Interaction of antibodies with renal cell surface antigens

A Receptor-Mediated Pathway for Cholesterol Homeostasis

1986 • 5,638 citations

Receptor-Mediated Endocytosis: Concepts Emerging from the LDL Receptor System

1985 • 1,585 citations

Overlapping patterns of activation of human endothelial cells by interleukin 1, tumor necrosis factor, and immune interferon.

1986 • 1,439 citations

YOLK PROTEIN UPTAKE IN THE OOCYTE OF THE MOSQUITO AEDES AEGYPTI. L

1964 • 1,298 citations

Antigen-Presenting Function of the Macrophage

1984 • 1,164 citations

The Golgi apparatus (complex)-(1954-1981)-from artifact to center stage.

1981 • 990 citations

LYSOSOME FUNCTION IN THE REGULATION OF THE SECRETORY PROCESS IN CELLS OF THE ANTERIOR PITUITARY GLAND

1966 • 951 citations

Clathrin: a unique protein associated with intracellular transfer of membrane by coated vesicles.

1976 • 663 citations

Production of Nephrotic Syndrome in Rats by Freund's Adjuvants and Rat Kidney Suspensions.

1959 • 622 citations

Immune Complex Disease in Experimental Animals and Man

1973 • 619 citations

Epithelial cytoskeletal framework and nuclear matrix-intermediate filament scaffold: three-dimensional organization and protein composition.

1984 • 545 citations

The pathogenic antigen of Heymann nephritis is a membrane glycoprotein of the renal proximal tubule brush border.

1982 • 539 citations

Immunocytochemical localization of the Heymann nephritis antigen (GP330) in glomerular epithelial cells of normal Lewis rats

1983 • 496 citations

Mutation in LDL Receptor: Alu-Alu Recombination Deletes Exons Encoding Transmembrane and Cytoplasmic Domains

1985 • 453 citations

The release of platelet-activating factor from human endothelial cells in culture.

1983 • 436 citations

Experimental glomerulonephritis in the isolated perfused rat kidney.

1978 • 386 citations

[Angiotensin-I converting enzyme].

1995 • 335 citations

Experimental glomerulonephritis in the rat induced by antibodies directed against tubular antigens. V. Fixed glomerular antigens in the pathogenesis of heterologous immune complex glomerulonephritis.

1978 • 324 citations

Role of coated vesicles, microfilaments, and calmodulin in receptor-mediated endocytosis by cultured B lymphoblastoid cells.

1980 • 315 citations

AUTOLOGOUS IMMUNE COMPLEX NEPHRITIS INDUCED WITH RENAL TUBULAR ANTIGEN

1968 • 315 citations

A new role for complement in experimental membranous nephropathy in rats.

1980 • 303 citations

Endocytosis: Relation to Capping and Cell Locomotion

1984 • 292 citations

Uromodulin (Tamm-Horsfall Glycoprotein): a Renal Ligand for Lymphokines

1987 • 278 citations

Induction of Membranous Nephropathy in Rabbits by Administration of an Exogenous Cationic Antigen

1982 • 264 citations

Glomerulonephritis induced by monoclonal anti-Thy 1.1 antibodies. A sequential histological and ultrastructural study in the rat.

1986 • 262 citations

Involvement of vesicle coat material in casein secretion and surface regeneration.

1976 • 256 citations

Induction of anti-glomerular basement membrane antibodies in the Brown-Norway rat by mercuric chloride.

1977 • 221 citations

Endothelial cell membranes contain podocalyxin--the major sialoprotein of visceral glomerular epithelial cells.

1986 • 207 citations

Autologous Immune-Complex Pathogenesis of Experimental Allergic Glomerulonephritis

1967 • 205 citations

Rat brain Thy-1 glycoprotein. The amino acid sequence, disulphide bonds and an unusual hydrophobic region

1981 • 203 citations

Inhibition and reversal of capping by cytochalasin B, yinblastine and colchicine

1974 • 188 citations

Tamm-Horsfall glycoprotein: ultrastructural immunoperoxidase localization in rat kidney.

