The visualization of a new class of traumatically injured axons through the use of a modified method of microwave antigen retrieval

Antigen retrieval in formalin-fixed, paraffin-embedded tissues: an enhancement method for immunohistochemical staining based on microwave oven heating of tissue sections.

1991 • 2,598 citations

A new model of diffuse brain injury in rats

1994 • 1,177 citations

Diffuse axonal injury due to nonmissile head injury in humans: An analysis of 45 cases

1982 • 930 citations

DIFFUSE DEGENERATION OF THE CEREBRAL WHITE MATTER IN SEVERE DEMENTIA FOLLOWING HEAD INJURY

1956 • 719 citations

β-Amyloid precursor protein (βAPP) as a marker for axonal injury after head injury

1993 • 557 citations

A new model of diffuse brain injury in rats

1994 • 528 citations

Stalning af amyloid percursor protein to study axonal damage in mild head Injury

1994 • 456 citations

Axonal Change in Minor Head Injury

1983 • 435 citations

Traumatically induced axonal injury: pathogenesis and pathobiological implications.

1992 • 408 citations

Early detection of axonal injury after human head trauma using immunocytochemistry for ?-amyloid precursor protein

1994 • 348 citations

Topography of Axonal Injury as Defined by Amyloid Precursor Protein and the Sector Scoring Method in Mild and Severe Closed Head Injury

1995 • 345 citations

Traumatically Induced Altered Membrane Permeability: Its Relationship to Traumatically Induced Reactive Axonal Change

1994 • 316 citations

Axonal injury: a universal consequence of fatal closed head injury?

1995 • 279 citations

Characterization of a distinct set of intra-axonal ultrastructural changes associated with traumatically induced alteration in axolemmal permeability

1996 • 248 citations

Ultrastructural Studies of Diffuse Axonal Injury in Humans

1994 • 244 citations

Pathobiology of traumatically induced axonal injury in animals and man

1993 • 243 citations

Immunohistochemical characterization of alterations in the distribution of amyloid precursor proteins and beta-amyloid peptide after experimental brain injury in the rat

1996 • 242 citations

Temporal and Regional Patterns of Axonal Damage following Traumatic Brain Injury

1997 • 229 citations

Markers of axonal injury in post mortem human brain

1994 • 226 citations

The Use of Antibodies Targeted Against the Neurofilament Subunits for the Detection of Diffuse Axonal Injury in Humans

1993 • 196 citations

Impact acceleration injury in the rat: evidence for focal axolemmal change and related neurofilament sidearm alteration.

1997 • 186 citations

Is β-APP a marker of axonal damage in short-surviving head injury?

1996 • 186 citations

Traumatically Induced Reactive Change as Visualized Through the Use of Monoclonal Antibodies Targeted to Neurofilament Subunits

1992 • 172 citations

Shear injuries of the brain.

1967 • 160 citations

Axonal response to traumatic brain injury: reactive axonal change, deafferentation, and neuroplasticity.

1992 • 157 citations

The amyloid precursor protein is concentrated in neuronal lysosomes in normal and Alzheimer disease subjects

1989 • 142 citations

Traumatically Induced Axonal Damage: Evidence for Enduring Changes in Axolemmal Permeability with Associated Cytoskeletal Change

1996 • 132 citations

Trafficking of cell-surface amyloid β-protein precursor: II. Endocytosis, recycling, and lysosomal targeting detected by immunolocalization

1996 • 132 citations

The diagnosis of diffuse axonal injury: implications for forensic practice

1997 • 123 citations

Effects of antigen retrieval by microwave heating in formalin-fixed tissue sections on a broad panel of antibodies

1994 • 95 citations

Neuropathological Changes in the White Matter Following Head Injury^*

1967 • 94 citations

Changes in microtubule-associated protein 2 and amyloid precursor protein immunoreactivity following traumatic brain injury in rat: influence of MK-801 treatment

1996 • 94 citations

A Head Impact Model of Early Axonal Injury in the Sheep

1996 • 92 citations

Traumatic brain injury in rat produces changes of β-amyloid precursor protein immunoreactivity

1995 • 90 citations

Immunohistochemical localization of beta‐amyloid precursor protein sequences in Alzheimer and normal brain tissue by light and electron microscopy

1992 • 88 citations

Characterization of a prolonged regenerative attempt by diffusely injured axons following traumatic brain injury in adult cat: a light and electron microscopic immunocytochemical study

1997 • 82 citations

Microwave fixation: Understanding the variables to achieve rapid reproducible results

1995 • 76 citations

Localization of amyloid precursor protein in selective postsynaptic densities of rat cortical neurons

1992 • 70 citations

Changes of β-Amyloid Precursor Protein after Compression Trauma to the Spinal Cord: An Experimental Study in the Rat Using Immunohistochemistry

1995 • 68 citations

Accumulation of β-amyloid precursor protein and ubiquitin in axons after spinal cord trauma in humans: immunohistochemical observations on autopsy material

1996 • 65 citations

Subcellular localization of amyloid precursor protein in senile plaques of Alzheimer's disease.

1992 • 58 citations

Alteration of immunoreactivity by hydrated autoclaving, microwave treatment, and simple heating of paraffin-embedded tissue sections

1994 • 58 citations

β-Amyloid precursor protein localization in the Golgi apparatus in neuron and oligodendrocytes. An immunocytochemical structural and ultrastructural study in normal and axotomized neurons

1992 • 53 citations

Ultrastructural localization of Alzheimer amyloid ?/A4 protein precursor in the cytoplasm of neurons and senile plaque-associated astrocytes

1992 • 53 citations

Methods of microwave fixation for microscopy. A review of research and clinical applications: 1970-1992.

1994 • 45 citations

Axonal Injury in Falls

1997 • 44 citations

Microwave antigen retrieval of β-amyloid precursor protein immunoreactivity

1994 • 43 citations

White matter damage following acute head injury

1987 • 28 citations

Origin of beading constrictions at the axolemma: Presence in unmyelinated axons and after β,β′-iminodipropionitrile degradation of the cytoskeleton

1996 • 25 citations

The beaded form of myelinated nerve fibers

1994 • 24 citations

Ultrastructural localization of amyloid β/A4 protein precursor in the normal rat brain

1993 • 12 citations

Localization of Alzheimer Amyloid Beta Protein Precursor and Its Relation to Senile Plaque Amyloid

1994 • 5 citations