Mechanisms of Induction of Specific Chromosomal Alterations

The double-strand-break repair model for recombination

1983 • 2,468 citations

The repair of double-strand breaks in DNA: A model involving recombination

1976 • 499 citations

Preferential DNA repair of an active gene in human cells.

1986 • 455 citations

Enzymatic Restriction of Mammalian Cell DNA Using Pvu II and Bam H1: Evidence for the Double-strand Break Origin of Chromosomal Aberrations

1984 • 313 citations

Molecular mechanisms involved in the production of chromosomal aberrations

1984 • 303 citations

Characterization of Giemsa dark- and light-band DNA

1982 • 251 citations

Human telomeres: fusion and interstitial sites

1989 • 248 citations

Hypervariable minisatellite DNA is a hotspot for homologous recombination in human cells

1990 • 226 citations

Survival of UV-irradiated mammalian cells correlates with efficient DNA repair in an essential gene.

1986 • 196 citations

The effect of cytosine arabinoside on the frequency of single-strand breaks in DNA of mammalian cells following irradiation or chemical treatment

1977 • 163 citations

The effect of cytosine arabinoside on the frequency of X-ray-induced chromosome aberrations in normal human leukocytes

1980 • 138 citations

Use of Restriction Endonucleases to Study Relationships between DNA Double-strand Breaks, Chromosomal Aberrations and Other End-points in Mammalian Cells

1988 • 112 citations

Assignment of aberration breakpoints in banded chromosomes

1977 • 76 citations

Chromosomal aberrations induced by restriction endonucleases

1985 • 63 citations

The induction of chromosome aberrations by restriction endonucleases that produce blunt-end or cohesive-end double-strand breaks

1988 • 61 citations

Sister-chromatid exchanges and gene mutations are induced by the replication of 5-bromo- and 5-chloro-deoxyuridine substituted DNA

1983 • 58 citations

SCE induction is proportional to substitution in DNA for thymidine by CldU and BrdU

1983 • 47 citations

The induction of chromosome-type aberrations in G1 by methyl methanesulfonate and 4-nitroquinoline-N-oxide, and the non-requirement of an S-phase for their production

1981 • 41 citations

Inducible Expression and Cytogenetic Effects of the EcoRI Restriction Endonuclease in Chinese Hamster Ovary Cells

1988 • 36 citations

Genetic hypervariability of telomere-related sequences is associated with meiosis inPlasmodium falciparum

1988 • 34 citations

TATA box-dependent protein-DNA interactions are detected on heat shock and histone gene promoters in nuclear extracts derived from Drosophila melanogaster embryos.

1988 • 32 citations

The effect of 3-aminobenzamide on the frequency of X-ray- or neutron-induced chromosome aberrations in cycling or non-cycling human lymphocytes

1985 • 30 citations

Radiation-induced Thymine Base Damage and Its Excision Repair in Active and Inactive Chromatin of HeLa Cells

1985 • 28 citations

DNA lesions, chromosomal aberrations and G2 delay in CHO cells cultured in medium containing bromo- or chloro-deoxyuridine

1984 • 26 citations

An explanation of interspecific differences in sensitivity to X-ray-induced chromosome aberrations and a consideration of dose-response curves

1985 • 12 citations

A comparative study of the relative frequency and specific pattern of chromatid interchanges induced by mono-, di- and poly-functional alkylating agents

1982 • 3 citations