Human lysosomal β-glucosidase: Kinetic characterization of the catalytic, aglycon, and hydrophobic binding sites

A linear equation that describes the steady-state kinetics of enzymes and subcellular particles interacting with tightly bound inhibitors

1972 • 524 citations

The influence of bile salt structure on self-association in aqueous solutions.

1983 • 521 citations

Kinetic analysis of phospholipase A2 activity toward mixed micelles and its implications for the study of lipolytic enzymes

1975 • 278 citations

The Metabolism of Glucocerebrosides

1965 • 276 citations

Gaucher Disease: A Century of Delineation and Research

1983 • 221 citations

Practical enzymology of the sphingolipidoses

1977 • 183 citations

Isolation and Characterization of Glucocerebrosidase from Human Placental Tissue

1973 • 169 citations

Isolation of β-galactosidase and β-glucosidase from brain

1966 • 149 citations

The use of inhibitors in the study of glycosidases

1982 • 145 citations

Purification and properties of a heat-stable glucocerebrosidase activating factor from control and Gaucher spleen.

1977 • 118 citations

Mechanism of activation of glucocerebrosidase by CO-β-glucosidase (glucosidase activator protein)

1981 • 115 citations

Purification and characterization of a cytosolic broad specificity beta-glucosidase from human liver.

1981 • 115 citations

Kinetics of enzyme reactions with interaction between a substrate and a (metal) modifier

1969 • 99 citations

N-Hexyl-0-glucosyl sphingosine, an inhibitor of glucosyl ceramide, β-glucosidase

1973 • 77 citations

Synthesis of a fluorescent derivative of glucosyl ceramide for the sensitive determination of glucocerebrosidase activity

1984 • 70 citations

Solubilization of glucocerebrosidase from human placenta and demonstration of a phospholipid requirement for its catalytic activity

1976 • 66 citations

Active site directed inhibitors and mechanism of action of glycosidases

1973 • 59 citations

Deficiency of glucosylsphingosine: -Glucosidase in Gaucher disease

1973 • 47 citations

Enzymic Differentiation of Neurologic and Nonneurologic Forms of Gaucher's Disease

1982 • 42 citations

Assignment of the gene for acid beta-glucosidase to human chromosome 1.

1981 • 41 citations

Activation of membrane-bound glucosylceramide: beta-glucosidase in fibroblasts cultured from normal and glucosylceramidotic human skin.

1979 • 38 citations

Synthetic inhibitors of glucocerebroside β-glucosidase

1975 • 29 citations

Gaucher's Disease II. Studies on the Kinetics of β-Glucosidase and the Effects of Sodium Taurocholate in Normal and Gaucher Tissues

1980 • 24 citations

Regional assignment of the structural gene for human acid β-glucosidase to q42→qter on chromosome 1

1982 • 21 citations

Gaucher disease. III. Substrate specificity of glucocerebrosidase and the use of nonlabeled natural substrates for the investigation of patients.

1980 • 20 citations

Comparison of synthetic and natural glucosylceramides as substrate for glucosylceramidase assay

1982 • 18 citations

Hydrolytic and transglucosylation activities of a purified calf spleen β-glucosidase

1975 • 18 citations

Kinetics and protein subunit interactions of Escherichia coli phosphatidylserine decarboxylase in detergent solution

1981 • 11 citations

Comparison of rates of hydrolysis of N-oleoyl and N-stearoyl glucocerebroside in patients with gaucher's disease

1979 • 5 citations