1979 • 185 citations

Regulation of low-density lipoprotein receptors: implications for pathogenesis and therapy of hypercholesterolemia and atherosclerosis.

1987 • 177 citations

Actin and tubulin co-cap with surface immunoglobulins in mouse B lymphocytes

1977 • 177 citations

Microdomains of distinctive glycoprotein composition in the kidney proximal tubule brush border.

1984 • 174 citations

Mechanisms of glomerular injury in immune-complex disease

1985 • 172 citations

Induction and Suppression of Polyclonal Antibody Responses by Anti‐Ig Reagents and Antigen‐Nonspecific Helper Factors:

1980 • 169 citations

Angiotensin I converting enzyme in human intestine and kidney

1986 • 166 citations

Complement-induced glomerular epithelial cell injury. Role of the membrane attack complex in rat membranous nephropathy.

1986 • 166 citations

Angiotensin I‐converting Enzyme

1986 • 164 citations

Initial events in the formation of immune deposits in passive Heymann nephritis. gp330-anti-gp330 immune complexes form in epithelial coated pits and rapidly become attached to the glomerular basement membrane.

1987 • 164 citations

Modification of the antigenic structure of the cell membrane by thymus-leukemia (TL) antibody.

1967 • 160 citations

Basement membrane heparan sulfate proteoglycans are concentrated in the laminae rarae and in podocytes of the rat renal glomerulus.

1985 • 154 citations

Complement dependence of antibody-induced mesangial cell injury in the rat.

1987 • 143 citations

Three distinct classes of regulatory cytokines control endothelial cell MHC antigen expression. Interactions with immune gamma interferon differentiate the effects of tumor necrosis factor and lymphotoxin from those of leukocyte alpha and fibroblast beta interferons.

1988 • 142 citations

Elimination of terminal complement intermediates from the plasma membrane of nucleated cells: the rate of disappearance differs for cells carrying C5b-7 or C5b-8 or a mixture of C5b-8 with a limited number of C5b-9.

1985 • 139 citations

Characterization of a 280-kD protein restricted to the coated pits of the renal brush border and the epithelial cells of the yolk sac. Teratogenic effect of the specific monoclonal antibodies.

1988 • 137 citations

Two distinct mechanisms for redistribution of lymphocyte surface macromolecules. I. Relationship to cytoplasmic myosin.

1978 • 132 citations

Ultrastructural localization by monoclonal antibodies of brush border antigens expressed by glomeruli. II. Extrarenal distribution.

1986 • 131 citations

Ligand-induced association of surface immunoglobulin with the detergent-insoluble cytoskeletal matrix of the B lymphocyte.

1982 • 124 citations

Involvement of Plasma Membrane Dipeptidyl Peptidase IV in Fibronectin-Mediated Adhesion of Cells on Collagen

1985 • 124 citations

Actin co-caps with concanavalin A receptors

1977 • 124 citations

Antibody-induced redistribution of Heymann antigen on the surface of cultured glomerular visceral epithelial cells: possible role in the pathogenesis of Heymann glomerulonephritis.

1985 • 113 citations

Characterization of the antigen (gp600) of Heymann nephritis.

1984 • 108 citations

Ultrastructural localization of Tamm-Horsfall glycoprotein (THP) in rat kidney as revealed by protein A-gold immunocytochemistry

1985 • 108 citations

EXPERIMENTAL ALLERGIC GLOMERULONEPHRITIS INDUCED IN THE RABBIT WITH HETEROLOGOUS RENAL ANTIGENS

1967 • 105 citations

Nephropathy associated with sickle cell anemia: An autologous immune complex nephritis

1975 • 102 citations

Mercuric chloride induced autoimmune disease in Brown‐Norway rats: sequential search for anti‐basement membrane antibodies and circulating immune complexes

1982 • 98 citations

Tubulointerstitial immune complex nephritis in rats immunized with Tamm-Horsfall protein

1980 • 97 citations

Internalization of lymphocyte membrane components

1985 • 94 citations

Human renal transplants. 3. Immunopathologic studies.

