Prediction of venous metastases, recurrence, and prognosis in hepatocellular carcinoma based on a unique immune response signature of the liver microenvironment

The Hallmarks of Cancer

2000 • 27,569 citations

Inflammation and cancer

2002 • 14,174 citations

A Gene-Expression Signature as a Predictor of Survival in Breast Cancer

2002 • 6,428 citations

Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes

2002 • 5,109 citations

Tumour-educated macrophages promote tumour progression and metastasis

2004 • 3,259 citations

Diagnosis of multiple cancer types by shrunken centroids of gene expression

2002 • 2,932 citations

A molecular signature of metastasis in primary solid tumors

2002 • 2,424 citations

Friends or foes — bipolar effects of the tumour stroma in cancer

2004 • 1,742 citations

Radical causes of cancer

2003 • 1,611 citations

Molecular pathogenesis of human hepatocellular carcinoma

2002 • 1,424 citations

Prediction of Survival in Follicular Lymphoma Based on Molecular Features of Tumor-Infiltrating Immune Cells

2004 • 1,395 citations

Classification and prediction of survival in hepatocellular carcinoma by gene expression profiling

2004 • 874 citations

Predicting hepatitis B virus–positive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning

2003 • 837 citations

Metastasis genes: A progression puzzle

2002 • 793 citations

CSF-1 regulation of the wandering macrophage: complexity in action

2004 • 732 citations

Oligonucleotide microarray for prediction of early intrahepatic recurrence of hepatocellular carcinoma after curative resection

2003 • 516 citations

Cytokines in cancer immunity and immunotherapy

2004 • 398 citations

Hepatocellular Carcinoma-Cause, Treatment and Metastasis

2001 • 379 citations

Nitric oxide-induced cellular stress and p53 activation in chronic inflammation

2002 • 346 citations

Growth and spread of hepatocellular carcinoma: A review of 240 consecutive autopsy cases

1990 • 331 citations

p53 and vascular endothelial growth factor regulate tumor growth of NOS2-expressing human carcinoma cells

1998 • 279 citations

Modulation of the Organ Microenvironment for Treatment of Cancer Metastasis

1995 • 244 citations

NK T Cells Contribute to Expansion of CD8⁺T Cells and Amplification of Antiviral Immune Responses to Respiratory Syncytial Virus

2002 • 172 citations

Mechanisms of Disease: inflammatory mediators and cancer prevention

2005 • 152 citations

Cancer-associated molecular signature in the tissue samples of patients with cirrhosis

2004 • 138 citations

Cytokine-stimulated nitric oxide production inhibits adenylyl cyclase and cAMP-dependent secretion in cholangiocytes

2003 • 130 citations

Natural killer cells: Primary target for hepatitis C virus immune evasion strategies?

2006 • 102 citations

Metastatic transcriptional pattern revealed by gene expression profiling in primary colorectal carcinoma

2005 • 100 citations

Host genetics and tumour metastasis

2004 • 91 citations

NK cell regulation of T cell-mediated responses

2004 • 88 citations

The interplay between innate and adaptive immunity regulates cancer development

2005 • 84 citations

Management of hepatocellular carcinoma.

2000 • 73 citations

Possible contribution of circulating interleukin-10 (IL-10) to anti-tumor immunity and prognosis in patients with unresectable hepatocellular carcinoma

2003 • 53 citations

Germ Line Polymorphism in Metastatic Progression

2006 • 52 citations

Mechanisms of cancer invasion and metastasis.

1985 • 45 citations

Interferon (IFN)-gamma and Herpes simplex virus/tumor necrosis factor-alpha synergistically induce nitric oxide synthase 2 in macrophages through cooperative action of nuclear factor-kappa B and IFN regulatory factor-1.

2001 • 41 citations

NKT cells and viral immunity

2004 • 34 citations

NK Cells in Autoimmune Disease

2005 • 31 citations

Peripheral Blood Immunological Parameters for Use as Markers of Pre-invasive to Invasive Colorectal Cancer

2002 • 28 citations