The HEAT repeat protein Blm10 regulates the yeast proteasome by capping the core particle

Designer deletion strains derived fromSaccharomyces cerevisiae S288C: A useful set of strains and plasmids for PCR-mediated gene disruption and other applications

1998 • 3,373 citations

Structure of 20S proteasome from yeast at 2.4Å resolution

1997 • 2,211 citations

SPIDER and WEB: Processing and Visualization of Images in 3D Electron Microscopy and Related Fields

1996 • 2,073 citations

Three new dominant drug resistance cassettes for gene disruption inSaccharomyces cerevisiae

1999 • 1,793 citations

Epitope tagging of yeast genes using a PCR-based strategy: more tags and improved practical routines

1999 • 1,080 citations

A gated channel into the proteasome core particle.

2000 • 791 citations

Proteasomes and their kin: proteases in the machine age

2004 • 727 citations

A cryptic protease couples deubiquitination and degradation by the proteasome

2002 • 720 citations

Negative staining and image classification — powerful tools in modern electron microscopy

2004 • 674 citations

Multiple Associated Proteins Regulate Proteasome Structure and Function

2002 • 633 citations

Protein Repeats: Structures, Functions, and Evolution

2001 • 607 citations

Comparison of ARM and HEAT protein repeats

2001 • 511 citations

Structural basis for the activation of 20S proteasomes by 11S regulators

2000 • 503 citations

The Regulatory Particle of the Saccharomyces cerevisiae Proteasome

1998 • 487 citations

The base of the proteasome regulatory particle exhibits chaperone-like activity

1999 • 485 citations

Multiubiquitin Chain Receptors Define a Layer of Substrate Selectivity in the Ubiquitin-Proteasome System

2004 • 450 citations

A proteasomal ATPase subunit recognizes the polyubiquitin degradation signal

2002 • 445 citations

RPN4 is a ligand, substrate, and transcriptional regulator of the 26S proteasome: A negative feedback circuit

2001 • 438 citations

An unstructured initiation site is required for efficient proteasome-mediated degradation

2004 • 434 citations

The Structure of the Protein Phosphatase 2A PR65/A Subunit Reveals the Conformation of Its 15 Tandemly Repeated HEAT Motifs

1999 • 434 citations

Autocatalytic Subunit Processing Couples Active Site Formation in the 20S Proteasome to Completion of Assembly

1996 • 390 citations

Rad23 and Rpn10 Serve as Alternative Ubiquitin Receptors for the Proteasome

2004 • 346 citations

Structural View of the Ran–Importin β Interaction at 2.3 Å Resolution

1999 • 344 citations

Hybrid Proteasomes

2000 • 342 citations

A role for the proteasome regulator PA28α in antigen presentation

1996 • 341 citations

Structure of the nuclear transport complex karyopherin-β2–Ran˙GppNHp

1999 • 340 citations

PA200, a nuclear proteasome activator involved in DNA repair

2002 • 313 citations

Inhibition of Proteasome Activity Induces Concerted Expression of Proteasome Genes and de Novo Formation of Mammalian Proteasomes

2003 • 309 citations

Structure of the Cand1-Cul1-Roc1 Complex Reveals Regulatory Mechanisms for the Assembly of the Multisubunit Cullin-Dependent Ubiquitin Ligases

2004 • 273 citations

Proteins Are Unfolded on the Surface of the ATPase Ring before Transport into the Proteasome

2001 • 235 citations

Proteasome Involvement in the Repair of DNA Double-Strand Breaks

2004 • 222 citations

Properties of the hybrid form of the 26S proteasome containing both 19S and PA28 complexes

2002 • 209 citations

Growth Retardation in Mice Lacking the Proteasome Activator PA28γ

1999 • 185 citations

Complementary Roles for Rpn11 and Ubp6 in Deubiquitination and Proteolysis by the Proteasome

2004 • 159 citations

cDNA Cloning, Expression, and Functional Characterization of PI31, a Proline-rich Inhibitor of the Proteasome

2000 • 132 citations

Review: Proteins with Repeated Sequence—Structural Prediction and Modeling

2001 • 119 citations

The pore of activated 20S proteasomes has an ordered 7-fold symmetric conformation

2003 • 118 citations

Blm3 is part of nascent proteasomes and is involved in a late stage of nuclear proteasome assembly

2003 • 113 citations

The role of the proteasome activator PA28 in MHC class I antigen processing

2002 • 109 citations

Regulatory mechanisms controlling biogenesis of ubiquitin and the proteasome

2004 • 82 citations

Structure and mechanism of ATP-dependent proteases

1999 • 73 citations

New HEAT-like repeat motifs in proteins regulating proteasome structure and function

2004 • 72 citations

Quaternary Structure of the ATPase Complex of Human 26S Proteasomes Determined by Chemical Cross-Linking

2001 • 72 citations

Conformational Remodeling of Proteasomal Substrates by PA700, the 19 S Regulatory Complex of the 26 S Proteasome

2002 • 72 citations

Proteasome activator (PA28) subunits, α, β and γ (Ki antigen) in NT2 neuronal precursor cells and HeLa S3 cells

1998 • 71 citations

Reconstitution of hybrid proteasomes from purified PA700–20 S complexes and PA28αβ activator: ultrastructure and peptidase activities

2001 • 69 citations

Yeast Cycloheximide-resistantcrlMutants Are Proteasome Mutants Defective in Protein Degradation

1997 • 67 citations

Proteasome degradation: enter the substrate

2003 • 60 citations

Further characterizations of bleomycin-sensitive (blm) mutants of Saccharomyces cerevisiae with implications for a radiomimetic model

1991 • 36 citations

Expression of the expanded YFL007w ORF and assignment of the gene name BLM10

2004 • 14 citations

Revisiting the yeast chromosome VI DNA sequence reveals a correction merging YFL007w and YFL006w to a single ORF

2002 • 6 citations

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