Cerebral organoids model human brain development and microcephaly

Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors

2006 • 24,853 citations

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

2009 • 6,026 citations

Generation of germline-competent induced pluripotent stem cells

2007 • 4,163 citations

Organoid Models and Applications in Biomedical Research

2015 • 3,370 citations

The cell biology of neurogenesis

2005 • 1,979 citations

A ROCK inhibitor permits survival of dissociated human embryonic stem cells

2007 • 1,958 citations

Self-organizing optic-cup morphogenesis in three-dimensional culture

2011 • 1,815 citations

Self-Organized Formation of Polarized Cortical Tissues from ESCs and Its Active Manipulation by Extrinsic Signals

2008 • 1,332 citations

Self-Formation of Optic Cups and Storable Stratified Neural Retina from Human ESCs

2012 • 1,309 citations

Neurogenic radial glia in the outer subventricular zone of human neocortex

2010 • 1,246 citations

Development and Evolution of the Human Neocortex

2011 • 1,219 citations

Electroporation and RNA interference in the rodent retina in vivo and in vitro

2003 • 987 citations

MicroRNA-mediated conversion of human fibroblasts to neurons

2011 • 911 citations

Tbr1 Regulates Differentiation of the Preplate and Layer 6

2001 • 830 citations

Cleavage orientation and the asymmetric inheritance of notchl immunoreactivity in mammalian neurogenesis

1995 • 764 citations

OSVZ progenitors of human and ferret neocortex are epithelial-like and expand by integrin signaling

2010 • 756 citations

An Essential Switch in Subunit Composition of a Chromatin Remodeling Complex during Neural Development

2007 • 707 citations

Unique Morphological Features of the Proliferative Zones and Postmitotic Compartments of the Neural Epithelium Giving Rise to Striate and Extrastriate Cortex in the Monkey

2002 • 644 citations

An intrinsic mechanism of corticogenesis from embryonic stem cells

2008 • 604 citations

A centrosomal mechanism involving CDK5RAP2 and CENPJ controls brain size

2005 • 556 citations

Modeling human cortical development in vitro using induced pluripotent stem cells

2012 • 498 citations

Neuroepithelial progenitors undergo LGN-dependent planar divisions to maintain self-renewability during mammalian neurogenesis

2007 • 488 citations

Self-formation of functional adenohypophysis in three-dimensional culture

2011 • 470 citations

Oblique Radial Glial Divisions in the Developing Mouse Neocortex Induce Self-Renewing Progenitors outside the Germinal Zone That Resemble Primate Outer Subventricular Zone Progenitors

2011 • 428 citations

Retinoic Acid from the Meninges Regulates Cortical Neuron Generation

2009 • 396 citations

Nucleokinesis in Neuronal Migration

2005 • 347 citations

Growth and targeting of subplate axons and establishment of major cortical pathways [published erratum appears in J Neurosci 1993 Mar;13(3):following table of contents]

1992 • 342 citations

Tbr1 regulates regional and laminar identity of postmitotic neurons in developing neocortex

2010 • 306 citations

Cajal—Retzius cells, Reelin, and the formation of layers

1998 • 278 citations

Neuroepithelial Stem Cell Proliferation Requires LIS1 for Precise Spindle Orientation and Symmetric Division

2008 • 267 citations

Contributions of cortical subventricular zone to the development of the human cerebral cortex

2005 • 261 citations

Cdk5rap2 regulates centrosome function and chromosome segregation in neuronal progenitors

2010 • 257 citations

Cortical progenitor expansion, self-renewal and neurogenesis—a polarized perspective

2010 • 253 citations

MCPH1 regulates the neuroprogenitor division mode by coupling the centrosomal cycle with mitotic entry through the Chk1–Cdc25 pathway

2011 • 223 citations

CEP152 is a genome maintenance protein disrupted in Seckel syndrome

2010 • 222 citations

The Functional Microarchitecture of the Mouse Barrel Cortex

2007 • 220 citations

Proliferative characteristics of the ependymal layer during the early development of the mouse neocortex: a pilot study based on recording the number, location and plane of cleavage of mitotic figures.

1973 • 203 citations

Mitotic spindle orientation predicts outer radial glial cell generation in human neocortex

2013 • 202 citations

Mapping the human brain: past, present, and future

1995 • 194 citations

Mutations in Centrosomal Protein CEP152 in Primary Microcephaly Families Linked to MCPH4

2010 • 190 citations

Mutations in mouse Aspm (abnormal spindle-like microcephaly associated) cause not only microcephaly but also major defects in the germline

2010 • 188 citations

What primary microcephaly can tell us about brain growth

2006 • 177 citations

Subregional Specification of Embryonic Stem Cell-Derived Ventral Telencephalic Tissues by Timed and Combinatory Treatment with Extrinsic Signals

2011 • 166 citations

Mouse Inscuteable Induces Apical-Basal Spindle Orientation to Facilitate Intermediate Progenitor Generation in the Developing Neocortex

2011 • 160 citations

Novel CENPJ mutation causes Seckel syndrome

2010 • 157 citations

CDK5RAP2 Regulates Centriole Engagement and Cohesion in Mice

2010 • 153 citations

Ontogeny-recapitulating generation and tissue integration of ES cell–derived Purkinje cells

2010 • 151 citations

Self-formation of layered neural structures in three-dimensional culture of ES cells

2012 • 150 citations

Cdk5rap2 exposes the centrosomal root of microcephaly syndromes

2011 • 121 citations

Making sense of the multiple MAP-2 transcripts and their role in the neuron

1998 • 88 citations

Directed Differentiation of Neural-stem cells and Subtype-Specific Neurons from hESCs

2010 • 78 citations

Further tales of the midline

2010 • 78 citations

A novel nonsense CDK5RAP2 mutation in a Somali child with primary microcephaly and sensorineural hearing loss

2012 • 39 citations

Cell biological regulation of division fate in vertebrate neuroepithelial cells

2011 • 36 citations

Culture of Mouse Embryonic Stem Cells

2008 • 36 citations

Differentiation of Neuroepithelia from Human Embryonic Stem Cells

2009 • 30 citations

Quantitative studies of mitoses in fetal rat brain: orientations of the spindles

1987 • 19 citations