A proteasomal ATPase subunit recognizes the polyubiquitin degradation signal

THE UBIQUITIN SYSTEM

1998 • 8,360 citations

The 26S Proteasome: A Molecular Machine Designed for Controlled Proteolysis

1999 • 1,872 citations

Structure of ubiquitin refined at 1.8 Å resolution

1987 • 1,682 citations

Recognition of the polyubiquitin proteolytic signal

2000 • 1,651 citations

A Multiubiquitin Chain Is Confined to Specific Lysine in a Targeted Short-Lived Protein

1989 • 1,463 citations

A Subcomplex of the Proteasome Regulatory Particle Required for Ubiquitin-Conjugate Degradation and Related to the COP9-Signalosome and eIF3

1998 • 901 citations

A 26 S protease subunit that binds ubiquitin conjugates.

1994 • 759 citations

Proteasomal Proteomics: Identification of Nucleotide-sensitive Proteasome-interacting Proteins by Mass Spectrometric Analysis of Affinity-purified Proteasomes

2000 • 542 citations

The base of the proteasome regulatory particle exhibits chaperone-like activity

1999 • 485 citations

Ubiquitin in chains

2000 • 445 citations

Valosin-containing protein is a multi-ubiquitin chain-targeting factor required in ubiquitin–proteasome degradation

2001 • 431 citations

The Axial Channel of the Proteasome Core Particle Is Gated by the Rpt2 ATPase and Controls Both Substrate Entry and Product Release

2001 • 413 citations

The Multiubiquitin-Chain-Binding Protein Mcb1 Is a Component of the 26S Proteasome in Saccharomyces cerevisiae and Plays a Nonessential, Substrate-Specific Role in Protein Turnover

1996 • 393 citations

Inhibition of proteolysis and cell cycle progression in a multiubiquitination-deficient yeast mutant.

1994 • 347 citations

Active site mutants in the six regulatory particle ATPases reveal multiple roles for ATP in the proteasome

1998 • 306 citations

Surface hydrophobic residues of multiubiquitin chains essential for proteolytic targeting.

1996 • 240 citations

Multiple forms of the 20 S multicatalytic and the 26 S ubiquitin/ATP-dependent proteases from rabbit reticulocyte lysate.

1992 • 229 citations

Inhibition of the 26 S Proteasome by Polyubiquitin Chains Synthesized to Have Defined Lengths

1997 • 229 citations

Recognition of Misfolding Proteins by PA700, the Regulatory Subcomplex of the 26 S Proteasome

2000 • 191 citations

A protein–protein interaction map of the Caenorhabditis elegans 26S proteasome

2001 • 180 citations

Multiubiquitin Chain Binding and Protein Degradation Are Mediated by Distinct Domains within the 26 S Proteasome Subunit Mcb1

1998 • 174 citations

Structure of Tetraubiquitin Shows How Multiubiquitin Chains Can Be Formed

1994 • 151 citations

Identification, Purification, and Characterization of a PA700-dependent Activator of the Proteasome

1996 • 138 citations

Quantitative Analysis of the Isolated GAAA Tetraloop/Receptor Interaction in Solution: A Site-Directed Spin Labeling Study

2001 • 115 citations

The Hydrophobic Effect Contributes to Polyubiquitin Chain Recognition

1998 • 112 citations

Bicarbonate Is Required for the Peroxidase Function of Cu,Zn-Superoxide Dismutase at Physiological pH

1999 • 91 citations

Quaternary Structure of the ATPase Complex of Human 26S Proteasomes Determined by Chemical Cross-Linking

2001 • 72 citations

Nucleotidase Activities of the 26 S Proteasome and Its Regulatory Complex

1996 • 57 citations