Functional neurogenesis in the adult hippocampus

2002 • 2,813 citations

Simple memory: a theory for archicortex

1971 • 2,722 citations

New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory?

2010 • 2,004 citations

A Functional Role for Adult Hippocampal Neurogenesis in Spatial Pattern Separation

2009 • 1,563 citations

Increasing adult hippocampal neurogenesis is sufficient to improve pattern separation

2011 • 1,458 citations

Adult hippocampal neurogenesis buffers stress responses and depressive behaviour

2011 • 1,360 citations

For the Long Run

2004 • 1,289 citations

Enhanced synaptic plasticity in newly generated granule cells of the adult hippocampus

2004 • 1,256 citations

Environment-specific expression of the immediate-early gene Arc in hippocampal neuronal ensembles

1999 • 1,024 citations

Roles of continuous neurogenesis in the structural and functional integrity of the adult forebrain

2008 • 1,011 citations

Inhibition of Activity-Dependent Arc Protein Expression in the Rat Hippocampus Impairs the Maintenance of Long-Term Potentiation and the Consolidation of Long-Term Memory

2000 • 1,007 citations

Ablation of hippocampal neurogenesis impairs contextual fear conditioning and synaptic plasticity in the dentate gyrus

2006 • 992 citations

GFAP-expressing progenitors are the principal source of constitutive neurogenesis in adult mouse forebrain

2004 • 963 citations

A Critical Period for Enhanced Synaptic Plasticity in Newly Generated Neurons of the Adult Brain

2007 • 886 citations

Neurogenesis may relate to some but not all types of hippocampal‐dependent learning

2002 • 854 citations

Preferential incorporation of adult-generated granule cells into spatial memory networks in the dentate gyrus

2007 • 854 citations

Storage of Spatial Information by the Maintenance Mechanism of LTP

2006 • 840 citations

A role for adult neurogenesis in spatial long-term memory

2004 • 830 citations

Arc/Arg3.1 Is Essential for the Consolidation of Synaptic Plasticity and Memories

2006 • 810 citations

Synaptic Activation Causes the mRNA for the IEG Arc to Localize Selectively near Activated Postsynaptic Sites on Dendrites

1998 • 807 citations

Spatial selectivity of unit activity in the hippocampal granular layer

1993 • 764 citations

Neurons born in the adult dentate gyrus form functional synapses with target cells

2008 • 709 citations

Experience-Dependent Gene Expression in the Rat Hippocampus after Spatial Learning: A Comparison of the Immediate-Early GenesArc, c-fos, andzif268

2001 • 680 citations

Resolving New Memories: A Critical Look at the Dentate Gyrus, Adult Neurogenesis, and Pattern Separation

2011 • 633 citations

Potential role for adult neurogenesis in the encoding of time in new memories

2006 • 631 citations

Inhibition of neurogenesis interferes with hippocampus‐dependent memory function

2006 • 573 citations

Adult-Generated Hippocampal Neurons Allow the Flexible Use of Spatially Precise Learning Strategies

2009 • 570 citations

Spatial Relational Memory Requires Hippocampal Adult Neurogenesis

2008 • 568 citations

A role for adult TLX-positive neural stem cells in learning and behaviour

2008 • 512 citations

Experience-Specific Functional Modification of the Dentate Gyrus through Adult Neurogenesis: A Critical Period during an Immature Stage

2007 • 505 citations

Pattern Separation: A Common Function for New Neurons in Hippocampus and Olfactory Bulb

2011 • 497 citations

Forebrain-Specific Calcineurin Knockout Selectively Impairs Bidirectional Synaptic Plasticity and Working/Episodic-like Memory

2001 • 489 citations

Arrested neuronal proliferation and impaired hippocampal function following fractionated brain irradiation in the adult rat

2003 • 476 citations

Adult-Born Hippocampal Dentate Granule Cells Undergoing Maturation Modulate Learning and Memory in the Brain

2009 • 467 citations

Adult Neurogenesis Modulates the Hippocampus-Dependent Period of Associative Fear Memory

2009 • 463 citations

Hippocampal neurogenesis is not required for behavioral effects of environmental enrichment

2006 • 449 citations

The neurogenic reserve hypothesis: what is adult hippocampal neurogenesis good for?