1970 • 93 citations

A monoclonal antibody to brush border and passive Heymann nephritis.

1984 • 92 citations

Identification of a major sialoprotein in the glycocalyx of human visceral glomerular epithelial cells.

1986 • 92 citations

Production of Congenital Malformations Using Tissue Antibodies. I. Kidney Antisera.

1961 • 89 citations

The Induction of Acute Glomerulonephritis in Rabbits with Soluble Antigens Isolated from Normal Homologous and Autologous Urine

1968 • 89 citations

Comodulation of CD3 and CD4. Evidence for a specific association between CD4 and approximately 5% of the CD3:T cell receptor complexes on helper T lymphocytes.

1988 • 89 citations

Effects of prolonged administration of d-penicillamine or captopril in various strains of rats

1984 • 88 citations

Membranous nephropathy due to skin-lightening cream.

1974 • 86 citations

How Receptors Bring Proteins and Particles into Cells

1984 • 85 citations

Experimental autoimmune nephrosis in rats. Morphogenesis of the glomerular lesion: immunohistochemical and electron microscopic studies.

1969 • 84 citations

The membrane composition of coated pits, microvilli, endosomes, and lysosomes is distinctive in the rat kidney proximal tubule cell.

1986 • 81 citations

Membranous glomerulonephritis in the mouse

1983 • 81 citations

Regional distribution of N-acetyl-D-galactosamine residues in the glycocalyx of glomerular podocytes.

1983 • 81 citations

Hyperacute renal allograft rejection in the rabbit. The role of platelet-activating factor and of cationic proteins derived from polymorphonuclear leukocytes and from platelets.

1984 • 80 citations

Glomerulonephritis induced in the rabbit by antiendothelial antibodies.

1987 • 77 citations

Formation of immune deposits and disease.

1986 • 77 citations

Studies on multiple renal lesions in Heymann nephritis.

1971 • 76 citations

Antibody-mediated injury to proximal tubules in Heymann nephritis

1980 • 76 citations

Antigenic modulation - a major mechanism of antibody action

1984 • 76 citations

Nonglomerular renal disease produced in rabbits by immunization with homologous kidney.

1971 • 75 citations

Deposition of Renal Tubular Epithelial Antigen Along the Glomerular Capillary Walls of Patients with Membranous Glomerulonephritis

1973 • 73 citations

Nephrotic Syndrome After Contact with Mercury

1962 • 71 citations

Passive transfer of Heymann nephritis with serum

1973 • 68 citations

EXPERIMENTAL ALLERGIC GLOMERULONEPHRITIS INDUCED IN THE RABBIT WITH HOMOLOGOUS RENAL ANTIGENS

1967 • 65 citations

The membrane attack complex in complement-mediated glomerular epithelial cell injury: formation and stability of C5b-9 and C5b-7 in rat membranous nephropathy.

1986 • 65 citations

Induction of an autologous immune-complex glomerulonephritis in the rat by intravenous injection of heterologous anti-rat kidney tubular antibody. I. Production of chronic progressive immune-complex glomerulonephritis.

1974 • 64 citations

Thy-1.1 in glomeruli of rat kidneys

1984 • 62 citations

I. Induction of proteinuria in the rat by a monoclonal antibody against SGP-115/107

1988 • 62 citations

Detection of terminal complement components in experimental immune glomerular injury

1984 • 62 citations

Gametes contain angiotensin converting enzyme (kininase II)

1986 • 62 citations

An immunopathologic study of a 330-kD protein defined by monoclonal antibodies and reactive with anti-RTE alpha 5 antibodies and kidney eluates from active Heymann nephritis.

1986 • 61 citations

Identification of a 400-kd protein in the brush borders of human kidney tubules that is similar to gp330, the nephritogenic antigen of rat Heymann nephritis.

1987 • 61 citations

Endocytosis of the C3b receptor of complement within coated pits in human polymorphonuclear leukocytes and monocytes.

