Emx2 Promotes Symmetric Cell Divisions and a Multipotential Fate in Precursors from the Cerebral Cortex

Generation of Neurons and Astrocytes from Isolated Cells of the Adult Mammalian Central Nervous System

1992 • 5,296 citations

Production of high-titer helper-free retroviruses by transient transfection.

1993 • 2,280 citations

Neurons derived from radial glial cells establish radial units in neocortex

2001 • 1,932 citations

Out of Eden: Stem Cells and Their Niches

2000 • 1,769 citations

Localization of the glial fibrillary acidic protein in astrocytes by immunofluorescence

1972 • 1,456 citations

Pax-6, a murine paired box gene, is expressed in the developing CNS

1991 • 1,226 citations

Single factors direct the differentiation of stem cells from the fetal and adult central nervous system.

1996 • 1,164 citations

Isolation of radial glial cells by fluorescent-activated cell sorting reveals a neuronal lineage

2000 • 1,108 citations

A small step for the cell, a giant leap for mankind: a hypothesis of neocortical expansion during evolution

1995 • 1,000 citations

Integration of murine leukemia virus DNA depends on mitosis.

1993 • 931 citations

Lineage analysis in the vertebrate nervous system by retrovirus-mediated gene transfer.

1987 • 881 citations

Timing of CNS Cell Generation

2000 • 825 citations

Cleavage orientation and the asymmetric inheritance of notchl immunoreactivity in mammalian neurogenesis

1995 • 764 citations

Bromodeoxyuridine immunohistochemical determination of the lengths of the cell cycle and the DNA-synthetic phase for an anatomically defined population

1989 • 746 citations

Characterization of CNS Precursor Subtypes and Radial Glia

2001 • 739 citations

Radial Glial Identity Is Promoted by Notch1 Signaling in the Murine Forebrain

2000 • 716 citations

Transient Notch Activation Initiates an Irreversible Switch from Neurogenesis to Gliogenesis by Neural Crest Stem Cells

2000 • 715 citations

Pax6 Controls Radial Glia Differentiation in the Cerebral Cortex

1998 • 647 citations

Widespread Dispersion of Neuronal Clones Across Functional Regions of the Cerebral Cortex

1992 • 610 citations

The expression and posttranslational modification of a neuron‐specific β‐tubulin isotype during chick embryogenesis

1990 • 589 citations

Cell lineage in the cerebral cortex of the mouse studied in vivo and in vitro with a Recombinant Retrovirus

1988 • 569 citations

Regulation of Area Identity in the Mammalian Neocortex by Emx2 and Pax6

2000 • 564 citations

Proliferation and differentiation of rat neuroepithelial precursor cells in vivo

1988 • 563 citations

rax, Hes1, and notch1 Promote the Formation of Müller Glia by Postnatal Retinal Progenitor Cells

2000 • 519 citations

Two vertebrate homeobox genes related to the Drosophila empty spiracles gene are expressed in the embryonic cerebral cortex.

1992 • 472 citations

Multiple and novel specificities of monoclonal antibodies O1, O4, and R‐mAb used in the analysis of oligodendrocyte development

1989 • 422 citations

Cell lineage in the rat cerebral cortex: a study using retroviral-mediated gene transfer

1988 • 421 citations

Vertebrate retinal ganglion cells are selected from competent progenitors by the action of Notch

1995 • 409 citations

Changes in cerebral cortex size are governed by fibroblast growth factor during embryogenesis

1999 • 397 citations

Persistent expression of helix-loop-helix factor HES-1 prevents mammalian neural differentiation in the central nervous system.

1994 • 395 citations

Emx1andEmx2functions in development of dorsal telencephalon

1997 • 365 citations

The Encephalomyocarditis Virus Internal Ribosome Entry Site Allows Efficient Coexpression of Two Genes from a Recombinant Provirus in Cultured Cells and in Embryos

1991 • 333 citations

Cell cycle parameters and patterns of nuclear movement in the neocortical proliferative zone of the fetal mouse

1993 • 324 citations

Sequence of Neuron Origin and Neocortical Laminar Fate: Relation to Cell Cycle of Origin in the Developing Murine Cerebral Wall

1999 • 320 citations

The neural crest cell lineage problem: Neuropoiesis?

