Protective effects of the TNF-ceramide pathway against glutamate neurotoxicity on cultured mesencephalic neurons

An Essential Role for NF-κB in Preventing TNF-α-Induced Cell Death

1996 • 3,094 citations

TNF- and Cancer Therapy-Induced Apoptosis: Potentiation by Inhibition of NF-κB

1996 • 2,665 citations

Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate

1996 • 1,493 citations

Tumor necrosis factor-α (TNF-α) increases both in the brain and in the cerebrospinal fluid from parkinsonian patients

1994 • 923 citations

Nuclear translocation of NF-κB is increased in dopaminergic neurons of patients with Parkinson disease

1997 • 676 citations

Tumor necrosis factors protect neurons against metabolic-excitotoxic insults and promote maintenance of calcium homeostasis

1994 • 672 citations

Immunocytochemical analysis of tumor necrosis factor and its receptors in Parkinson's disease

1994 • 576 citations

Activation of NF-?B protects hippocampal neurons against oxidative stress-induced apoptosis: Evidence for induction of manganese superoxide dismutase and suppression of peroxynitrite production and protein tyrosine nitration

1997 • 572 citations

Involvement of Sphingosine 1-Phosphate in Nerve Growth Factor-Mediated Neuronal Survival and Differentiation

1997 • 278 citations

Ceramide Protects Hippocampal Neurons Against Excitotoxic and Oxidative Insults, and Amyloid β‐Peptide Toxicity

1996 • 229 citations

Induction of neuroprotective κB-dependent transcription by secreted forms of the Alzheimer's β-amyloid precursor

1996 • 192 citations

Ceramide Induces Apoptosis in Cultured Mesencephalic Neurons

1996 • 191 citations

Mitochondrial Free Radical Signal in Ceramide‐Dependent Apoptosis: A Putative Mechanism for Neuronal Death in Parkinson's Disease

1997 • 186 citations

Inhibition of nuclear factor kappa B (NF?B) activity induces nerve growth factor-resistant apoptosis in PC12 cells

1997 • 177 citations

Janus faces of NF-κB: Neurodestruction versus neuroprotection

1997 • 163 citations

N,N-Dimethylsphingosine Inhibition of Sphingosine Kinase and Sphingosine 1-Phosphate Activity in Human Platelets

1996 • 162 citations

AMPA and NMDA glutamate receptor subunits in midbrain dopaminergic neurons in the squirrel monkey: an immunohistochemical and in situ hybridization study.

1997 • 103 citations

AMPA and NMDA Glutamate Receptor Subunits in Midbrain Dopaminergic Neurons in the Squirrel Monkey: An Immunohistochemical andIn SituHybridization Study

1997 • 81 citations

Tumor necrosis factor enhancement of transient outward potassium currents in cultured rat cortical neurons

1997 • 68 citations

Glutamate neurotoxicity in mesencephalic dopaminergic neurons in culture

1993 • 57 citations

Marked diversity in the action of growth factors on N-methyl-d-rmaspartate-induced neuronal degeneration

1996 • 44 citations

Brain TNF: Damage limitation or damaged reputation?

1996 • 41 citations