Electroporation and RNA interference in the rodent retina in vivo and in vitro

Efficient selection for high-expression transfectants with a novel eukaryotic vector

1991 • 5,120 citations

A System for Stable Expression of Short Interfering RNAs in Mammalian Cells

2002 • 4,334 citations

Germline Transmission and Tissue-Specific Expression of Transgenes Delivered by Lentiviral Vectors

2002 • 2,019 citations

Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells

2002 • 1,526 citations

A common progenitor for neurons and glia persists in rat retina late in development

1987 • 1,395 citations

A DNA vector-based RNAi technology to suppress gene expression in mammalian cells

2002 • 1,117 citations

RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells

2002 • 1,037 citations

Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells

2002 • 965 citations

Crx, a Novel otx-like Homeobox Gene, Shows Photoreceptor-Specific Expression and Regulates Photoreceptor Differentiation

1997 • 882 citations

Lineage analysis in the vertebrate nervous system by retrovirus-mediated gene transfer.

1987 • 881 citations

Nrl is required for rod photoreceptor development

2001 • 872 citations

Effective expression of small interfering RNA in human cells

2002 • 827 citations

Efficient Gene Transfer into the Embryonic Mouse Brain Using in Vivo Electroporation

2001 • 740 citations

U6 promoter–driven siRNAs with four uridine 3′ overhangs efficiently suppress targeted gene expression in mammalian cells

2002 • 715 citations

The Rx homeobox gene is essential for vertebrate eye development

1997 • 699 citations

Crx, a Novel Otx-like Paired-Homeodomain Protein, Binds to and Transactivates Photoreceptor Cell-Specific Genes

1997 • 697 citations

Efficient in utero gene transfer system to the developing mouse brain using electroporation: visualization of neuronal migration in the developing cortex

2001 • 665 citations

Lineage-independent determination of cell type in the embryonic mouse retina

1990 • 656 citations

Cone-Rod Dystrophy Due to Mutations in a Novel Photoreceptor-Specific Homeobox Gene () Essential for Maintenance of the Photoreceptor

1997 • 542 citations

rax, Hes1, and notch1 Promote the Formation of Müller Glia by Postnatal Retinal Progenitor Cells

2000 • 519 citations

Retinopathy and attenuated circadian entrainment in Crx-deficient mice

1999 • 512 citations

STAT5 as a molecular regulator of proliferation, differentiation and apoptosis in hematopoietic cells

1999 • 503 citations

Stable and efficient gene transfer into the retina using an HIV-based lentiviral vector

1997 • 499 citations

Efficient photoreceptor-targeted gene expression in vivo by recombinant adeno-associated virus

1997 • 399 citations

Roles of the Basic Helix-Loop-Helix Genes Hes1 and Hes5 in Expansion of Neural Stem Cells of the Developing Brain

2001 • 393 citations

rax , a novel paired-type homeobox gene, shows expression in the anterior neural fold and developing retina

1997 • 346 citations

A conserved retina-specific gene encodes a basic motif/leucine zipper domain.

1992 • 308 citations

Comprehensive Analysis of Photoreceptor Gene Expression and the Identification of Candidate Retinal Disease Genes

2001 • 308 citations

The Expression and Function ofNotchPathway Genes in the Developing Rat Eye

1997 • 287 citations

Use of the human elongation factor 1α promoter as a versatile and efficient expression system

1990 • 273 citations

Microarray analysis of the transcriptional network controlled by the photoreceptor homeobox gene Crx

2000 • 271 citations

Polyglutamine-Expanded Ataxin-7 Antagonizes CRX Function and Induces Cone-Rod Dystrophy in a Mouse Model of SCA7

2001 • 260 citations

Five Members of a Novel Ca2+-binding Protein (CABP) Subfamily with Similarity to Calmodulin

2000 • 258 citations

Math3andNeuroDregulate amacrine cell fate specification in the retina

2002 • 258 citations

Roles of homeobox and >bHLH genes in specification of a retinal cell type

2001 • 235 citations

The cytomegalovirus enhancer: a pan-active control element in transgenic mice.

1990 • 211 citations

The Human Ubiquitin C Promoter Directs High Ubiquitous Expression of Transgenes in Mice

1996 • 203 citations

Immunocytochemical description of five bipolar cell types of the mouse retina

2002 • 200 citations

Unusual topography of bovine rhodopsin promoter-IacZ fusion gene expression in transgenic mouse retinas

1991 • 197 citations

Sparking New Frontiers: Using in Vivo Electroporation for Genetic Manipulations

2001 • 171 citations

Two Phases of Rod Photoreceptor Differentiation during Rat Retinal Development

1998 • 147 citations

Multiple Phosphorylated Isoforms of NRL Are Expressed in Rod Photoreceptors

2001 • 119 citations

Monoclonal antibodies to rhodopsin and other proteins of rod outer segments

1988 • 111 citations

Gene transfer into retinal ganglion cells by in vivo electroporation: a new approach

2002 • 86 citations

The Cytomegalovirus Enhancer: a Pan-Active Control Element in Transgenic Mice

1990 • 66 citations

Mouse eye gene microarrays for investigating ocular development and disease

2002 • 48 citations

Molecular characterization of the mouse gene encoding cellular retinaldehyde-binding protein.

1998 • 13 citations