1989 • 315 citations

The bHLH GeneHes1as a Repressor of the Neuronal Commitment of CNS Stem Cells

2000 • 311 citations

Xotch inhibits cell differentiation in the xenopus retina

1995 • 293 citations

The generation of neurons and oligodendrocytes from a common precursor cell

1991 • 274 citations

Glial cell fate specification modulated by the bHLH gene Hes5in mouse retina

2000 • 269 citations

Clonal dispersion in proliferative layers of developing cerebral cortex

1993 • 262 citations

Expression and embryonic function of empty spiracles: a Drosophila homeo box gene with two patterning functions on the anterior-posterior axis of the embryo.

1989 • 257 citations

Area identity shifts in the early cerebral cortex of Emx2−/− mutant mice

2000 • 251 citations

Intrinsic programs of patterned cell lineages in isolated vertebrate CNS ventricular zone cells

1998 • 243 citations

Dentate gyrus formation requires Emx2

1996 • 243 citations

The encephalomyocarditis virus internal ribosome entry site allows efficient coexpression of two genes from a recombinant provirus in cultured cells and in embryos.

1991 • 235 citations

A cell-intrinsic timer that operates during oligodendrocyte development

2000 • 234 citations

Systematic widespread clonal organization in cerebral cortex

1995 • 233 citations

Emx1 and Emx2 Show Different Patterns of Expression During Proliferation and Differentiation of the Developing Cerebral Cortex in the Mouse

1996 • 198 citations

Evidence for multiple precursor cell types in the embryonic rat cerebral cortex

1995 • 182 citations

Asymmetric division and polarity of neuroepithelial cells

1997 • 167 citations

Multiple restricted lineages in the embryonic rat cerebral cortex

1993 • 166 citations

The Lack ofEmx2Causes Impairment ofReelinSignaling and Defects of Neuronal Migration in the Developing Cerebral Cortex

2000 • 137 citations

EMX2 protein in the developing mouse brain and olfactory area

1998 • 130 citations

Expression of the Notch 3 intracellular domain in mouse central nervous system progenitor cells is lethal and leads to disturbed neural tube development

1996 • 120 citations

Evidence that retroviruses integrate into post-replication host DNA.

1993 • 110 citations

Emx2Is Required for Growth of the Hippocampus But Not for Hippocampal Field Specification

2000 • 109 citations

Local Homogeneity of Cell Cycle Length in Developing Mouse Cortex

1997 • 86 citations

Neocortical Development

1992 • 76 citations

Organotypic slice cultures for analysis of proliferation, cell death, and migration in the embryonic neocortex

1999 • 65 citations

The Specification of Neuronal Fate: A Common Precursor for Neurotransmitter Subtypes in the Rat Cerebral Cortex In Vitro

1995 • 63 citations

Stem cells in the embryonic cerebral cortex: Their role in histogenesis and patterning

1998 • 55 citations

Stem cells in the embryonic cerebral cortex: Their role in histogenesis and patterning

1998 • 48 citations

A Subset of Fibroblast Growth Factors (Fgfs) Promote Survival, but Fgf-8b Specifically Promotes Astroglial Differentiation of Rat Cortical Precursor Cells

1999 • 40 citations

PC3 overexpression affects the pattern of cell division of rat cortical precursors

2000 • 37 citations

Neuronal Clones in the Cerebral Cortex Show Morphological and Neurotransmitter Heterogeneity during Development

1996 • 27 citations

Neural development: Instructions for neural diversity

1997 • 24 citations

B-cell commitment: Pax5 is the deciding factor

1999 • 20 citations

Glial cell fate specification modulated by the bHLH gene Hes5 in mouse retina

2003 • 11 citations