Specific expression of a foreign β-globin gene in erythroid cells of transgenic mice

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids

1977 • 3,019 citations

Genetic transformation of mouse embryos by microinjection of purified DNA.

1980 • 1,428 citations

Mapping of RNA by a modification of the Berk-Sharp procedure: the 5′ termini of 15 S β-globin mRNA precursor and mature 10 S β-globin mRNA have identical map coordinates

1979 • 1,286 citations

Hereditary Anemias of the Mouse: A Review for Geneticists

1979 • 1,141 citations

Metallothionein-Human GH Fusion Genes Stimulate Growth of Mice

1983 • 699 citations

Somatic expression of herpes thymidine kinase in mice following injection of a fusion gene into eggs

1981 • 681 citations

Introduction of a rabbit β-globin gene into the mouse germ line

1981 • 458 citations

The Molecular Genetics of Human Hemoglobin

1984 • 420 citations

A single-base change at a splice site in a β0-thalassemic gene causes abnormal RNA splicing

1982 • 372 citations

Chromosomal position and activation of retroviral genomes inserted into the germ line of mice

1981 • 344 citations

Differences in human α- and β-globin gene expression in mouse erythroleukemia cells: The role of intragenic sequences

1984 • 312 citations

Introduction of a μ immunoglobulin gene into the mouse germ line: Specific expression in lymphoid cells and synthesis of functional antibody

1984 • 304 citations

The human beta-globin gene and a functional viral thymidine kinase gene in developing mice.

1981 • 285 citations

A foreign β-globin gene in transgenic mice: Integration at abnormal chromosomal positions and expression in inappropriate tissues

1983 • 245 citations

DNA sequences required for regulated expression of β-globin genes in murine erythroleukemia cells

1984 • 241 citations

Tissue-specific expression of the rat pancreatic elastase I gene in transgenic mice

1984 • 239 citations

Expression of a microinjected immunoglobulin gene in the spleen of transgenic mice

1983 • 202 citations

The regulated expression of β-globin genes introduced into mouse erythroleukemia cells

1983 • 186 citations

Mouse globin gene expression in erythroid and non-erythroid tissues

1976 • 136 citations

Expression of the chicken transferrin gene in transgenic mice

1983 • 126 citations

High expression of cloned immunoglobulin k gene in transgenic mice is restricted to B lymphocytes

1984 • 114 citations

Regulated expression of the human β-globin gene family in murine erythroleukaemia cells

1983 • 112 citations

Specific representation of cloned repetitive DNA sequences in sea urchin RNAs

1978 • 101 citations

Cloning and amplification of α and β mouse globin gene sequences synthesised in vitro

1977 • 99 citations

Human β-Globin Gene Sequences Injected into Mouse Eggs, Retained in Adults, and Transmitted to Progeny

1982 • 90 citations

Increase in the accumulation of globin mRNA in immature erythroblasts in response to erythropoietin in vivo or in vitro

1975 • 31 citations