Comparison of doxorubicin‐induced DNA damage in doxorubicin‐sensitive and ‐resistant P388 murine leukemia cells

Adriamycin-Induced DNA Damage Mediated by Mammalian DNA Topoisomerase II

1984 • 1,477 citations

Cell Surface P-Glycoprotein Associated with Multidrug Resistance in Mammalian Cell Lines

1983 • 1,001 citations

Fractionation of DNA from mammalian cells by alkaline elution

1976 • 838 citations

DNA repair: a laboratory manual of research procedures

1981 • 818 citations

Increased accumulation of vincristine and adriamycin in drug-resistant P388 tumor cells following incubation with calcium antagonists and calmodulin inhibitors.

1982 • 667 citations

Mechanism of antitumor drug action: poisoning of mammalian DNA topoisomerase II on DNA by 4'-(9-acridinylamino)-methanesulfon-m-anisidide.

1984 • 559 citations

The genetic origin of drug resistance in neoplasms: implications for systemic therapy.

1984 • 521 citations

Role of topoisomerase II in mediating epipodophyllotoxin-induced DNA cleavage.

1984 • 463 citations

Cancer: Principles and Practice of Oncology

1983 • 456 citations

Reversal of Adriamycin Resistance by Verapamil in Human Ovarian Cancer

1984 • 398 citations

Amplification of specific DNA sequences correlates with multi-drug resistance in Chinese hamster cells

1984 • 340 citations

Qualitative and quantitative aspects of intercalator-induced DNA strand breaks

1979 • 244 citations

The james ewing lecture. The relationship between tumor mass and resistance to chemotherapy. Implications for surgical adjuvant treatment of cancer

1983 • 230 citations

Uptake and retention of adriamycin and daunorubicin by sensitive and anthracycline-resistant sublines of P388 leukemia

1978 • 212 citations

Inhibition of DNA and RNA metabolism by daunorubicin and adriamycin in L1210 mouse leukemia.

1972 • 166 citations

In vivo characteristics of resistance and cross-resistance of an adriamycin-resistant subline of P388 leukemia.

1978 • 135 citations

Enhancement of vincristine- and adriamycin-induced cytotoxicity by verapamil in P388 leukemia and its sublines resistant to vincristine and adriamycin

1982 • 132 citations

Carrier-mediated transport of daunorubicin, adriamycin, and rubidazone in ehrlich ascites tumour cells

1978 • 121 citations

Tumour cell resistance to anthracyclines ? A review

1985 • 120 citations

Cellular pharmacodynamics of several anthracycline antibiotics

1976 • 109 citations

Drug resistance in Chinese hamster lung and mouse tumor cells.

1983 • 105 citations

The interaction of daunorubicin and doxorubicin with DNA and chromatin

1980 • 104 citations

Restoration of doxorubicin responsiveness in doxorubicin-resistant P388 murine leukaemia cells

1984 • 86 citations

Mechanisms of Selective Cytotoxicity of Adriamycin, Daunomycin and Related Anthracyclines

1983 • 12 citations

Podophyllotoxin and VP-16-213: a review of their divergent mechanisms of action

1984 • 10 citations