The role(s) of lipophosphoglycan (LPG) in the establishment ofLeishmania majorinfections in mammalian hosts

Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids

1982 • 11,668 citations

Mouse model of X–linked chronic granulomatous disease, an inherited defect in phagocyte superoxide production

1995 • 920 citations

A limiting dilution assay for quantifying Leishmania major in tissues of infected mice

1985 • 508 citations

Stable transfection of the human parasite Leishmania major delineates a 30-kilobase region sufficient for extrachromosomal replication and expression.

1990 • 450 citations

Molecular Aspects of Parasite-Vector and Vector-Host Interactions in Leishmaniasis

2001 • 414 citations

A Lipophosphoglycan-Independent Method for Isolation of Infective Leishmania Metacyclic Promastigotes by Density Gradient Centrifugation

2001 • 369 citations

Leishmania species: models of intracellular parasitism

1999 • 347 citations

Role of the Leishmania surface protease gp63 in complement fixation, cell adhesion, and resistance to complement-mediated lysis.

1995 • 309 citations

Lipophosphoglycan is a virulence factor distinct from related glycoconjugates in the protozoan parasiteLeishmania major

2000 • 298 citations

Inhibition of Phagolysosomal Biogenesis by the Leishmania Lipophosphoglycan

1997 • 281 citations

Microbial glycolipids: possible virulence factors that scavenge oxygen radicals.

1989 • 255 citations

Targeted gene deletion in Leishmania major identifies leishmanolysin (GP63) as a virulence factor

2002 • 253 citations

Secretory Pathway of Trypanosomatid Parasites

2002 • 247 citations

Glycoconjugates in Leishmania infectivity

1999 • 218 citations

Oxygen metabolism and the microbicidal activity of macrophages.

1978 • 205 citations

Complement binding by two developmental stages of Leishmania major promastigotes varying in expression of a surface lipophosphoglycan.

1988 • 202 citations

The role of phosphoglycans inLeishmania–sand fly interactions

2000 • 198 citations

Cell Biology of Leishmania

1999 • 190 citations

Regulation of the expression of nitric oxide synthase and leishmanicidal activity by glycoconjugates of Leishmania lipophosphoglycan in murine macrophages.

1996 • 188 citations

Is lipophosphoglycan a virulence factor? A surprising diversity between Leishmania species

2001 • 171 citations

Intracellular trafficking and the parasitophorous vacuole of Leishmania mexicana-infected macrophages

1992 • 168 citations

Lipophosphoglycan (LPG) and the identification of virulence genes in the protozoan parasite Leishmania

1998 • 165 citations

Superoxide Dismutase-Deficient Mutants of Helicobacter pylori Are Hypersensitive to Oxidative Stress and Defective in Host Colonization

2001 • 153 citations

Mouse strains with typical mammalian levels of complement activity

1989 • 137 citations

Lipophosphoglycan is not required for infection of macrophages or mice by Leishmania mexicana

2000 • 134 citations

Inhibitory effects on protein kinase C activity by lipophosphoglycan fragments and glycosylphosphatidylinositol antigens of the protozoan parasite Leishmania

1989 • 131 citations

Leishmania donovani lipophosphoglycan selectively inhibits signal transduction in macrophages.

1991 • 130 citations

Glycoinositolphospholipids ofLeishmania major inhibit nitric oxide synthesis and reduce leishmanicidal activity in murine macrophages

1995 • 128 citations

Stable Transfection of the Human Parasite Leishmania major Delineates a 30-Kilobase Region Sufficient for Extrachromosomal Replication and Expression

1990 • 127 citations

Role of Salmonella typhimurium Mn-superoxide dismutase (SodA) in protection against early killing by J774 macrophages

1995 • 125 citations

Function and assembly of the Leishmania surface coat

2001 • 115 citations

Leishmania major:Promastigotes Induce Expression of a Subset of Chemokine Genes in Murine Macrophages

1997 • 108 citations

Regulation of macrophage IL-12 synthesis byLeishmania phosphoglycans

1999 • 92 citations

Leishmania, macrophages and complement: a tale of subversion and exploitation

1997 • 87 citations

Phosphoglycan Repeat-deficient Leishmania mexicana Parasites Remain Infectious to Macrophages and Mice

2001 • 86 citations

Leishmania-macrophage interactions: multiple receptors, multiple ligands and diverse cellular responses

1993 • 82 citations

Effect of glycolipids of Leishmania parasites on human monocyte activity. Inhibition by lipophosphoglycan.

1990 • 68 citations

Potent inhibition of viral fusion by the lipophosphoglycan of Leishmania donovani

1995 • 62 citations

Defective galactofuranose addition in lipophosphoglycan biosynthesis in a mutant of Leishmania donovani.

1993 • 57 citations

Exacerbation of experimental murine cutaneous leishmaniasis with CD4⁺Leishmania major‐specific T cell lines or clones which secrete interferon‐γ and mediate parasite‐specific delayed‐type hypersensitivity

1991 • 57 citations

Proteophosphoglycans from Leishmania promastigotes and amastigotes

1999 • 52 citations

The Role of Dendritic Cells at the Early Stages of Leishmania Infection

2002 • 43 citations

Development and characterization of a hemolytic assay for mouse C4

1980 • 41 citations

Inhibition of host cell signal transduction by Leishmania: observations relevant to the selective impairment of IL-12 responses

1999 • 37 citations

Lipophosphoglycan of the protozoan parasite Leishmania: stage- and species-specific importance for colonization of the sandfly vector, transmission and virulence to mammals

2001 • 35 citations

Variants with reduced virulence derived from Leishmania major after mutagen treatment

1987 • 34 citations

Histamine release from rat mast cells induced by protamine sulfate and polyethylene imine

1981 • 29 citations

Effects of xanthine: xanthine oxidase on membrane function: an in vitro model of endothelial damage.

1982 • 3 citations