1983 • 60 citations

Characterization of antigens and antibody specificities involved in Heymann nephritis.

1985 • 59 citations

Receptor‐Mediated Transport of IgG Across the Intestinal Epithelium of the Neonatal Rat

1982 • 58 citations

Studies on the formation of glomerular immune deposits in Brown Norway rats injected with mercuric chloride

1987 • 58 citations

Endogenous immune complex nephropathy associated with malignancy I. Studies on the nature and immunopathogenic significance of glomerular bound antigen and antibody, isolation and characterization of tumor specific antigen and antibody and circulating immune complexes.

1975 • 57 citations

Podoendin. A new cell surface protein of the podocyte and endothelium.

1985 • 57 citations

The C1q subunit of the first component of complement binds to laminin: a mechanism for the deposition and retention of immune complexes in basement membrane.

1985 • 55 citations

Lung injury mediated by antibodies to endothelium. I. In the rabbit a repeated interaction of heterologous anti-angiotensin-converting enzyme antibodies with alveolar endothelium results in resistance to immune injury through antigenic modulation.

1983 • 55 citations

Heymann nephritis induced by kidney brush border glycoproteins.

1980 • 55 citations

Epithelial polyanion (podocalyxin) is found on the sides but not the soles of the foot processes of the glomerular epithelium.

1986 • 55 citations

Oxidative cross-linking of immune complexes by human polymorphonuclear leukocytes.

1988 • 50 citations

Preferential distribution of surface immunoglobulins on microvilli

1978 • 50 citations

B Lymphocyte Biology Studied with Anti‐Ig Antibodies

1980 • 50 citations

Influence of antigen distribution on the mediation of immunological glomerular injury

1985 • 50 citations

Possible involvement of terminal complement complex in active Heymann nephritis

1985 • 47 citations

Evidence of Autologous Immune-Complex Nephritis

1981 • 46 citations

In vivo interaction of antibodies with cell surface antigens. A mechanism responsible for in situ formation of immune deposits in the zona pellucida of rabbit oocytes.

1985 • 45 citations

Receptor-Mediated Endocytosis and Intracellular Processing of Insulin: Ultrastructural and Biochemical Evidence for Cell-Specific Heterogeneity and Distinction from Nonhormonal Ligands

1989 • 44 citations

Capping of exogenous Forssman glycolipid on cells.

1979 • 44 citations

Pathogenesis of passive Heymann glomerulonephritis: chlorpromazine inhibits antibody-mediated redistribution of cell surface antigens and prevents development of the disease.

1986 • 42 citations

Heymann antibodies induce complement-dependent injury of rat glomerular visceral epithelial cells.

1987 • 42 citations

The disruption of immunoglobulin caps by local anesthetics

1976 • 42 citations

Absence of glomerular renal tubular epithelial antigen in membranous glomerulonephritis.

1976 • 42 citations

Simultaneous anti-glomerular basement membrane and membranous glomerulonephritis: Case report and literature review

1984 • 41 citations

Diagnostic Immunopathology

1989 • 40 citations

Pathogenesis of arteritis of SL/Ni mice. Possible lytic effect of anti-gp70 antibodies on vascular smooth muscle cells.

1987 • 40 citations

Suppression of Rejection of Organ Allografts by Alloantibody*

1980 • 40 citations

Genetically Controlled Autologous Immune Complex Glomerulonephritis in Rats

1975 • 39 citations

Genetic control of susceptibility to autologous immune complex glomerulonephritis in inbred rat strains.

1978 • 38 citations

Polyvalent antigen-antibody interactions are required for the formation of electron-dense immune deposits in passive Heymann's nephritis.

1986 • 37 citations

Anti-basement membrane glomerulopathy in experimental trypanosomiasis.

1987 • 36 citations

Antibody-mediated injury to proximal tubules in the rat kidney induced by passive transfer of homologous anti-brush border serum

1981 • 34 citations

Comparison of antigenic targets involved in antibody-mediated membranous glomerulonephritis in the mouse and rat.

