A Simple Molecular Complex Mediates Widespread BMP-Induced Repression during Drosophila Development

Identification and Functional Characterization of Distinct Critically Important Bone Morphogenetic Protein-specific Response Elements in the Id1 Promoter

2002 • 849 citations

Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways

2000 • 832 citations

A Niche Maintaining Germ Line Stem Cells in the Drosophila Ovary

2000 • 760 citations

Crystal Structure of a Smad MH1 Domain Bound to DNA

1998 • 709 citations

decapentaplegic Is Essential for the Maintenance and Division of Germline Stem Cells in the Drosophila Ovary

1998 • 648 citations

Neural induction, the default model and embryonic stem cells

2002 • 619 citations

A Self-Enabling TGFβ Response Coupled to Stress Signaling

2003 • 539 citations

THE SPECIFICATION OF DORSAL CELL FATES IN THE VERTEBRATE CENTRAL NERVOUS SYSTEM

1999 • 536 citations

Drosophila Mad binds to DNA and directly mediates activation of vestigial by Decapentaplegic

1997 • 524 citations

E2F4/5 and p107 as Smad Cofactors Linking the TGFβ Receptor to c-myc Repression

2002 • 475 citations

Three habits of highly effective signaling pathways: principles of transcriptional control by developmental cell signaling

2002 • 461 citations

A discrete transcriptional silencer in thebamgene determines asymmetric division of theDrosophilagermline stem cell

2003 • 438 citations

Dpp Signaling Silences bam Transcription Directly to Establish Asymmetric Divisions of Germline Stem Cells

2003 • 408 citations

Bmp signals from niche cells directly repress transcription of a differentiation-promoting gene,bag of marbles, in germline stem cells in theDrosophilaovary

2004 • 393 citations

Genome-wide analysis of clustered Dorsal binding sites identifies putative target genes in the Drosophila embryo

2001 • 378 citations

TGF-β Family Signal Transduction in Drosophila Development: From Mad to Smads

1999 • 324 citations

Transcriptional repression: the long and the short of it

2001 • 301 citations

Direct Binding of Smad1 and Smad4 to Two Distinct Motifs Mediates Bone Morphogenetic Protein-specific Transcriptional Activation ofId1 Gene

2002 • 279 citations

The Drosophila Gene brinker Reveals a Novel Mechanism of Dpp Target Gene Regulation

1999 • 262 citations

Smad proteins act in combination with synergistic and antagonistic regulators to target Dpp responses to theDrosophila mesoderm

1998 • 250 citations

brinker is a target of Dpp in Drosophila that negatively regulates Dpp-dependent genes

1999 • 232 citations

The drosophila schnurri gene acts in the Dpp/TGFβ signaling pathway and encodes a transcription factor homologous to the human MBP family

1995 • 212 citations

1998 warkany lecture: Signaling pathways in development

1999 • 209 citations

schnurri is required for drosophila Dpp signaling and encodes a zinc finger protein similar to the mammalian transcription factor PRDII-BF1

1995 • 200 citations

Dorsal Gradient Networks in the Drosophila Embryo

2002 • 193 citations

Conversion of an Extracellular Dpp/BMP Morphogen Gradient into an Inverse Transcriptional Gradient

2003 • 181 citations

A molecular mechanism for combinatorial control in yeast: MCM1 protein sets the spacing and orientation of the homeodomains of an α2 dimer

1992 • 170 citations

Integration of epithelial patterning and morphogenesis inDrosophila ovarian follicle cells

2000 • 169 citations

Transcriptional regulation of BMP4 synexpression in transgenic Xenopus

2004 • 160 citations

A Drosophila protein related to the human zinc finger transcription factor PRDII/MBPI/HIV-EP1 is required for dpp signaling

1995 • 125 citations

Schnurri mediates Dpp-dependent repression of brinker transcription

2000 • 119 citations

NEW EMBO MEMBER'S REVIEW: Nuclear interpretation of Dpp signaling in Drosophila

2001 • 114 citations

Smad-Dependent Recruitment of a Histone Deacetylase/Sin3A Complex Modulates the Bone Morphogenetic Protein-Dependent Transcriptional Repressor Activity of Nkx3.2

2003 • 107 citations

Compatibility between enhancers and promoters determines the transcriptional specificity of gooseberry and gooseberry neuro in the Drosophila embryo.

1994 • 105 citations

Drosophila bunched integrates opposing DPP and EGF signals to set the operculum boundary

2000 • 83 citations

Repression of Dpp Targets by Binding of Brinker to Mad Sites

2001 • 76 citations

Anti-Neural-Inhibition: A Conserved Mechanism for Neural Induction

1997 • 68 citations

Dissection of an indirect autoregulatory response of a homeotic Drosophila gene.

1993 • 66 citations

Role of the gooseberry gene in Drosophila embryos: maintenance of wingless expression by a wingless--gooseberry autoregulatory loop.

1993 • 63 citations

Gradients and thresholds: BMP response gradients unveiled in Drosophila embryos

2003 • 56 citations

A HOX complex, a repressor element and a 50 bp sequence confer regional specificity to a DPP-responsive enhancer

2001 • 48 citations

Combinatorial Activity of Pair-Rule Proteins on the Drosophila gooseberry Early Enhancer

2000 • 16 citations

Dissection of the Drosophila pourquoi-pas? promoter: Complex ovarian expression is driven by distinct follicle cell- and germ line-specific enhancers

1994 • 13 citations

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