Antigen from the Anterior Chamber of the Eye Travels in a Soluble Form to Secondary Lymphoid Organs via Lymphatic and Vascular Routes

Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo

1994 • 967 citations

Dynamics and Function of Langerhans Cells In Vivo

2005 • 899 citations

Ocular immune privilege: therapeutic opportunities from an experiment of nature

2003 • 744 citations

The Conduit System Transports Soluble Antigens from the Afferent Lymph to Resident Dendritic Cells in the T Cell Area of the Lymph Node

2005 • 714 citations

Lymph-Borne Chemokines and Other Low Molecular Weight Molecules Reach High Endothelial Venules via Specialized Conduits While a Functional Barrier Limits Access to the Lymphocyte Microenvironments in Lymph Node Cortex

2000 • 562 citations

Cells in the Marginal Zone of the Spleen

1992 • 411 citations

Patterns of lymphatic drainage in the adult laboratory rat.

1971 • 397 citations

The macrophage F4/80 receptor is required for the induction of antigen-specific efferent regulatory T cells in peripheral tolerance

2005 • 354 citations

Induction of anterior chamber-associated immune deviation requires an intact, functional spleen.

1981 • 255 citations

Draining Lymph Nodes of Corneal Transplant Hosts Exhibit Evidence for Donor Major Histocompatibility Complex (MHC) Class II–positive Dendritic Cells Derived from MHC Class II–negative Grafts

2002 • 210 citations

A Conduit System Distributes Chemokines and Small Blood-borne Molecules through the Splenic White Pulp

2003 • 204 citations

Marginal zone macrophages identified by a monoclonal antibody: characterization of immuno- and enzyme-histochemical properties and functional capacities.

1985 • 179 citations

Studies on the induction of anterior chamber-associated immune deviation (ACAID). II. Eye-derived cells participate in generating blood-borne signals that induce ACAID.

1991 • 144 citations

Peptide-specific T cell clonal expansion in vivo following immunization in the eye, an immune-privileged site.

1996 • 106 citations

Basic physiology of the drainage of aqueous humor

1977 • 103 citations

Distinctive humoral immune responses following anterior chamber and intravenous administration of soluble antigen. Evidence for active suppression of IgG2-secreting B lymphocytes.

1990 • 97 citations

Macrophages capable of inducing anterior chamber associated immune deviation demonstrate spleen-seeking migratory properties.

1992 • 87 citations

Analysis of an in vitro-generated signal that induces systemic immune deviation similar to that elicited by antigen injected into the anterior chamber of the eye

1992 • 77 citations

Transplantation immunology of the anterior chamber of the eye. II. Immune response to allogeneic cells.

1975 • 74 citations

Do immunologically privileged sites require a functioning spleen?

1974 • 65 citations

The Distribution of Antigen in Lymphoid Tissues following Its Injection into the Anterior Chamber of the Rat Eye

2004 • 58 citations

Apoptosis, tolerance, and regulatory T cells – old wine, new wineskins

2003 • 58 citations

Intracamerally induced concomitant immunity: mice harboring progressively growing intraocular tumors are immune to spontaneous metastases and secondary tumor challenge.

1983 • 46 citations

APCs in the Anterior Uveal Tract Do Not Migrate to Draining Lymph Nodes

2004 • 44 citations

Tissue barriers, immunosuppressive microenvironments, and privileged sites: the eye's point of view.

1993 • 39 citations

Intraocular Tumor Antigen Drains Specifically to Submandibular Lymph Nodes, Resulting in an Abortive Cytotoxic T Cell Reaction

2004 • 38 citations

Injection of Soluble Antigen into the Anterior Chamber of the Eye Induces Expansion and Functional Unresponsiveness of Antigen-Specific CD8+ T Cells

2002 • 38 citations

The differing patterns of antigen release and local retention following anterior chamber and intravenous inoculation of soluble antigen. Evidence that the eye acts as an antigen depot.

1989 • 36 citations

Contribution of lymphatic drainage system in corneal allograft rejection in mice

2001 • 34 citations

Immunohistology of Antigen-Presenting Cells In Vivo: A Novel Method for Serial Observation of Fluorescently Labeled Cells

2003 • 33 citations

Local Retention of Soluble Antigen by Potential Antigen-Presenting Cells in the Anterior Segment of the Eye

2003 • 23 citations

An intravital and confocal microscopic study of the distribution of intracameral antigen in the aqueous outflow pathways and limbus of the rat eye

2004 • 20 citations

Localized gut-associated lymphoid tissue hemorrhage induced by intravenous peptidoglycan-polysaccharide polymers

1986 • 13 citations

Reconsidering the immunologic privilege and lymphatic drainage of the anterior chamber of the eye.

1989 • 7 citations