Oxidative stress: Excited oxygen species and enzyme activity

Hydroperoxide metabolism in mammalian organs.

1979 • 5,821 citations

Free Radical Mechanisms in Tissue Injury

1988 • 1,585 citations

[48] Assay of glutathione, glutathione disulfide, and glutathione mixed disulfides in biological samples

1981 • 1,564 citations

Free-radical mechanisms in tissue injury

1984 • 1,518 citations

The Isoenzymes of Glutathione Transferase

1985 • 960 citations

The metabolism of menadione (2-methyl-1,4-naphthoquinone) by isolated hepatocytes. A study of the implications of oxidative stress in intact cells.

1982 • 893 citations

Oxidases and Related Redox Systems

1982 • 818 citations

A novel biologically active seleno-organic compound—1

1984 • 810 citations

Toxic drug effects associated with oxygen metabolism: Redox cycling and lipid peroxidation

1981 • 650 citations

Ethane Evolution: A New Index of Lipid Peroxidation

1974 • 449 citations

A novel biologically active seleno-organic compound—II

1984 • 418 citations

The relationship of biliary glutathione disulfide efflux and intracellular glutathione disulfide content in perfused rat liver.

1982 • 336 citations

Organ chemiluminescence: noninvasive assay for oxidative radical reactions.

1980 • 322 citations

Oxygen Radicals in Chemistry and Biology

1985 • 285 citations

Glutathione Peroxidase Brought into Focus

1982 • 267 citations

Clinical, Biochemical and Nutritional Aspects of Trace Elements

1983 • 266 citations

Enzymatic Basis of Detoxication

1981 • 244 citations

[26] Low-level chemiluminescence as an indicator of singlet molecular oxygen in biological systems

1984 • 231 citations

[59] Glutathione disulfide (GSSG) efflux from cells and tissues

1984 • 197 citations

Hepatic low-level chemiluminescence during redox cycling of menadione and the menadione-glutathione conjugate: Relation to glutathione and NAD(P)H:quinone reductase (DT-diaphorase) activity

1983 • 180 citations

Cytotoxicity from Coupled Redox Cycling of Autoxidizing Xenobiotics and Metals: A Selective Critical Review and Commentary on Work‐in‐Progress

1984 • 170 citations

Effect of ethanol on glutathione concentration in isolated hepatocytes

1980 • 164 citations

A novel biologically active selenoorganic compound—IV

1985 • 151 citations

Role of alcohol dehydrogenase activity and the acetaldehyde in ethanol- induced ethane and pentane production by isolated perfused rat liver

1982 • 146 citations

Free Radicals, Lipid Peroxidation and Cancer

1983 • 143 citations

Metabolic Basis of Detoxication

1982 • 142 citations

Monitoring lipid peroxidation by breath analysis: Endogenous hydrocarbons and their metabolic elimination

1980 • 141 citations

A novel biologically active seleno-organic compound—III

1984 • 140 citations

Halide dependence of the myeloperoxidase-mediated antimicrobial system of the polymorphonuclear leukocyte in the phenomenon of electronic excitation

1975 • 131 citations

Biological Basis of Detoxication

1983 • 130 citations

Chloroperoxidase. IX. Structure of compound I

1972 • 122 citations

Singlet oxygen production by chloroperoxidase-hydrogen peroxide-halide systems.

1984 • 117 citations

Ultraweak chemiluminescence: a sensitive assay for oxidative radical reactions.

1981 • 112 citations

Singlet Oxygen Formation Detected by Low-Level Chemiluminescence during Enzymatic Reduction of Prostaglandin G₂to H₂

1983 • 109 citations

Effects of 4-hydroxynonenal on isolated hepatocytes. Studies on chemiluminescence response, alkane production and glutathione status

1983 • 109 citations

Quinone-Induced Oxidative Injury to Cells and Tissues

1985 • 109 citations

CYTOTOXIC REACTIONS OF FREE RADICAL SPECIES OF OXYGEN*

1978 • 101 citations

Spectral evidence for the cytochrome P450 nature of prostacyclin synthetase

1981 • 100 citations

Evaluation of α-tocopherol antioxidant activity in microsomal lipid peroxidation as detected by low-level chemiluminescence

