Human acid beta-glucosidase: isolation and amino acid sequence of a peptide containing the catalytic site.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

Silver staining of proteins in polyacrylamide gels

1981 • 3,565 citations

[36] High-sensitivity sequencing with a gas-phase sequenator

1983 • 670 citations

The Metabolism of Glucocerebrosides

1965 • 276 citations

Gaucher Disease: A Century of Delineation and Research

1983 • 221 citations

Molecular cloning and nucleotide sequence of human glucocerebrosidase cDNA.

1985 • 209 citations

Isolation of β-galactosidase and β-glucosidase from brain

1966 • 149 citations

Enzyme replacement therapy in Gaucher's disease: large-scale purification of glucocerebrosidase suitable for human administration.

1977 • 133 citations

Mutations of glucocerebrosidase: discrimination of neurologic and non-neurologic phenotypes of Gaucher disease.

1982 • 121 citations

Mechanism of activation of glucocerebrosidase by CO-β-glucosidase (glucosidase activator protein)

1981 • 115 citations

[40] Glucosidases

1977 • 88 citations

Partial amino acid sequences around the essential carboxylate in the active sites of the intestinal sucrase-isomaltase complex.

1976 • 81 citations

The primary structure of staphylococcal protease

1978 • 77 citations

N-Hexyl-0-glucosyl sphingosine, an inhibitor of glucosyl ceramide, β-glucosidase

1973 • 77 citations

Isolation and structure of a tryptic glycopeptide from the active site of β-glucosidase A3 from Aspergillus wentii

1980 • 74 citations

Synthesis of a fluorescent derivative of glucosyl ceramide for the sensitive determination of glucocerebrosidase activity

1984 • 70 citations

Solubilization of glucocerebrosidase from human placenta and demonstration of a phospholipid requirement for its catalytic activity

1976 • 66 citations

Genetic heterogeneity in Gaucher disease: Physicokinetic and immunologic studies of the residual enzyme in cultured fibroblasts from non‐neuronopathic and neuronopathic patients

1985 • 65 citations

Affinity Labeling of the Active Sites in the Sucrase-Isomaltase Complex from Small Intestine

1974 • 59 citations

Preparation of psychosines (1‐O‐hexosyl sphingosine) from cerebrosides

1974 • 53 citations

Isolation and Amino Acid Sequence of a Hexadecapeptide from the Active Site of ß-Glucosidase A₃ from Aspergillus wentii

1974 • 50 citations

Human lysosomal β-glucosidase: Kinetic characterization of the catalytic, aglycon, and hydrophobic binding sites

1984 • 45 citations

Amino acid sequence at the active site of β-glucosidase a from bitter almonds

1978 • 44 citations

Gaucher disease types 1, 2, and 3: differential mutations of the acid beta-glucosidase active site identified with conduritol B epoxide derivatives and sphingosine.

1985 • 43 citations

Enzymic Differentiation of Neurologic and Nonneurologic Forms of Gaucher's Disease

1982 • 42 citations

A BASIC microcomputer program for plotting the secondary structure of proteins

1982 • 42 citations

Human lysosomal β-glucosidase: Purification by affinity chromatography

1984 • 30 citations

Purification of glucosylceramidase by affinity chromatography

1982 • 26 citations

Use of Activators and Inhibitors to Define the Properties of the Active Site of Normal and Gaucher Disease Lysosomal ß-Glucosidase

1985 • 19 citations