2008 • 368 citations

Sparse, environmentally selective expression ofArc RNA in the upper blade of the rodent fascia dentata by brief spatial experience

2005 • 367 citations

Endogenous anxiety and stress responses in water maze and Barnes maze spatial memory tasks

2008 • 360 citations

Induction and Experience-Dependent Consolidation of Stable Long-Term Potentiation Lasting Months in the Hippocampus

2002 • 342 citations

Adult‐born hippocampal neurons mature into activity‐dependent responsiveness

2003 • 322 citations

Integration of New Neurons into Functional Neural Networks

2006 • 320 citations

A functional hypothesis for adult hippocampal neurogenesis: Avoidance of catastrophic interference in the dentate gyrus

2006 • 290 citations

What is the mammalian dentate gyrus good for?

2008 • 271 citations

PKMζ Maintains Spatial, Instrumental, and Classically Conditioned Long-Term Memories

2008 • 258 citations

Reliable Activation of Immature Neurons in the Adult Hippocampus

2009 • 258 citations

A computational principle for hippocampal learning and neurogenesis

2005 • 245 citations

Intact neurogenesis is required for benefits of exercise on spatial memory but not motor performance or contextual fear conditioning in C57BL/6J mice

2008 • 227 citations

The Activity-Regulated Cytoskeletal-Associated Protein (Arc/Arg3.1) Is Required for Memory Consolidation of Pavlovian Fear Conditioning in the Lateral Amygdala

2008 • 201 citations

Dynamic Grouping of Hippocampal Neural Activity During Cognitive Control of Two Spatial Frames

2010 • 192 citations

4‐ to 6‐week‐old adult‐born hippocampal neurons influence novelty‐evoked exploration and contextual fear conditioning

2011 • 190 citations

Stress, Glucocorticoids, and Memory: A Meta-analytic Review

2003 • 187 citations

Recruitment of adult-generated neurons into functional hippocampal networks contributes to updating and strengthening of spatial memory

2009 • 187 citations

Effects of adult‐generated granule cells on coordinated network activity in the dentate gyrus

2010 • 178 citations

Hippocampectomy and response perseveration in the rat.

1965 • 177 citations

Suppression of adult neurogenesis leads to an increased hypothalamo-pituitary-adrenal axis response

2009 • 172 citations

Attention-Like Modulation of Hippocampus Place Cell Discharge

2010 • 171 citations

An Animal Model of a Behavioral Intervention for Depression

2008 • 160 citations

Arrest of adult hippocampal neurogenesis in mice impairs single- but not multiple-trial contextual fear conditioning.

2010 • 158 citations

A Critical Role for α4βδ GABA _A Receptors in Shaping Learning Deficits at Puberty in Mice

2010 • 155 citations

Inactivating one hippocampus impairs avoidance of a stable room-defined place during dissociation of arena cues from room cues by rotation of the arena

2001 • 153 citations

The effects of running and of inhibiting adult neurogenesis on learning and memory in rats

2008 • 153 citations

Beyond Memory, Navigation, and Inhibition: Behavioral Evidence for Hippocampus-Dependent Cognitive Coordination in the Rat

2005 • 152 citations

Effect of ablated hippocampal neurogenesis on the formation and extinction of contextual fear memory

2009 • 143 citations

Inhibition of adult hippocampal neurogenesis disrupts contextual learning but spares spatial working memory, long-term conditional rule retention and spatial reversal

2008 • 132 citations

Both here and there: Simultaneous expression of autonomous spatial memories in rats

1998 • 111 citations

Place navigation in rats with unilateral tetrodotoxin inactivation of the dorsal hippocampus: Place but not procedural learning can be lateralized to one hippocampus.

1993 • 86 citations

Place navigation in rats with unilateral tetrodotoxin inactivation of the dorsal hippocampus: Place but not procedural learning can be lateralized to one hippocampus.

1993 • 79 citations

Adult hippocampal neurogenesis and memory interference

2011 • 76 citations

Electroconvulsive seizure restores neurogenesis and hippocampus‐dependent fear memory after disruption by irradiation

2008 • 70 citations

Behavioral Evidence That Segregation and Representation Are Dissociable Hippocampal Functions

2005 • 67 citations

Parameters Relevant to the Experimental Production of “Stress” in the Mouse

1965 • 27 citations

What Do Place Cells Tell Us about Learning to Associate and Learning to Segregate?

2008 • 6 citations