1984 • 96 citations

Low-Level Chemiluminescence of Isolated Hepatocytes

1981 • 93 citations

A Novel biologically active seleno-organic compound-I, glutathione peroxidase-like activity in vitro and antioxidant capacity of PZ51 (ebselen)

1984 • 93 citations

Low-Level Chemiluminescence of Biological Systems

1984 • 83 citations

BIOLOGICAL CHEMILUMINESCENCE

1983 • 79 citations

Organic Peroxy Free Radicals as Ultimate Agents in Oxygen Toxicity

1985 • 78 citations

Myeloperoxidase singlet molecular oxygen generation detected by direct infrared electronic emission

1984 • 61 citations

Antioxidant effect of diethyldithiocarbamate on microsomal lipid peroxidation assessed by low‐level chemiluminescence and alkane production

1983 • 60 citations

Oxidative Stress and Formation of Excited Species

1985 • 54 citations

Enzyme system generation of singlet (1.DELTA.g) molecular oxygen observed directly by 1.0-1.8-.mu. luminescence spectroscopy

1983 • 51 citations

The role of lipid peroxidation during chronic and acute exposure to ethanol as determined by pentane expiration in the rat

1981 • 49 citations

Protection against reactive oxygen species by NAD(P)H:quinone reductase induced by the dietary antioxidant butylated hydroxyanisole (BHA)

1984 • 47 citations

Paraquat-induced chemiluminescence of microsomal fractions

1983 • 46 citations

Biological Basis of Detoxication of Oxygen Free Radicals

1983 • 44 citations

Oxene Donors Yield Low‐Level Chemiluminescence with Microsomes and Isolated Cytochrome P‐450

1983 • 44 citations

Singlet oxygen production by lactoperoxidase: Halide dependence and quantitation of yield

1984 • 43 citations

Superoxide Dismutases: Detoxication of a Free Radical

1980 • 41 citations

Biological Oxidations

1983 • 41 citations

[37] Assay of ethane and pentane from isolated organs and cells

1984 • 39 citations

Cellular redox changes and response to drugs and toxic agents

1983 • 38 citations

Interactions of (+)-Cyanidanol-3 with Free Radical Generating Systems

2015 • 37 citations

The critical steady-state hypoxic conditions in carbon tetrachloride-induced lipid peroxidation in rat liver microsomes

1984 • 36 citations

The Role of Ethanol Metabolites in Hepatic Lipid Peroxidation

1977 • 35 citations

Effect of (+)-Cyanidanol-3 on the Changes in Liver Glutathione Content and Lipoperoxidation Induced by Acute Ethanol Administration in the Rat

1981 • 35 citations

Halothane-induced Lipid Peroxidation and Glucose-6-phosphatase Inactivation in Microsomes under Hypoxic Conditions

1985 • 34 citations

Singlet Oxygen in Biological Processes

1982 • 21 citations

Ethane Release during Metabolism of Aldehydes and Monoamines in Perfused Rat Liver

1983 • 20 citations

Inhibition of ethanol- and aldehyde-induced release of ethane from isolated perfused rat liver by pargyline and disulfiram

1983 • 20 citations

Active oxygen metabolites and their action in the hepatocyte. Studies on chemiluminescence responses and alkane production.

1982 • 16 citations

Metabolism of Organic Hydroperoxides

1982 • 16 citations

Oxygen Radicals and Hydroperoxides in Mammalian Organs: Aspects of Redox Cycling and Hydrogen Peroxide Metabolism

1983 • 15 citations

Generation of low-level chemiluminescence during the metabolism of 1-naphthol by rat liver microsomes

1984 • 6 citations

Se and Non-Se Glutathione Peroxidases: Enzymology and Cell Physiology

1982 • 2 citations

ALKANE EVOLUTION AND CHEMILUMINESCENCE INDUCED BY ALDEHYDIC PRODUCTS OF LIPID PEROXIDATION

1984 • 2 citations

LOW-LEVEL CHEMILUMINESCENCE, ALKANE PRODUCTION AND GLUTATHIONE DEPLETION IN ISOLATED HEPATOCYTES CAUSED BY A DIFFUSIBLE PRODUCT OF LIPID PEROXIDATION, 4-HYDROXYNONENAL

1984 • 1 citations