The Adverse Pial Arteriolar and Axonal Consequences of Traumatic Brain Injury Complicated by Hypoxia and Their Therapeutic Modulation with Hypothermia in Rat

A new model of diffuse brain injury in rats

1994 • 1,177 citations

Glutamate Release and Free Radical Production Following Brain Injury: Effects of Posttraumatic Hypothermia

1995 • 616 citations

Multivariable Prognostic Analysis in Traumatic Brain Injury: Results from The IMPACT Study

2007 • 597 citations

Prognostic Value of Secondary Insults in Traumatic Brain Injury: Results from The IMPACT Study

2007 • 382 citations

Functional, morphological, and metabolic abnormalities of the cerebral microcirculation after concussive brain injury in cats.

1980 • 290 citations

Hypothermia Treatment for Traumatic Brain Injury: A Systematic Review and Meta-Analysis

2008 • 255 citations

Detailed Description of a Cranial Window Technique for Acute and Chronic Experiments

1975 • 222 citations

Inhibition by free radical scavengers and by cyclooxygenase inhibitors of pial arteriolar abnormalities from concussive brain injury in cats.

1981 • 222 citations

Effect of Long-Term Mild Hypothermia or Short-Term Mild Hypothermia on Outcome of Patients with Severe Traumatic Brain Injury

2005 • 193 citations

Impact acceleration injury in the rat: evidence for focal axolemmal change and related neurofilament sidearm alteration.

1997 • 186 citations

The importance of brain temperature in cerebral injury.

1992 • 170 citations

Impact Acceleration Injury in the Rat

1997 • 157 citations

Protection in Animal Models of Brain and Spinal Cord Injury with Mild to Moderate Hypothermia

2009 • 140 citations

Posttraumatic hypothermia in the treatment of axonal damage in an animal model of traumatic axonal injury

1998 • 139 citations

Relationship between body and brain temperature in traumatically brain-injured rodents

1991 • 126 citations

Adding insult to injury: the prognostic value of early secondary insults for survival after traumatic brain injury

1999 • 123 citations

Effect of Hypoxia on Traumatic Brain Injury in Rats: Part 1

1987 • 123 citations

Quantitative Analysis of the Relationship between Intra- Axonal Neurofilament Compaction and Impaired Axonal Transport following Diffuse Traumatic Brain Injury

2005 • 103 citations

Exacerbation of traumatically induced axonal injury by rapid posthypothermic rewarming and attenuation of axonal change by cyclosporin A

2001 • 100 citations

Posthypothermic Rewarming Considerations following Traumatic Brain Injury

2009 • 94 citations

Posttraumatic hypothermia is neuroprotective in a model of traumatic brain injury complicated by a secondary hypoxic insult

2001 • 92 citations

Posttraumatic Hypothermia followed by Slow Rewarming Protects the Cerebral Microcirculation

2003 • 90 citations

The visualization of a new class of traumatically injured axons through the use of a modified method of microwave antigen retrieval

1999 • 89 citations

Endothelium-Dependent Responses After Experimental Brain Injury

1992 • 83 citations

Neuroprotective Effect of Hypothermia on Neuronal Injury in Diffuse Traumatic Brain Injury Coupled With Hypoxia and Hypotension

1999 • 83 citations

Effect of Hypoxia on Traumatic Brain Injury in Rats: Part 2

1987 • 75 citations

In vivo bioassay of endothelium-derived relaxing factor

1988 • 61 citations

Multicenter Trial of Early Hypothermia in Severe Brain Injury

2009 • 59 citations

Effects in cats of inhibition of nitric oxide synthesis on cerebral vasodilation and endothelium-derived relaxing factor from acetylcholine.

1992 • 47 citations

Posttraumatic brain vulnerability to hypoxia-hypotension: the importance of the delay between brain trauma and secondary insult

2007 • 41 citations

Effect of Mild Hypothermia on Brain Dialysate Lactate after Fluid Percussion Brain Injury in Rodents

2004 • 38 citations

No long-term benefit from hypothermia after severe traumatic brain injury with secondary insult in rats

2000 • 37 citations

Clinical Study of Mild Hypothermia Treatment for Severe Traumatic Brain Injury

2009 • 32 citations

Current status of cerebral protection with mild-to-moderate hypothermia after traumatic brain injury

2007 • 32 citations

The effect of PGF2a on in vivo cerebral arteriolar diameter in cats and rats

1983 • 26 citations

Secondary injury in traumatic brain injury patients--a prospective study.

2002 • 20 citations

Changes in the Cerebral Vasculature after Hypertension and Trauma: A Combined Scanning and Transmission Electron Microscopic Analysis

1980 • 17 citations

Therapeutische Hypothermie

2008 • 11 citations

Influences of Secondary Injury Following Traumatic Brain Injury in Developing Versus Adult Rats

2000 • 6 citations

Combat hypoxia: the importance of airway management & oxygenation of the traumatic brain injury patient.

2003 • 3 citations