1985 • 34 citations

Antibodies to purified renal tubular epithelial antigens contain activity against laminin, fibronectin, and type IV collagen.

1988 • 34 citations

Specific uptake of Heymann's nephritic kidney eluate by rat kidney: studies in vivo and in isolated perfused kidneys.

1982 • 32 citations

The Structural Proteins of Murine Leukemia Virus and the Pathogenesis of Necrotizing Arteritis and Glomerulonephritis in SL/Ni Mice

1979 • 32 citations

Circulating immune complexes in rats with autologous immune complex nephritis.

1980 • 31 citations

II. Epitope specific induction of proteinuria by monoclonal antibodies

1988 • 30 citations

Immune Mechanisms in Renal Disease

1983 • 30 citations

Identification of gp108, a pathogenic antigen of passive Heymann nephritis, as dipeptidyl peptidase IV.

1987 • 30 citations

Ultrastructural studies of tubulointerstitial immune complex nephritis in rats immunized with Tamm-Horsfall protein.

1981 • 29 citations

Membranous Nephropathy: A Radioimmunologic Search for Anti-Renal Tubular Epithelial Antibodies and Circulating Immune Complexes

1979 • 29 citations

Immunopathogenesis of Heymann's nephritis

1984 • 29 citations

Isolation, partial characterization, and localization of a rat renal tubular glycoprotein antigen. Antibody-induced birth defects.

1982 • 29 citations

Transplantation-induced immune complex kidney disease in rats with unilateral manifestation in the allografted kidney.

1979 • 28 citations

Immunoregulation of Heymann's nephritis. I. Induction of suppressor cells.

1979 • 28 citations

Evaluation of sequential glomerular eluates from rats with Heymann nephritis.

1986 • 28 citations

Immunologically mediated lesions of kidney tubules and interstitium in laboratory animals and in man

1982 • 28 citations

MERCURY AND THE KIDNEY

1963 • 28 citations

Antigens in human renal allografts

1981 • 27 citations

Lack of Evidence for a Role of Renal Tubular Antigen in Human Membranous Glomerulonephritis

1981 • 27 citations

Autoimmune concomitants of renal allografts.

1969 • 26 citations

Renal tubular immune complex formation in mice immunized with Tamm-Horsfall protein.

1986 • 26 citations

The autoimmune response in active Heymann's nephritis in Lewis rats is regulated by T-lymphocyte subsets

1985 • 25 citations

Presence of antibodies against a cell-surface protein, cross-reactive with DNA, in systemic lupus erythematosus: a marker of the disease.

1987 • 25 citations

Studies of the antigens involved in an immunologic renal tubular lesion in rabbits.

1977 • 25 citations

A new glomerular antigen in passive Heymann's nephritis.

1984 • 23 citations

Formation and clearance of tubulointerstitial immune complexes in kidneys of rats immunized with heterologous antisera to Tamm-Horsfall protein

1982 • 23 citations

The effect of puromycin on subepithelial deposits induced by antibodies directed against tubular antigens: a quantitative study*

1979 • 22 citations

Immune-mediated injury to basement membranes in mice immunized with murine laminin

1984 • 22 citations

Differential interaction of the C3b/C4b receptor and MHC class I with the cytoskeleton of human neutrophils.

1986 • 22 citations

Demonstration of a passive Heymann nephritis-like mechanism in a human kidney transplant.

1981 • 22 citations

Antigenic targets in membranous glomerulonephritis

1987 • 20 citations

<b>The presence of Thy-1-1 antigen in rat glomerular mesangial </b><b>cells </b>

1980 • 20 citations

The specificity of nephritogenic antibodies. III. Binding of anti-Fx1A antibodies in glomeruli is dependent on dual specificity.

1986 • 19 citations

Passively transferred anti-brush border antibodies induce injury of proximal tubules in the absence of complement.

1984 • 19 citations

The pathogenesis of extrarenal lesions in systemic lupus erythematosus

1982 • 18 citations

Tubulointerstitial nephritis in rabbits challenged with homologous Tamm-Horsfall protein: the role of endotoxin.

