The Linear-Quadratic Model Is an Appropriate Methodology for Determining Isoeffective Doses at Large Doses Per Fraction
Data up to Jan 2025
Total Citations Per Year
Abstract
References (56)
The linear-quadratic formula and progress in fractionated radiotherapy
1989 • 2,150 citations
Tumor Response to Radiotherapy Regulated by Endothelial Cell Apoptosis
2003 • 1,538 citations
Dose fractionation, dose rate and iso-effect relationships for normal tissue responses
1982 • 1,081 citations
Fractionation and protraction for radiotherapy of prostate carcinoma
1999 • 931 citations
The application of the linear-quadratic dose-effect equation to fractionated and protracted radiotherapy
1985 • 826 citations
The theory of dual radiation action
1974 • 638 citations
The Effect of Multiple Small Doses of X Rays on Skin Reactions in the Mouse and a Basic Interpretation
1976 • 596 citations
[Fractionation in radiotherapy].
1972 • 487 citations
An ‘Incomplete-repair’ Model for Survival after Fractionated and Continuous Irradiations
1985 • 471 citations
Lethal and Potentially Lethal Lesions Induced by Radiation --- A Unified Repair Model
1986 • 469 citations
An Introduction to Mathematics.
1913 • 453 citations
The mechanism of the induction by radiation of chromosome aberrations inTradescantia
1942 • 402 citations
What hypofractionated protocols should be tested for prostate cancer?
2003 • 304 citations
The Interpretation of Microbial Inactivation and Recovery Phenomena
1966 • 232 citations
Review The link between low-LET dose-response relations and the underlying kinetics of damage production/repair/misrepair
1997 • 230 citations
A microdosimetric-kinetic model of cell death from exposure to ionizing radiation of any LET, with experimental and clinical applications
1996 • 211 citations
THEORY OF DUAL RADIATION ACTION.
1972 • 208 citations
The Linear-Quadratic Model and Most Other Common Radiobiological Models Result in Similar Predictions of Time-Dose Relationships
1998 • 206 citations
The Repair-Misrepair Model in Radiobiology: Comparison to Other Models
1985 • 163 citations
Isoeffect models and fractionated radiation therapy
1987 • 154 citations
An Introduction to Mathematics.
1959 • 136 citations
Fractionated regimens for stereotactic radiotherapy of recurrent tumors in the brain
1991 • 122 citations
A convenient extension of the linear-quadratic model to include redistribution and reoxygenation
1995 • 116 citations
The Relationship of DNA and Chromosome Damage to Survival of Synchronized X-Irradiated L5178Y Cells: II. Repair
1988 • 103 citations
Hypofractionation for Prostate Cancer: A Critical Review
2008 • 98 citations
Fitting the linear–quadratic model to detailed data sets for different dose ranges
2006 • 86 citations
Fractionation in Radiotherapy
1987 • 83 citations
A brief survey of aberration origin theories
1998 • 82 citations
Tests for the fit of the linear-quadratic model to radiation isoeffect data
1984 • 77 citations
Fractionated high dose-rate versus low dose-rate regimens for intracavitary brachytherapy of the cervix: Equivalent regimens for combined brachytherapy and external irradiation
1991 • 68 citations
Introduction to Mathematics
1970 • 66 citations
The Repair-Misrepair Model in Radiobiology: Comparison to Other Models
1985 • 60 citations
Biophysical modelling of radiation effects
1992 • 58 citations
Dangers of the clinical use of the NSD formula for small fraction numbers
1975 • 58 citations
Multivariate determinants of radiocurability I: Prediction of single fraction tumor control doses
1994 • 50 citations
The mechanistic basis of the linear‐quadratic formalism
1998 • 48 citations
Repair processes and cell survival
1972 • 45 citations
An equation for the dose response of radiation-induced apoptosis: possible incorporation with the LQ model
1994 • 41 citations
Quantitative Mathematical Models in Radiation Biology
1988 • 36 citations
Chronic Effects of Neutrons and Charged Particles on Spinal Cord, Lung, and Rectum
1985 • 34 citations
An Examination of the Repair Saturation Hypothesis for Describing Shouldered Survival Curves
1991 • 31 citations
Quantitative mathematical models in radiation biology
1988 • 27 citations
Cell cycle and growth response of CHO cells to X-irradiation: Threshold-free repair at low doses
2001 • 25 citations
The saturated repair kinetics of Chinese hamster V79 cells suggests a damage accumulation--interaction model of cell killing.
1990 • 23 citations
Four-dimensional Stereotactic Radiotherapy for Early Stage Non-Small Cell Lung Cancer: A Comparative Planning Study
2008 • 23 citations
The Poor Statistical Properties of the Fe-plot
1989 • 21 citations
The use of the D versus dD plot to estimate the ratio from iso-effect radiation damage data
1988 • 21 citations
Is NSD-TDF useful to radiotherapy?
1985 • 20 citations
A cell survival model with saturable repair after irradiation
1987 • 20 citations
Mechanical Assay of Consequential and Primary Late Radiation Effects in Murine Small Intestine: Alpha/Beta Analysis
1994 • 18 citations
The Saturated Repair Kinetics of Chinese Hamster V79 Cells Suggests a Damage Accumulation-Interaction Model of Cell Killing
1990 • 16 citations
Mechanisms of Induction of Specific Chromosomal Alterations
1990 • 13 citations
The biological basis of fractionation.
2004 • 12 citations
Model of mammalian cell reproductive death I. Basic assumptions and general equations
1993 • 9 citations
Chronic Effects of Neutrons and Charged Particles on Spinal Cord, Lung, and Rectum
1985 • 8 citations
Skin reaction as a biological parameter for prospective studies of different dose schedules with the CRE formula.
1976 • 4 citations