Niche-Independent Symmetrical Self-Renewal of a Mammalian Tissue Stem Cell

Generation of Neurons and Astrocytes from Isolated Cells of the Adult Mammalian Central Nervous System

1992 • 5,296 citations

Subventricular Zone Astrocytes Are Neural Stem Cells in the Adult Mammalian Brain

1999 • 3,822 citations

The relationship between the spleen colony-forming cell and the haemopoietic stem cell.

1978 • 2,290 citations

Optimized survival of hippocampal neurons in B27‐supplemented neurobasal™, a new serum‐free medium combination

1993 • 2,272 citations

Cortical neurons arise in symmetric and asymmetric division zones and migrate through specific phases

2004 • 2,120 citations

BMP Induction of Id Proteins Suppresses Differentiation and Sustains Embryonic Stem Cell Self-Renewal in Collaboration with STAT3

2003 • 2,079 citations

The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium

1985 • 1,983 citations

Neurons derived from radial glial cells establish radial units in neocortex

2001 • 1,932 citations

Stem cells: attributes, cycles, spirals, pitfalls and uncertainties. Lessons for and from the crypt

1990 • 1,793 citations

Out of Eden: Stem Cells and Their Niches

2000 • 1,769 citations

Endothelial Cells Stimulate Self-Renewal and Expand Neurogenesis of Neural Stem Cells

2004 • 1,498 citations

Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture

2003 • 1,497 citations

The development of neural stem cells

2001 • 1,474 citations

Stem cells find their niche

2001 • 1,428 citations

Astroglia induce neurogenesis from adult neural stem cells

2002 • 1,422 citations

Neural stem cells in the adult mammalian forebrain: A relatively quiescent subpopulation of subependymal cells

1994 • 1,400 citations

Three clonal types of keratinocyte with different capacities for multiplication.

1987 • 1,271 citations

Unique astrocyte ribbon in adult human brain contains neural stem cells but lacks chain migration

2004 • 1,261 citations

Multipotent CNS Stem Cells Are Present in the Adult Mammalian Spinal Cord and Ventricular Neuroaxis

1996 • 1,209 citations

Embryonic Stem Cells Express Neuronal Properties in Vitro

1995 • 1,173 citations

Single factors direct the differentiation of stem cells from the fetal and adult central nervous system.

1996 • 1,164 citations

Isolation of radial glial cells by fluorescent-activated cell sorting reveals a neuronal lineage

2000 • 1,108 citations

The Adult Rat Hippocampus Contains Primordial Neural Stem Cells

1997 • 1,080 citations

Noggin Antagonizes BMP Signaling to Create a Niche for Adult Neurogenesis

2000 • 1,064 citations

EGF Converts Transit-Amplifying Neurogenic Precursors in the Adult Brain into Multipotent Stem Cells

2002 • 1,030 citations

Embryonic Stem Cell-Derived Glial Precursors: A Source of Myelinating Transplants

1999 • 981 citations

A unified hypothesis on the lineage of neural stem cells

2001 • 976 citations

Timing of CNS Cell Generation

2000 • 825 citations

Radial glia give rise to adult neural stem cells in the subventricular zone

2004 • 810 citations

Development of neuronal precursor cells and functional postmitotic neurons from embryonic stem cells in vitro

1996 • 775 citations

Cleavage orientation and the asymmetric inheritance of notchl immunoreactivity in mammalian neurogenesis

1995 • 764 citations

Direct Neural Fate Specification from Embryonic Stem Cells

2001 • 754 citations

Characterization of CNS Precursor Subtypes and Radial Glia

2001 • 739 citations

Proliferation and differentiation of neuronal stem cells regulated by nerve growth factor

1990 • 720 citations

The glial identity of neural stem cells

2003 • 710 citations

A niche for adult neural stem cells

2003 • 612 citations

A culture system using human foreskin fibroblasts as feeder cells allows production of human embryonic stem cells

2003 • 501 citations

A role for SOX1 in neural determination

1998 • 470 citations

Generation of purified neural precursors from embryonic stem cells by lineage selection

1998 • 463 citations

Differentiation of mouse embryonic stem cells into a defined neuronal lineage

2004 • 449 citations

Kinetics and selectivity of a low‐voltage‐activated calcium current in chick and rat sensory neurones.

