Toll-like receptor 4 deficiency: Smaller infarcts, but nogain in function

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

1998 • 7,541 citations

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

1997 • 5,522 citations

Cutting Edge: Heat Shock Protein 60 Is a Putative Endogenous Ligand of the Toll-Like Receptor-4 Complex

2000 • 1,632 citations

Oligosaccharides of Hyaluronan Activate Dendritic Cells via Toll-like Receptor 4

2002 • 1,339 citations

The Extra Domain A of Fibronectin Activates Toll-like Receptor 4

2001 • 1,200 citations

Inflammatory Cytokines and Postmyocardial Infarction Remodeling

2004 • 988 citations

CCL2/Monocyte Chemoattractant Protein-1 Regulates Inflammatory Responses Critical to Healing Myocardial Infarcts

2005 • 656 citations

Reduced Myocardial Ischemia-Reperfusion Injury in Toll-Like Receptor 4-Deficient Mice

2004 • 603 citations

Endogenous tumor necrosis factor protects the adult cardiac myocyte against ischemic-induced apoptosis in a murine model of acute myocardial infarction

2000 • 423 citations

Cardiac cytokine expression is upregulated in the acute phase after myocardial infarction. Experimental studies in rats

2002 • 294 citations

Hemodynamic Regulation of Tumor Necrosis Factor-α Gene and Protein Expression in Adult Feline Myocardium

1997 • 284 citations

Endotoxin pretreatment increases endogenous myocardial catalase activity and decreases ischemia-reperfusion injury of isolated rat hearts.

1989 • 267 citations

In Vivo Evidence for a Role of Toll-Like Receptor 4 in the Development of Intimal Lesions

2002 • 235 citations

Toll-like receptor 4 mediates ischemia/reperfusion injury of the heart

2004 • 218 citations

In Vivo Expression of Proinflammatory Mediators in the Adult Heart after Endotoxin Administration: The Role of Toll‐Like Receptor–4

2001 • 212 citations

Demonstration of an early and a late phase of ischemic preconditioning in mice

1998 • 181 citations

The role of interleukin-6 in the failing heart.

2001 • 178 citations

Escherichia coliLPS-induced LV dysfunction: role of toll-like receptor-4 in the adult heart

2002 • 166 citations

A chronic mouse model of myocardial ischemia-reperfusion: essential in cytokine studies

2000 • 163 citations

Cytokine-induced nitric oxide production inhibits mitochondrial energy production and impairs contractile function in rat cardiac myocytes

2000 • 157 citations

Cellular Cardiomyoplasty Improves Survival After Myocardial Injury

2002 • 143 citations

Quantitative 3-Dimensional Echocardiography for Accurate and Rapid Cardiac Phenotype Characterization in Mice

2004 • 113 citations

TOLL-LIKE RECEPTOR 4, NITRIC OXIDE, AND MYOCARDIAL DEPRESSION IN ENDOTOXEMIA

2005 • 107 citations

Cellular Basis for the Acute Inhibitory Effects of IL-6 and TNF- on Excitation-contraction Coupling

1999 • 98 citations

Endotoxin and ischemic preconditioning: TNF-α concentration and myocardial infarct development in rabbits

1999 • 84 citations

In vivo assessment of absolute perfusion and intracapillary blood volume in the murine myocardium by spin labeling magnetic resonance imaging

2005 • 77 citations

Cardiac Inflammation and Innate Immunity in Septic Shock

2002 • 76 citations

MyD88 and NOS2 are essential for Toll-like receptor 4-mediated survival effect in cardiomyocytes

2006 • 70 citations

TNF? in ischemia/reperfusion injury and heart failure

2004 • 65 citations

Lipopolysaccharide Improves Cardiomyocyte Survival and Function after Serum Deprivation

2005 • 62 citations

Ischemic Preconditioning and Lipopolysaccharide Attenuate Nuclear Factor-.KAPPA.B Activation and Gene Expression of Inflammatory Cytokines in the Ischemia-Reperfused Rat Heart.

2001 • 54 citations

LPS induces late cardiac functional protection against ischemia independent of cardiac and circulating TNF-α

1997 • 41 citations

Endotoxin Induces a Second Window of Protection in the Rat Heart as Determined by Using p -Nitro-Blue Tetrazolium Staining, Cardiac Troponin T Release, and Histology

1999 • 38 citations

Post-ischemic cardiac chamber stiffness and coronary vasomotion: the role of edema and effects of dextran

1986 • 33 citations