1983 • 18 citations

Circulatory antigen of Heymann nephritis. II. Isolation of a 70,000 MW antigen from normal rat serum which cross-reacts with Heymann nephritis antigen.

1986 • 16 citations

Heymann nephritis in rats induced by human renal tubular antigens: characterization of antigen and antibody specificities.

1987 • 15 citations

Immune-complex disease with unilateral renal vein thrombosis.

1976 • 15 citations

Induction of autologous immune complex nephritis in rats by heterologous anti-kidney mitochondrial antiserum

1970 • 14 citations

Reestablishment of self tolerance by suppressor T-cells after active Heymann's nephritis

1986 • 14 citations

Anti-Fx1A induces association of Heymann nephritis antigens with microfilaments of cultured glomerular visceral epithelial cells.

1987 • 13 citations

Influence of altered glomerular permeability on renal tubular immune complex formation and clearance.

1983 • 13 citations

Control of autologous immune complex nephritis. I. Suppression of the disease in the presence of T cell sensitization.

1980 • 13 citations

Regional heterogeneity of glycoconjugate distribution in the glomerulus revealed by lectin-gold cytochemistry and SDS-PAGE.

1986 • 12 citations

THE SPECIFICITY OF NEPHRITOGENIC ANTIBODIES

1986 • 11 citations

Biochemical investigation of the pathogenesis of Heymann Nephritis

1986 • 11 citations

[T lymphocytes functions in mercuric chloride-induced membranous glomerulonephritis in man. Evidence for a defect of presentation of the histocompatibility class II molecules at the cell surface (author's transl)].

1981 • 10 citations

Glomerular and vascular IgG deposits in HgCl2 nephritis: Role of circulating antibodies and of immune complexes

1983 • 10 citations

Surface immunoglobulin and the lymphocyte cytoskeleton.

1983 • 9 citations

Lymphocyte expression of a 90 kD brush border antigen.

1987 • 9 citations

Antibody-mediated proliferation of proximal tubule cells.

1988 • 9 citations

IMMUNOGENICITY OF THE NON-MHC-ENCODED ENDOTHELIAL ANTIGEN EAG-1 IN VARIOUS TISSUES OF THE RAT

1987 • 8 citations

Impaired Organic Ion Transport in Proximal Tubules of Rats with Heymann Nephritis

1985 • 8 citations

Effect of chlorpromazine on the development of experimental glomerulonephritis and Arthus reaction.

1988 • 7 citations

Tubular antigen-associated renal disease in New Zealand white rabbits.

1986 • 7 citations

THE SPECIFICITY OF NEPHRITOGENIC ANTIBODIES

1984 • 7 citations

Influence of Renal Transplantation in Rats on Glomerular and Tubular Immune Complexes

1986 • 7 citations

Analysis of the Heymann nephritogenic glycoprotein in rat, mouse, and human kidney

1986 • 7 citations

Congenital Abnormalities Induced by Heterologous Antisera Directed Against Rat Kidney Glycoproteins Isolated by Concanavalin A Affinity Chromatography

1979 • 7 citations

Renal tubule brush border antigens: failure to confirm a pathogenetic role in human membranous glomerulonephritis.

1980 • 6 citations

Autoimmune Disease Induced in Rabbits by Administration of Mercuric Chloride: Evidence Suggesting a Role for Antigens of the Connective Tissue Matrix

1983 • 6 citations

MEMBRANE IgD EXPRESSION AND DYNAMICS IN CLONES OF HUMAN B‐LYMPHOBLASTOID CELLS*

1982 • 6 citations

Passive Heymann-like nephritis in the rabbit.

1985 • 5 citations

The Role of Circulating Antigen in the Formation of Immune Deposits in Experimental Membranous Nephropathy

1986 • 5 citations

Antibody-mediated proliferation of proximal tubule cells requires cross-linking of antigenic determinants.

1988 • 3 citations

Deleted Work

1955 • 0 citations