1987 • 420 citations

Division and differentiation of isolated CNS blast cells in microculture

1989 • 404 citations

Hematopoietic competence is a rare property of neural stem cells that may depend on genetic and epigenetic alterations

2002 • 396 citations

Establishment and characterization of multipotent neural cell lines using retrovirus vector‐mediated oncogene transfer

1990 • 375 citations

Radial glia: multi-purpose cells for vertebrate brain development

2002 • 373 citations

Asymmetric Numb distribution is critical for asymmetric cell division of mouse cerebral cortical stem cells and neuroblasts

2002 • 352 citations

Neural stem cell heterogeneity demonstrated by molecular phenotyping of clonal neurospheres

2002 • 337 citations

Immortalization of precursor cells from the mammalian CNS

1988 • 328 citations

Defined Conditions for Neural Commitment and Differentiation

2003 • 321 citations

Deregulation of Dorsoventral Patterning by FGF Confers Trilineage Differentiation Capacity on CNS Stem Cells In Vitro

2003 • 313 citations

In vitro -generated neural precursors participate in mammalian brain development

1997 • 313 citations

Generation of an environmental niche for neural stem cell development by the extracellular matrix molecule tenascin C

2004 • 308 citations

Neural stem cell therapy for neurological diseases: dreams and reality

2002 • 290 citations

Elusive radial glial cells: Historical and evolutionary perspective

2003 • 271 citations

Regionalization and fate specification in neurospheres: the role of Olig2 and Pax6

2004 • 268 citations

Screening for mammalian neural genes via fluorescence-activated cell sorter purification of neural precursors from Sox1 - gfp knock-in mice

2003 • 241 citations

Neuregulin 1–erbB2 signaling is required for the establishment of radial glia and their transformation into astrocytes in cerebral cortex

2003 • 201 citations

Asymmetric Distribution of EGFR Receptor during Mitosis Generates Diverse CNS Progenitor Cells

2005 • 200 citations

Migration patterns and phenotypic differentiation of long-term expanded human neural progenitor cells after transplantation into the adult rat brain

2002 • 161 citations

Normal timing of oligodendrocyte development from genetically engineered,lineage-selectable mouse ES cells

2002 • 136 citations

Emx2regulates the proliferation of stem cells of the adult mammalian central nervous system

2002 • 131 citations

Incorporation and Glial Differentiation of Mouse EGF-Responsive Neural Progenitor Cells after Transplantation into the Embryonic Rat Brain

1998 • 129 citations

Emx2 Promotes Symmetric Cell Divisions and a Multipotential Fate in Precursors from the Cerebral Cortex

2001 • 123 citations

Large-Scale Sources of Neural Stem Cells

2002 • 122 citations

Genesis of embryonic stem cells

2003 • 115 citations

Akt-1 Expression Level Regulates CNS Precursors

2004 • 114 citations

Radial ‘glial’ progenitors: neurogenesis and signaling

2005 • 102 citations

Generation of Functional Radial Glial Cells by Embryonic and Adult Forebrain Neural Stem Cells

2003 • 92 citations

Neural differentiation of mouse embryonic stem cells

2003 • 89 citations

Differentiation of radial glia‐like cells from embryonic stem cells

2003 • 68 citations

Basal ganglia precursors found in aggregates following embryonic transplantation adopt a striatal phenotype in heterotopic locations

1998 • 29 citations

Accuracy of Pressure-Flow Estimates of Velopharyngeal Orifice Size in an Analog Model and Human Subjects

1988 • 12 citations

Astrocytic nature of adult neural stem cells in vivo

2004 • 1 citations