The role of leptin in human growth and puberty

Positional cloning of the mouse obese gene and its human homologue

1994 • 12,975 citations

Serum Immunoreactive-Leptin Concentrations in Normal-Weight and Obese Humans

1996 • 6,254 citations

Recombinant Mouse OB Protein: Evidence for a Peripheral Signal Linking Adiposity and Central Neural Networks

1995 • 3,302 citations

Congenital leptin deficiency is associated with severe early-onset obesity in humans

1997 • 2,900 citations

A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction

1998 • 2,333 citations

Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin

1996 • 1,505 citations

A leptin missense mutation associated with hypogonadism and morbid obesity

1998 • 1,187 citations

Critical periods in childhood for the development of obesity

1994 • 1,077 citations

Physiological response to long-term peripheral and central leptin infusion in lean and obese mice

1997 • 1,043 citations

Early Onset of Reproductive Function in Normal Female Mice Treated with Leptin

1997 • 844 citations

Plasma Leptin Levels in Healthy Children and Adolescents: Dependence on Body Mass Index, Body Fat Mass, Gender, Pubertal Stage, and Testosterone*

1997 • 648 citations

Programming by Early Nutrition: An Experimental Approach

1998 • 624 citations

A Longitudinal Assessment of Hormonal and Physical Alterations during Normal Puberty in Boys. V. Rising Leptin Levels May Signal the Onset of Puberty¹

1997 • 435 citations

Plasma Leptin Levels in Healthy Children and Adolescents: Dependence on Body Mass Index, Body Fat Mass, Gender, Pubertal Stage, and Testosterone

1997 • 379 citations

A Longitudinal Assessment of Hormonal and Physical Alterations during Normal Puberty in Boys. V. Rising Leptin Levels May Signal the Onset of Puberty

1997 • 298 citations

Association of the INS VNTR with size at birth

1998 • 260 citations

Intraventricular Leptin Reduces Food Intake and Body Weight of Lean Rats but Not Obese Zucker Rats

1996 • 257 citations

Shifting linear growth during infancy: Illustration of genetic factors in growth from fetal life through infancy

1976 • 256 citations

Relatively low plasma leptin concentrations precede weight gain in Pima Indians

1997 • 243 citations

Longitudinal Study of Leptin Concentrations during Puberty: Sex Differences and Relationship to Changes in Body Composition1

1999 • 237 citations

Cord Blood Leptin Is Associated with Size at Birth and Predicts Infancy Weight Gain in Humans

1999 • 233 citations

Leptin increases energy expenditure and selectively promotes fat metabolism in ob/ob mice

1997 • 203 citations

Longitudinal Study of Leptin Concentrations during Puberty: Sex Differences and Relationship to Changes in Body Composition

1999 • 132 citations

Height, Weight and Age at Menarche and the "Critical Weight" Hypothesis

1971 • 130 citations

THE INFANT'S SELF-REGULATION OF FOOD INTAKE AND WEIGHT GAIN

1975 • 128 citations

Increased Plasma Leptin Levels Are Associated With Fat Accumulation in Japanese Americans

1998 • 91 citations

Weight and age at menarche.

1989 • 89 citations

Growth as a Target-Seeking Function

1986 • 69 citations

Early growth predicts timing of puberty in boys: Results of a 14-year nutrition and growth study

1986 • 54 citations

Increased Leptin Resistance as Rats Grow to Maturity

1998 • 43 citations

Leptin concentrations do not predict weight gain: The Mexico City Diabetes Study

1998 • 41 citations

Do Leptin Levels Predict Weight Gain?-A 5-Year Follow-Up Study in Mauritius

1998 • 36 citations