CD45‐mediated regulation of LFA1 function in human natural killer cells. Anti‐CD45 monoclonal antibodies inhibit the calcium mobilization induced via LFA1 molecules

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Adhesion receptors of the immune system

1990 • 6,585 citations

Biology of Natural Killer Cells

1989 • 2,970 citations

Purified intercellular adhesion molecule-1 (ICAM-1) is a ligand for lymphocyte function-associated antigen 1 (LFA-1)

1987 • 1,712 citations

The Lymphocyte Function Associated LFA-1, CD2, and LFA-3 Molecules: Cell Adhesion Receptors of the Immune System

1987 • 1,104 citations

A human leukocyte differentiation antigen family with distinct alpha-subunits and a common beta-subunit: the lymphocyte function-associated antigen (LFA-1), the C3bi complement receptor (OKM1/Mac-1), and the p150,95 molecule.

1983 • 888 citations

The Leukocyte Common Antigen Family

1989 • 741 citations

Leukocyte Typing II

1986 • 688 citations

[41] Use of vanadate as protein-phosphotyrosine phosphatase inhibitor

1991 • 583 citations

Characterization of ICAM-2 and evidence for a third counter-receptor for LFA-1.

1991 • 510 citations

Evidence that the leukocyte-common antigen is required for antigen-induced T lymphocyte proliferation

1989 • 509 citations

Intercellular adhesion molecule 3, a third adhesion counter-receptor for lymphocyte function-associated molecule 1 on resting lymphocytes.

1992 • 437 citations

The leukocyte common antigen (CD45): a putative receptor-linked protein tyrosine phosphatase.

1988 • 435 citations

Demonstration that the leukocyte common antigen (CD45) is a protein tyrosine phosphatase

1988 • 425 citations

Identification of four subsets of human CD3-CD16+ natural killer (NK) cells by the expression of clonally distributed functional surface molecules: correlation between subset assignment of NK clones and ability to mediate specific alloantigen recognition.

1990 • 388 citations

Primary structure of the leukocyte function-associated molecule-1 alpha subunit: an integrin with an embedded domain defining a protein superfamily.

1989 • 285 citations

The cytoplasmic domain of the integrin lymphocyte function-associated antigen 1 beta subunit: sites required for binding to intercellular adhesion molecule 1 and the phorbol ester-stimulated phosphorylation site.

1991 • 241 citations

CD45 regulates signal transduction and lymphocyte activation by specific association with receptor molecules on T or B cells.

1988 • 223 citations

On the mode of action of LFA-1

1990 • 208 citations

Fc gamma R(CD16) interaction with ligand induces Ca2+ mobilization and phosphoinositide turnover in human natural killer cells. Role of Ca2+ in Fc gamma R(CD16)-induced transcription and expression of lymphokine genes.

1989 • 208 citations

Heterogeneous distribution and transmembrane signaling properties of lymphocyte function-associated antigen (LFA-1) in human lymphocyte subsets.

1989 • 158 citations

Constitutive and induced phosphorylation of the alpha- and beta-chains of the CD11/CD18 leukocyte integrin family. Relationship to adhesion-dependent functions.

1990 • 158 citations

Antigen-receptor complex stimulation triggers protein kinase C-dependent CD11a/CD18-cytoskeleton association in T lymphocytes.

1992 • 131 citations

Kinases and phosphatases in T-cell activation

1989 • 118 citations

T-Cell Effector Functions: Mechanisms for Delivery of Cytotoxicity and Help

1991 • 103 citations

A monoclonal antibody to the human leukocyte adhesion molecule intercellular adhesion molecule-2. Cellular distribution and molecular characterization of the antigen.

1991 • 92 citations

Isoform‐specific associations of CD45 with accessory molecules in human T lymphocytes

1992 • 84 citations

Blockade of NK cell lysis is a property of monoclonal antibodies that bind to distinct regions of T-200.

1983 • 66 citations

A second signal for T cell mitogenesis provided by monoclonal antibodies CD45 (T200)

1987 • 64 citations

Interaction between the CD45 antigen and phytohemagglutinin. Inhibitory effect on the lectininduced T cell proliferation by anti‐CD45 monoclonal antibody

1987 • 57 citations

Surface antigens on mouse natural killer cells: use of monoclonal antibodies to inhibit or to enrich cytotoxic activity.

1981 • 52 citations

CD3⁺ WT31⁻ peripheral T lymphocytes lack T44 (CD28), a surface molecule involved in activation of T cells bearing the α/β heterodimer

1987 • 50 citations

A FUNCTION FOR HUMAN T200 IN NATURAL KILLER CYTOLYSIS

1983 • 42 citations

Human cytolytic cell clones lacking surface expression of T cell receptor alpha/beta or gamma/delta. Evidence that surface structures other than CD3 or CD2 molecules are required for signal transduction.

1988 • 39 citations

In vitro expansion of CD3/TCR- human thymocyte populations that selectively lack CD3 delta gene expression: a phenotypic and functional analysis.

1990 • 38 citations

A novel antigenic cell surface protein associated with T200 is involved in the post-activation stage of human NK cell-mediated lysis.

1984 • 32 citations

BLOCKING OF CYTOTOXIC T CELL FUNCTION BY MONOCLONAL ANTIBODIES AGAINST THE CD45 ANTIGEN (T200/LEUKOCYTE-COMMON ANTIGEN

1987 • 21 citations

Evidence that the CD45 phosphatase regulates the activity of the phospholipase C in mouse T lymphocytes

1991 • 18 citations

CD45 molecule cross-linking inhibits natural killer cell-mediated lysis independently of lytic triggering.

1990 • 9 citations