Phenyl-N-tert-butylnitrone Demonstrates Broad-Spectrum Inhibition of Apoptosis-Associated Gene Expression in Endotoxin-Treated Rats

Opposing Effects of ERK and JNK-p38 MAP Kinases on Apoptosis

1995 • 5,334 citations

Requirement for Generation of H ₂ O ₂ for Platelet-Derived Growth Factor Signal Transduction

1995 • 2,505 citations

Antioxidant and redox regulation of gene transcription

1996 • 1,999 citations

Oxidants as Stimulators of Signal Transduction

1997 • 1,380 citations

Activation of Mitogen-activated Protein Kinase by H2O2

1996 • 1,202 citations

Oxidative damage to brain proteins, loss of glutamine synthetase activity, and production of free radicals during ischemia/reperfusion-induced injury to gerbil brain.

1990 • 787 citations

Apoptosis and increased generation of reactive oxygen species in Down's syndrome neurons in vitro

1995 • 741 citations

Human fibroblasts release reactive oxygen species in response to interleukin-1 or tumour necrosis factor-α

1989 • 660 citations

Reactive Oxygen Species Mediate Cytokine Activation of c-Jun NH2-terminal Kinases

1996 • 491 citations

Apoptosis Induced by Withdrawal of Trophic Factors Is Mediated by p38 Mitogen-activated Protein Kinase

1997 • 471 citations

Activation and Involvement of p38 Mitogen-activated Protein Kinase in Glutamate-induced Apoptosis in Rat Cerebellar Granule Cells

1997 • 413 citations

Phosphorylation of c-Jun Is Necessary for Apoptosis Induced by Survival Signal Withdrawal in Cerebellar Granule Neurons

1998 • 365 citations

Age-related Decline in Mitogen-activated Protein Kinase Activity in Epidermal Growth Factor-stimulated Rat Hepatocytes

1996 • 351 citations

Detection and identification of short-lived free radicals by an electron spin resonance trapping technique

1968 • 337 citations

Stimulation of “Stress-regulated” Mitogen-activated Protein Kinases (Stress-activated Protein Kinases/c-Jun N-terminal Kinases and p38-Mitogen-activated Protein Kinases) in Perfused Rat Hearts by Oxidative and Other Stresses

1998 • 320 citations

Fas- or Ceramide-induced Apoptosis Is Mediated by a Rac1-regulated Activation of Jun N-terminal Kinase/p38 Kinases and GADD153

1997 • 302 citations

Low levels of reactive oxygen species as modulators of cell function

1995 • 250 citations

CECAL LIGATION AND PUNCTURE (CLP) INDUCES APOPTOSIS IN THYMUS, SPLEEN, LUNG, AND GUT BY AN ENDOTOXIN AND TNF-INDEPENDENT PATHWAY

1997 • 207 citations

Delayed treatment with the spin trap α‐phenyl‐N‐tert‐butyl nitrone (PBN) reduces infarct size following transient middle cerebral artery occlusion in rats

1994 • 196 citations

Nitrone spin traps and a nitroxide antioxidant inhibit a common pathway of thymocyte apoptosis

1995 • 189 citations

Protection against oxidative damage to CNS by α-phenyl-tert-butyl nitrone (PBN) and other spin-trapping agents: A novel series of nonlipid free radical scavengers

1991 • 183 citations

Structure-Function Relationship of Lipoprotein Lipase-mediated Enhancement of Very Low Density Lipoprotein Binding and Catabolism by the Low Density Lipoprotein Receptor

1996 • 153 citations

Apoptosis Decision Cascades and Neuronal Degeneration in Alzheimer’s Disease

1998 • 146 citations

Programmed Cell Death in the Developing Nervous System

1996 • 120 citations

Interaction of α‐Phenyl‐N‐tert‐Butyl Nitrone and Alternative Electron Acceptors with Complex I Indicates a Substrate Reduction Site Upstream from the Rotenone Binding Site

1998 • 118 citations

Interleukin-1β Induction of Mitogen-activated Protein Kinases in Human Mesangial Cells

1997 • 116 citations

Spin Trapping Agent, Phenyl N-tertbutyl Nitrone (PBN) Inhibits Induction of Nitric Oxide Synthase in Endotoxin-Induced Shock in Mice

1995 • 87 citations

Chapter 13 Nitrone-Based Free Radical Traps as Neuroprotective Agents in Cerebral Ischaemia and Other Pathologies

1996 • 85 citations

Lipopolysaccharide induces apoptosis in a bovine endothelial cell line via a soluble CD14 dependent pathway

1998 • 79 citations

JNK (c-Jun NH2-terminal Kinase) Is a Target for Antioxidants in T Lymphocytes

1996 • 71 citations

Spin trap salvage from endotoxemia: the role of cytokine down-regulation.

1992 • 59 citations

Oxygen radicals in experimental shock

1992 • 50 citations

Inhibition by phenyl N-tert-butyl nitrone of early phase carcinogenesis in the livers of rats fed a choline-deficient, L-amino acid-defined diet.

1998 • 46 citations

Induction of the protooncogene c-fos and recovery of cytosolic adenosine triphosphate in reperfused liver after transient warm ischemia: effect of nitrone free-radical spin-trap agents.

1991 • 8 citations

Books-Received - the Behavior of Chemical Elements in Stars

1995 • 2 citations