Osmotically-induced nerve taurine depletion and the compatible osmolyte hypothesis in experimental diabetic neuropathy in the rat

Calmodulin Plays a Pivotal Role in Cellular Regulation

1980 • 2,441 citations

Biochemistry and physiology of taurine and taurine derivatives.

1968 • 1,038 citations

Sorbitol, Phosphoinositides, and Sodium-Potassium-ATPase in the Pathogenesis of Diabetic Complications

1987 • 905 citations

The Sorbitol Pathway and the Complications of Diabetes

1973 • 750 citations

Effects of insulin and dietary myoinositol on impaired peripheral motor nerve conduction velocity in acute streptozotocin diabetes.

1975 • 471 citations

Protein phosphorylation in the brain

1983 • 428 citations

Predominant osmotically active organic solutes in rat and rabbit renal medullas.

1986 • 382 citations

Regeneration and Repair of Myelinated Fibers in Sural-Nerve Biopsy Specimens from Patients with Diabetic Neuropathy Treated with Sorbinil

1988 • 298 citations

Taurine—a Possible Neurotransmitter ?

1971 • 256 citations

Impaired rat sciatic nerve sodium-potassium adenosine triphosphatase in acute streptozocin diabetes and its correction by dietary myo-inositol supplementation.

1983 • 246 citations

A Possible Role for Taurine in Osmoregulation Within the Brain

1988 • 223 citations

The effect of sudden changes in ionic concentrations on the membrane potential of single muscle fibres

1960 • 214 citations

Taurine: its biological role and clinical implications.

1985 • 205 citations

Determination of monosaccharides as aldononitrile, O-methyloxime, alditol, and cyclitol acetate derivatives by gas chromatography

1984 • 204 citations

Induction of aldose reductase and sorbitol in renal inner medullary cells by elevated extracellular NaCl.

1987 • 173 citations

Oxygen Free Radical Effects in Sciatic Nerve in Experimental Diabetes

1991 • 161 citations

Sorbitol, osmoregulation, and the complications of diabetes.

1988 • 141 citations

Spontaneous Activity of Primary Afferent Neurons in Diabetic BB/Wistar Rats: A Possible Mechanism of Chronic Diabetic Neuropathic Pain

1985 • 137 citations

Taurine in Development

1988 • 134 citations

Reversible diabetic nerve dysfunction: Structural correlates to electrophysiological abnormalities

1985 • 129 citations

Taurine and hypotaurine inhibit light-induced lipid peroxidation and protect rod outer segment structure

1985 • 124 citations

Free and lipid inositol, sorbitol and sugars in sciatic nerve obtained post-mortem from diabetic patients and control subjects

1983 • 110 citations

Preventive effect of long-term aldose reductase inhibition (ponalrestat) on nerve conduction and sural nerve structure in the spontaneously diabetic Bio-Breeding rat.

1990 • 109 citations

NEURONAL AND GLIAL SYSTEMS FOR γ‐AMINOBUTYRIC ACID METABOLISM

1975 • 104 citations

Taurine behaves as an osmolyte in Madin-Darby canine kidney cells. Protection by polarized, regulated transport of taurine.

1991 • 102 citations

Effects of Taurine on Calcium Ion Uptake and Protein Phosphorylation in Rat Retinal Membrane Preparations

1985 • 101 citations

Osmoregulation by slow changes in aldose reductase and rapid changes in sorbitol flux

1988 • 98 citations

Aldose reductase in the BB rat: isolation, immunological identification and localization in the retina and peripheral nerve

1987 • 96 citations

Pathogenesis and prevention of diabetic neuropathy

1988 • 91 citations

Morphine induced alterations of γ-aminobutyric acid and taurine contents and l-glutamate decar☐ylase activity in rat spinal cord and thalamus: Possible correlates with analgesic action of morphine

1978 • 84 citations

A simple HPLC method for quantitating major organic solutes of renal medulla

1989 • 84 citations

Increased Renal Aldose Reductase Activity, Immunoreactivity, and mRNA in Streptozocin-Induced Diabetic Rats

1989 • 81 citations

Characterization and purification of a mammalian osmoregulatory protein, aldose reductase, induced in renal medullary cells by high extracellular NaCl.

1987 • 77 citations

Fine-structural localization of aldose reductase and ouabain-sensitive, K+-dependent p-nitro-phenylphosphatase in rat peripheral nerve

1991 • 65 citations

Predominant osmotically active organic solutes in rat and rabbit renal medullas. J. Biol. Chem. 261, 5872-5877

1986 • 65 citations

The biology of taurine. Methods and mechanisms.

1987 • 63 citations

Taurine transport by microvillous membrane vesicles and the perfused cotyledon of the human placenta

1990 • 58 citations

Nonosmotic Diabetic Cataracts

1990 • 58 citations

Aldose Reductase Expression in Human Diabetic Retina and Retinal Pigment Epithelium

1988 • 55 citations

Effect of Insulin and Statil on Aldose Reductase Expression in Diabetic Rats

1991 • 53 citations

From Heart to Hypothesis: A Mechanism for the Calcium Modulatory Actions of Taurine

1987 • 48 citations

Relative contribution of diet and biosynthesis to the taurine content of the adult rat.

1982 • 46 citations

Taurine transport by rabbit kidney brush-border membranes: Coupling to sodium, chloride, and the membrane potential

1988 • 44 citations

Neutrophil Aldose Reductase Activity and its Association with Established Diabetic Microvascular Complications

1991 • 42 citations

FUNCTIONAL ASPECTS AND PATHOGENETIC CONSIDERATIONS OF THE NEUROPATHY IN THE SPONTANEOUSLY DIABETIC BB‐WISTAR RAT

1981 • 42 citations

Neuronal discharge hypersynchrony and the intracranial water balance in relation to glutamic acid and taurine redistribution: migraine and epilepsy.

1990 • 27 citations

γ‐Aminobutyric Acid Greatly Increases the In Vivo Extracellular Taurine in the Rat Hippocampus

1985 • 27 citations

Neuromodulatory and trophic actions of taurine.

1990 • 17 citations

Uptake and release of taurine--an overview.

1990 • 12 citations

Diabetic Polyneuropathy

1987 • 11 citations

A possible role for taurine in analgesia.

1990 • 9 citations